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Marta Porniece

@martaapp.bsky.social

🇱🇻🇩🇪🇺🇸 #WalterBenjamin Postdoc @bostonchildrens.bsky.social‬, @bidmcreseach.bsky.social‬, ‪@harvardmed.bsky.social, alumni of ‪@mpi-metabolism.bsky.social‬, Non-neuronal cells, hormones, obesity. Into 🏃🏻‍♀️🍦🍓

14 Posts51 Follower 97 Folgt

Marta Porniece @martaapp.bsky.social · 10mo ago

1️⃣ 🥳 Thrilled to share that my postdoc work has finally hit the press! www.nature.com/articles/s41... When we started, we didn’t really know what PVH-MC4R neurons do in obesity. Are they still signaling or “dead”? (e.g., does the chronically high leptin alter α-MSH–MC4R signaling?) 🧵👇

Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons - Scientific Reports

Scientific Reports - Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons

nature.com

MPI-Metabolism @mpi-metabolism.bsky.social · last yr.

Exciting news from @sophiesteculorum.bsky.social Lab!🤓 👃🧠 Smelling food primes your brain for satiety. Find out more in 🧵 or under 🔗 www.nature.com/articles/s42... Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism

The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

nature.com

Praneel Sunkavalli @praneelsunkavalli.bsky.social · last yr.

I am excited to share our preprint on how hypothalamic dopamine neurons govern slow changes in motivation over days! Below are our findings: www.biorxiv.org/content/10.1...

Slow-Timescale Regulation of Dopamine Release and Mating Drive over Days

The rise and fall of motivational states may take place over timescales as long as many days. We used mouse mating behavior to model how the brain orchestrates slow-timescale changes in motivation. Ma...

biorxiv.org

Marta Porniece @martaapp.bsky.social · last yr.

🚨 Paper alert! 📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience

Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons

Melanocortin-4 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus (PVHMC4R) integrate hunger-promoting and hunger-suppressing signals to regulate satiety. Food consumption-...

biorxiv.org