Launch of our brand-new website for ๐๐๐๐ฉ๐๐ ! ๐ ๐ Explore: deepof.ai
DeepOF ๏ฟฝ Supervised and Unsupervised Behavioral Analysis
DeepOF: An open-source Python library for mouse behavioral analysis.
deepof.ai
Mathias V. Schmidt
@mathiasvschmidt.bsky.social
Unraveling the molecular basis of stress resilience | Group leader at MPI of Psychiatry | Secretary General Elect of FENS | Editor-in-Chief Neurobiology of Stress
Launch of our brand-new website for ๐๐๐๐ฉ๐๐ ! ๐ ๐ Explore: deepof.ai
DeepOF ๏ฟฝ Supervised and Unsupervised Behavioral Analysis
DeepOF: An open-source Python library for mouse behavioral analysis.
deepof.ai
Stress and resilience researchers - check out this fantastic satellite event just before the start of the European College of Neuropsychopharmacology (ECNP) Meeting in Munich. We have a fantastic lineup of speakers. Registration (free) is now open: lnkd.in/gMsV4Ygc
Stress and resilience researchers - check out this fantastic satellite event just before the start of the European College of Neuropsychopharmacology (ECNP) Meeting in Munich. We have a fantastic lineup of speakers. Registration (free) is now open: lnkd.in/gMsV4Ygc
Am 5. Mai gibt uns Biologe und Forschungsgruppenleiter @mathiasvschmidt.bsky.social einen Einblick in seine Forschung zum Thema Stress. Die Veranstaltung ist fรผr alle offen, eine Anmeldung ist nicht nรถtig! Mehr Infos findet ihr hier: www.psych.mpg.de/mindmatters #biologie #stress #vortrag
We are really thrilled to host this joint open special issue with among the two journals @mathiasvschmidt.bsky.social We are very interested to receive your best research at the intersection between stress, health and aging. Details here lnkd.in/dGfV24ex and in the linkedin post z.umn.edu/b971
๐๐๐ฐ ๐๐จ๐ข๐ง๐ญ ๐๐๐ฅ๐ฅ ๐๐จ๐ซ ๐๐๐ฉ๐๐ซ๐ฌ: ๐๐ญ๐ซ๐๐ฌ๐ฌ ๐๐ง๐ ๐๐๐๐๐ฅ๐๐ซ๐๐ญ๐๐ ๐๐ ๐ข๐ง๐ I am thrilled to announce a unique editorial collaboration between ๐๐๐ฎ๐ซ๐จ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐จ๐โฆ | PD Dr. Mathias V. Schmidt
๐๐๐ฐ ๐๐จ๐ข๐ง๐ญ ๐๐๐ฅ๐ฅ ๐๐จ๐ซ ๐๐๐ฉ๐๐ซ๐ฌ: ๐๐ญ๐ซ๐๐ฌ๐ฌ ๐๐ง๐ ๐๐๐๐๐ฅ๐๐ซ๐๐ญ๐๐ ๐๐ ๐ข๐ง๐ I am thrilled to announce a unique editorial collaboration between ๐๐๐ฎ๐ซ๐จ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐จ๐ ๐๐ญ๐ซ๐๐ฌ๐ฌ and ๐๐๐ฎ๐ซ๐จ๐ฌ๐๐ข๐๐ง๐๐ ๐๐ง๐ ๐๐ข๐จ๐๐๐ก๐๐ฏ๐ข๐จ๐ซ๐๐ฅ ๐๐๐ฏ๐ข๐๐ฐ๐ฌ. Together ...
linkedin.com
๐๐๐ฐ ๐๐จ๐ข๐ง๐ญ ๐๐๐ฅ๐ฅ ๐๐จ๐ซ ๐๐๐ฉ๐๐ซ๐ฌ I am thrilled to announce an editorial collaboration between ๐๐๐ฎ๐ซ๐จ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐จ๐ ๐๐ญ๐ซ๐๐ฌ๐ฌ and ๐๐๐ฎ๐ซ๐จ๐ฌ๐๐ข๐๐ง๐๐ ๐๐ง๐ ๐๐ข๐จ๐๐๐ก๐๐ฏ๐ข๐จ๐ซ๐๐ฅ ๐๐๐ฏ๐ข๐๐ฐ๐ฌ. With @bartolomuccilab.bsky.social, I am co-editing a virtual special issue focused on: ๐๐ต๐ณ๐ฆ๐ด๐ด-๐ช๐ฏ๐ฅ๐ถ๐ค๐ฆ๐ฅ ๐ช๐ฎ๐ฑ๐ข๐ช๐ณ๐ฆ๐ฅ ๐ฉ๐ฆ๐ข๐ญ๐ต๐ฉ ๐ข๐ฏ๐ฅ ๐ข๐ค๐ค๐ฆ๐ญ๐ฆ๐ณ๐ข๐ต๐ฆ๐ฅ ๐ข๐จ๐ช๐ฏ๐จ
๐๐๐ฐ ๐๐จ๐ข๐ง๐ญ ๐๐๐ฅ๐ฅ ๐๐จ๐ซ ๐๐๐ฉ๐๐ซ๐ฌ I am thrilled to announce an editorial collaboration between ๐๐๐ฎ๐ซ๐จ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐จ๐ ๐๐ญ๐ซ๐๐ฌ๐ฌ and ๐๐๐ฎ๐ซ๐จ๐ฌ๐๐ข๐๐ง๐๐ ๐๐ง๐ ๐๐ข๐จ๐๐๐ก๐๐ฏ๐ข๐จ๐ซ๐๐ฅ ๐๐๐ฏ๐ข๐๐ฐ๐ฌ. With @bartolomuccilab.bsky.social, I am co-editing a virtual special issue focused on: ๐๐ต๐ณ๐ฆ๐ด๐ด-๐ช๐ฏ๐ฅ๐ถ๐ค๐ฆ๐ฅ ๐ช๐ฎ๐ฑ๐ข๐ช๐ณ๐ฆ๐ฅ ๐ฉ๐ฆ๐ข๐ญ๐ต๐ฉ ๐ข๐ฏ๐ฅ ๐ข๐ค๐ค๐ฆ๐ญ๐ฆ๐ณ๐ข๐ต๐ฆ๐ฅ ๐ข๐จ๐ช๐ฏ๐จ
I am delighted to share our editorial for Neurobiology of Stress, co-authored with my fellow Editor-in-Chief, Lawrence Reagan doi.org/10.1016/j.yn...
Redirecting
doi.org
Iโm thrilled to share our latest preprint from the lab, now available on BioRxiv! We investigated how early life adversity (ELA) shapes the adult brain, and the results are a stark reminder that sex isn't just a variable but leads to fundamentally different stress-induced mechanistic consequences
To truly understand the neurobiological basis of complex behaviors - the real ๐ฆ๐๐๐ง๐ข๐ง๐ ๐จ๐ ๐ฅ๐ข๐๐, ๐ญ๐ก๐ ๐ฎ๐ง๐ข๐ฏ๐๐ซ๐ฌ๐, ๐๐ง๐ ๐๐ฏ๐๐ซ๐ฒ๐ญ๐ก๐ข๐ง๐ - we must overcome the limitations of traditional, short-term behavioral tests.
๐จOpen position at #FENS! ๐ญDo you want to help strengthen the voice of #neuroscience? Apply for the Advocacy and Engagement Internship at FENS! ๐๏ธ The deadline for applications is 31 October! ๐ https://loom.ly/2Qy18y8
Very happy to share our new paper in Biological Psychiatry, showing that Urolithin A reverses high anxiety by repairing mitochondrial function in the nucleus accumbens. Big kudos to first co-authors David Mallet & Doฤukan รlgen, our amazing team, and collaborators! ๐ Paper: doi.org/10.1016/j.bi...
Redirecting
doi.org
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in: www.biorxiv.org/content/10.1...
Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling
Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear. Here, we probed the di...
biorxiv.org
Ready for some really hot ๐ฅ๐ฅต data on stress and trauma effects across the life span, join us at the 17:30 symposium @ebbsociety.bsky.social with @biancasilvalab.bsky.social.
The heat wonโt stop the energy โ science (and fans!) in full swing! ๐๐ชญ๐ช #EBBS2025
๐จ NEW PAPER ๐จ Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Expanding our understanding of (mal)adapted stress physiology in psychiatric disorders: achieving single-cell characterisation of steroids and neuropeptides
Steroid hormones and neurosteroids (collectively neuroactive steroids), alongside neuropeptides, are key modulators of the central nervous system. Theโฆ
sciencedirect.com
๐It's happening - The Neurobiology of Grief International Network (NOGIN) comes to Europe! We are happy to host NOGIN from Sept 17-19 in Regensburg/DE. Registration is already open, seats are strictly limited to 100 participants. More information here: www.neurobiologyofgrief.org/events
Events โ Neurobiology of Grief International Network
neurobiologyofgrief.org
Excellent review by @talliezee.bsky.social and Matthew T. Birnie on the neurobiological mechanisms underlying the consequences of early life adversity. Highly recommended! www.cell.com/neuron/fullt...
The evolving neurobiology of early-life stress
This review explores the effects of early-life stress on brain development and cognitive function, highlighting gaps in understanding perceived stress, vulnerable developmental stages, underlying mole...
cell.com
Childhood adversity as a risk factor for autoimmune disease: A systematic review and meta-analysis with implications for psychiatry www.sciencedirect.com/science/arti...
Childhood adversity as a risk factor for autoimmune disease: A systematic review and meta-analysis with implications for psychiatry
Autoimmune diseases are a heterogeneous category of disorders caused by an interaction between genetic and environmental factors which lead to a dysreโฆ
sciencedirect.com
Read about our recent discoveries on mechanisms that can drive resilience in females. www.psych.mpg.de/2949097/news...
Early Life Stress Can Build Resilience in Females
Stress in early life can improve emotional regulation and cognitive function in female mice. This is a significant departure from the traditional view that such stress is solely detrimental. The study...
psych.mpg.de
The Peter Seeburg Integrative Neuroscience Prize honors groundbreaking work that bridges molecular & systems neuroscience to advance our understanding of cognition, emotion, memory, & decision-making. ๐ฌ Celebrate bold science. Nominate now. #Neuroscience #BrainResearch www.sfn.org/careers/awar...
Peter Seeburg Integrative Neuroscience Prize
sfn.org
Intergenerational Effects of Stress - A Focus on Learning and Memory doi.org/10.1007/7854...
Intergenerational Effects of Stress โ A Focus on Learning and Memory
Stress is a ubiquitous facet of life. Ranging in form (e.g., psychosocial, physical, nutritional, economic) and longevity (e.g., acute, chronic), stressors affect the biology of those directly in thei...
doi.org
We're using a lab TikTok account to try and get the message out about why science is important. The latest post from @neurani.bsky.social and @g-lia-lcells.bsky.social with footage from Hunter Sowards lab visit www.tiktok.com/t/ZP82fpRCA/
lab but aesthetic ๐คฉ comment how a typical day looks for you #sza #dayinlife #interviews #science #lablife #labtech #behindthescene
TikTok video by trainor lab
tiktok.com
New paper: We show that especially female mice benefit from moderate early life adversity under stressful situations in adulthood. This pro-resilient effect requires the psychiatric risk factor FKBP51, which turns out to be also required for adaptive stress responses. www.nature.com/articles/s41...
FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice - Nature Communications
Early life stress can induce lasting changes in brain function and behavior. Here, authors show that glutamatergic FKBP51 specifically in females mediates adaptive stress effects on anxiety and cognit...
nature.com
Maternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis www.nature.com/articles/s41...
Maternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis - Nature Communications
Early life experience modulates stress resilience in later life. Here the authors show that maternal care triggers microglia-derived IGF-1 levels, which suppresses the neuronal C/EBPฮฒ-DRP1 axis, promo...
nature.com
๐จ๐ง New paper alert: Stress alters neuronal balance in the developing brain ๐ง ๐จ Our latest study in @science.orgAdvances explores how glucocorticoid exposureโa key environmental risk factorโshapes early human brain development using #organoids. @mpi-psychiatry.bsky.social @drcricru.bsky.social ๐งต๐
Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids
Chronic exposure to glucocorticoids during brain development leads to priming of the inhibitory neuron lineages in organoids.
science.org