Matt Yousefzadeh
@mattyousefzadeh.bsky.social
An aging aging biologist.
grants.nih.gov/grants/guide...
NOT-OD-26-086: Request for Information: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator to Support More Researchers and Maximize Scientific Productivity a...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator ...
grants.nih.gov
What do 🍓🍓🍓 have to do with aging? Check out the Immunoschool program and see if you can figure out the 🍓related topic, inspired by research from @mattyousefzadeh.bsky.social and others on immune-driven tissue decline and new ways to slow, halt or even reverse it. PROGRAM: immunoschool.org
I know some deals actually get done there but convince me that JPM is not the Coachella of the biotech world?
There are two types of people in this world: 1. Good people. 2. Those who leave a spent K cup in the Keurig coffee maker and don't refill the water tank. I just realize this morning, I'm #2. I live alone, no one else to blame.
For those of you attending #GSA2025 in Boston, consider this panel of #NIH awardees, Drs. Alden Gross, @mariaglymour.bsky.social , @sfackley.bsky.social , and @bryandjames.bsky.social. Please remember to tag #geronsky and @geronsociety.bsky.social in your posts.
📢📢Apply now for GRS/GRC on DNA Damage Mutation & Cancer in sunny Ventura CA.
Metztli Cisneros-Aguirre@cisnerosmetztli.bsky.social · 11mo ago🧬Register for the GRS on DNA Damage, Mutation & Cancer🧬 Feb 28–Mar 1 2026, Ventura CA Accepting abstracts for oral presentations! 📍 Apply here 👉 grc.org/dna-damage-mutation-and-cancer-grs-conference/2026 (www.grc.org/dna-damage-m...) #DNADamage #GRC#GRS #CallForAbstracts
First, pos-neg gating. Ideal controls are your actual antibodies on the actual cells. However different antibodies bind different cells (see: CD4 vs XCR1 below), meaning they have different backgrounds to control. AutoSpectral matches the FSC-SSC of each pos to a suitable neg: with results!
Indoor Rewilding of Laboratory Mice Recalibrates Pulmonary Mucosal Immunity and Mechanics @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Looks like Hevolution is not funding anything (GRO, postdoc, etc.) from the 2024 cycle?
Pro tip: make sure your myNCBI profile is linked to your eRA account and that you link awards to papers directly in there.
www.biorxiv.org/content/10.1...
Evidence for an energetic trade-off model linking inflammaging and immunosenescence in the US Health and Retirement Study and UK Biobank
Later life is characterized by the development of chronic inflammation, termed inflammaging, alongside changes in immune cell profiles, or immunosenescence. While these features contribute to health r...
biorxiv.org
www.biorxiv.org/content/10.1...
THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
A growing number of therapies are being developed to target the cell cycle machinery for the treatment of cancer and other human diseases. Consequently, a greater understanding of the factors regulati...
biorxiv.org
Current mood while writing up a specific aims page.
Very cool. currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
Introducing the Dish Soap Protocol: A Unified Approach for Multi‐Modal Intracellular Staining
Recent advances in dyes and cytometers have seen an exponential increase in the ability to perform multidimensional flow cytometry. As we increase our capacity to extract information from cells, the ....
currentprotocols.onlinelibrary.wiley.com
🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/
We are so glad to share that the Nathan Shock Centers Coordinating Center (NSC3) will continue its mission after receiving a five-year grant renewal! The American Federation for Aging Research (AFAR) will lead NSC3 activities with the $5.7 million NIH award. Read more here: bit.ly/45yQz2B
Program staff reductions at the NIH ICs drugmonkey.wordpress.com/2025/08/22/p...
Program staff reductions at the NIH ICs
Propublica has published a report on the loss of staff positions at various government agencies since January of 2025. This includes a list of percent losses at each NIH IC due to firings, layoffs,…
drugmonkey.wordpress.com
The application for the The Department of Biochemistry & Physiology Assistant Professor/Faculty Position is open now! Apply now if you're interested in investigating inflammation, cellular senescence, immunology, lipid metabolism, and/or neurodegeneration! 🧠 🔗 jobs.sciencecareers.org/job/674553
www.science.org/doi/10.1126/...
Sex differences in tissue-specific immunity and immunology
Biological sex exerts a substantial influence on the immune system and immune-related diseases. Males are more susceptible to the acute effects of viral disease and certain cancers, whereas females ex...
science.org
Much thanks to Sandra Delgado-Pulido and Maria Mittelbrunn for letting me be a part of this perspective describing how an aged adaptive immune system can go off the rails to disrupt tissue homeostasis and drive aging. www.nature.com/articles/s43...
Aging reshapes the adaptive immune system from healer to saboteur - Nature Aging
Delgado-Pulido, Yousefzadeh and Mittelbrunn explore the molecular mechanisms by which adaptive immunity regulates the processes of aging, discussing age-related declines in protective functions and ag...
nature.com
Great collection of articles on senescence & aging derived from the recent CSHL 2025 Symposium
Genes & Development@genesdev.bsky.social · last yr.NEW ISSUE ALERT!!! Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer. Online now: ➡️ genesdev.cshlp.org/content/39/1...
Travel awards are available for the NIA Geroscience Education and Training (GET) Network Workshop, where attendees can learn how to educate aspiring translational geroscientists, and introduce graduate students, medical students, or geriatrics fellows to geroscience. Learn more here: bit.ly/4ozUALB
Anyone ever run into this situation? Ran our RNA samples on the Qubit for their RNA IQ assay and it came out looking great (9/10) but was absolute dogdish on the bioanalzyer (RINs in the 2's).
TERT (telomerase) can regulate physiological levels of inflammatory signals independently of its catalytic functions www.nature.com/articles/s41... www.nature.com/articles/s41...
