"Fungal resistance is a silent and underestimated threat. The same substances helping to protect crops are also reducing the effectiveness of essential medicines. If we fail to act, we risk losing critical treatments and putting lives at risk” @mbottery.bsky.social www.fungalamr.org/post/three-u...

MEEHubs2026 registration and abstract submission is now online! 🚨🦠✨ Join us Aug 3 - 5, 2026 at one of the 7 hubs or online. We are incredibly excited about our lineup of speakers, and hope that you submit an abstract to contribute too! More information and registration links at: meehubs.org

PhD Opportunity: Are you interested in evolutionary biology and the global challenge of antifungal resistance? We are seeking a motivated candidate for a President’s Doctoral Scholar Award 📅Deadline: March 16 2026 📍Location: @manchester.ac.uk @fbmh-uom.bsky.social www.findaphd.com/phds/project...

(PDS) Targeting Septal Plugging to Disrupt the Evolution of Antifungal Resistance in Hyphal Networks at The University of Manchester on FindAPhD.com

PhD Project - (PDS) Targeting Septal Plugging to Disrupt the Evolution of Antifungal Resistance in Hyphal Networks at The University of Manchester, listed on FindAPhD.com

findaphd.com

Presenting my perspective on the role of academic science on the issues of antifungal dual use at the Brazilian Network Meeting on Aspergillus fumigatus Antimicrobial Resistance. @f1amr-network.bsky.social @fbmh-uom.bsky.social

Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech. Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!

Currently hosting event on antifungals in medicine and agriculture, focusing on #AntiMicrobialResistance #AMR. With 6.5 million invasive infections globally each year, and 3.8 million deaths attributable to them. Area of fast-rising concern!

Very proud of Ed's first conference talk at #BSMM2025 did great despite the technical hiccups!!

Interested in working on Mucorales adaptation? Thanks to new funding from @wellcometrust.bsky.social, we will have two postdoc and a technician positions advertised very soon! if interested, please get in touch for more information.

Thrilled to announce I've been awarded a @wellcometrust.bsky.social Career Development Award at @fbmh-uom.bsky.social , University of Manchester! My research will investigate the remarkable adaptability of Aspergillus fumigatus, a deadly fungal pathogen, to help combat drug resistance.

The MHRA today released new guidance for #Phage therapy in the UK. This will provide direction for scientists and researchers working to make this treatment a reality for patients. 🔬 🧪 🔗 www.gov.uk/government/n...

New preprint with nice detective work by PhD student Khadija Hanga: gain of pOXA MDR plasmid is facilitated by chromosomal mutations affecting OmpF which act synergistically with the plasmid’s carbapenamase to give high level resistance. Led by @mbottery.bsky.social www.biorxiv.org/content/10.1...

Chromosomal resistance mutations facilitate acquisition of multidrug-resistance plasmids in Escherichia coli

Bacteria can gain multiple resistance mechanisms in a single step by the acquisition of multidrug-resistance (MDR) plasmids, but it is unclear how antibiotic selection during the acquisition of MDR pl...

biorxiv.org

@wellcometrust.bsky.social Thanks for organizing the ERC meeting. I found the research culture activity really helpful, so many great thought-provoking ideas

Beautiful day to get out of the office and do some fieldwork! Soil samples + 🍄 #failsafe #mycology @normanvanrhijn.bsky.social

New in Nature Comms, we show that azole-resistant Aspergillus fumigatus are more likely to evolve resistance to new antifungals due to variants in their DNA mismatch repair system rdcu.be/d3Iyc @natureportfolio.bsky.social #microsky #fungi #amr

Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance

Nature Communications - Here, Bottery et al show that resistance to next generation antifungals is more likely to occur within azole resistant Aspergillus fumigatus due to the close linkage between...

rdcu.be

In case you missed it: @matthewjshepherd.bsky.social surveyed the clinical literature to reveal how #AMR evolves within patients, why eco/evo mechanisms vary among infections, & what we can do better to improve treatments www.nature.com/articles/s41... #MicroSky

Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance - Nature Reviews Microbiology

In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...

nature.com

It was great fun to be part of this project! Super cool to see Rock-Paper-Scissors dynamics in real microbial populations

Jamie Hall@jpjhall.bsky.social · 2y ago

🆕New in @plosbiology.bsky.social: we show compensatory mutations make plasmids play Rock-Paper-Scissors and turn conjugation into a weapon🛡️💫✂️🦠 w/Rosanna Wright, Jamie Wood, @mbottery.bsky.social, @kmudz.bsky.social, @scottishwormboy.bsky.social, Ellie Harrison & @brockhurstlab.bsky.social #MicroSky

PhD studentship alert! Fully funded, co-supervised with @rokkrasovec.bsky.social and Prof Mike Bromley, University of Manchester Exploring routes of horizontal gene transfer in pathogenic fungi Exciting project, will be a bunch of fun! Come & join us 🔬 www.findaphd.com/phds/project...

Soil microbiomes show consistent and predictable responses to extreme events We’re out in Nature !! doi.org/ntzk Very exciting for my first bluesky post! – it’s been a long haul by an excellent team from across Europe, led by @frantecol.bsky.social

Soil microbiomes show consistent and predictable responses to extreme events - Nature

Soils from 30 grasslands across Europe were subjected to 4 contrasting extreme climatic events under drought, flood, freezing and heat conditions, with the results suggesting that soil microbiomes fro...

doi.org

Fungal Genetics Stock Centre, there's something fishy going on here...

It was a pleasure to have the opportunity to present our work!

Prof Paula Salgado@pssalgado.bsky.social · 2y ago

We now have Michael Bottery from Manchester Univ on his work on #AMR in Aspergillus fumigatus #WAAW #microSky

Excited to be giving a talk this afternoon on the risk of AMR evolution in fungal pathogens @newcastleuni.bsky.social #WAAW #AMR