Michael Ferraro
@mcferraro.bsky.social
Doctoral candidate, NeuRA & UNSW Medicine
Retracted studies keep getting cited — even after retraction. We evaluated whether we could improve journal policies to prevent citation of retracted research across top anaesthetics and pain journals. Full text: associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/epub/10....
An audit and feedback intervention to reduce inappropriate citation of retracted anaesthetic and pain medicine publications
associationofanaesthetists-publications.onlinelibrary.wiley.com
Low back pain is defined as pain located below the costal margin and above the inferior gluteal folds, with or without leg pain and is the leading cause of years lived with disability worldwide, affecting people of all ages. Learn more in this Review: ja.ma/3SbmHVN
Out today in @annalsofim.bsky.social doi.org/10.7326/ANNA... Our systematic review of 11 RCTs found bisphosphonates may reduce short-term pain but increase risk for AEs. Results limited by substantial, unexplained heterogeneity, introduced by inclusion of terminated trial data.
Efficacy and Safety of Bisphosphonates for Complex Regional Pain Syndrome: A Systematic Review and Meta-analysis: Annals of Internal Medicine: Vol 0, No 0
Background: Clinical guidelines recommend bisphosphonates for complex regional pain syndrome (CRPS) despite limited evidence of efficacy. Purpose: To determine the efficacy and safety of bisphosphonat...
doi.org
www.medrxiv.org/content/10.1... INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
medrxiv.org
To do no harm, we must first “know harms” Our new perspective piece on the challenge of measuring and reporting adverse events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social
To do no harm, we must first “know harms”. The challenge of ... : PAIN
An abstract is unavailable.
dx.doi.org
Is medical practice ahead of the evidence?
Michael Ferraro@mcferraro.bsky.social · 12mo agoOut today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...
@efic.bsky.social @britishpainsoc.bsky.social @auspainsoc.bsky.social
Michael Ferraro@mcferraro.bsky.social · 12mo agoOut today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...
Out today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...
Ketamine and other NMDA receptor antagonists for chronic pain - Ferraro, MC - 2025 | Cochrane Library
Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.
doi.org
Despite a large body of new evidence, our best treatments for neuropathic pain continue to provide only modest benefits, write Michael Ferraro and Dr Nadia Soliman buff.ly/F5irUsl
One-Page Patient Fact Sheets for Low Back Pain in Primary Care url:https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2836549?utm_source=bluesky&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=072425
Despite a large body of new evidence, our best treatments for neuropathic pain continue to provide only modest benefits, write Michael Ferraro and Dr Nadia Soliman buff.ly/F5irUsl
🥁 This week, we submitted to BMC medicine our stage 2 registered report "Efficacy and safety of esketamine for ‘treatment-resistant depression’: registered report for a systematic review with an individual patient data meta-analysis of randomized, double-blind, placebo-controlled trials". 🧵
Efficacy and safety of esketamine for treatment resistant depression: registered report for a Systematic Review with an Individual Patient Data Meta-analysis of Randomized, Double-Blind, Placebo-Contr...
Background In 2019, the FDA and EMA approved intranasal esketamine for treatment resistant depression (TRD). The current study re–evaluated its efficacy and safety. Methods This registered report pres...
medrxiv.org
RCT: Among patients with low back pain, a nondirective information sheet listing treatment options improved patient-reported preparedness for decision-making more than a directive advice sheet. https://ja.ma/4nUr96z
One-Page Patient Fact Sheets for Low Back Pain in Primary Care Fact sheets do better than regular advice to support shared decision making! jamanetwork.com/journals/jam...
One-Page Patient Fact Sheets for Low Back Pain in Primary Care
This randomized clinical trial compares the effects of 1-page fact sheets that adopt either an information-listing approach or a direct advice approach on management of low back pain to prepare patien...
jamanetwork.com
Delighted that the editors of 15 Pain and Anaesthesiology have chosen to endorse and amplify the ENTRUST-PE framework. More info here: www.linkedin.com/pulse/entrus... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social @ukrio.bsky.social @coarassessment.bsky.social
ENTRUST-PE: endorsement by senior editors of 15 Pain and Anaesthesiology Journals
We are beyond delighted that the ENTRUST-PE framework has been endorsed by the Editors in Chief of 15 International Pain and Anaesthesiology journals. Those editors are copublishing, across the journa...
linkedin.com
#PAIN joins with other editors of pain-related journals to affirm our editorial commitment to trust and integrity in science. Read our joint statement at bit.ly/4lj3b3b
Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: doi.org/10.1016/j.jp...
Redirecting
doi.org
Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research journals.lww.com/pain/fulltex...
Editorial commitment to trust and integrity in science:... : PAIN
An abstract is unavailable.
journals.lww.com
Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project
The aim of the INSPECT-SR project is to develop a tool to identify problematic RCTs in systematic reviews. In Stage 1 of the project, a list of potential trustworthiness checks was created. The checks...
jclinepi.com
International #ResearchIntegrity conference taking place in beautiful Sydney Australia on 16-18 November 2025 🐨 🌏 Great speakers including @elisabethbik.bsky.social @jdwilko.bsky.social @jasonchin.bsky.social For more info contact @simongandevia.bsky.social 🧪
Simon Gandevia@simongandevia.bsky.social · last yr.International Research Integrity Conference. I am arranging this in Sydney in November 16-18th 2025. researchintegrityconf.com Note the excellent speaker list. Contact me!
International Research Integrity Conference. I am arranging this in Sydney in November 16-18th 2025. researchintegrityconf.com Note the excellent speaker list. Contact me!
International Research Integrity Conference | 17-18 November 2025, Sydney, Australia
researchintegrityconf.com
www.bmj.com/content/389/... "Evidence from 68 systematic reviews with conclusions distorted by retracted trials was used in 157 guideline documents."
Investigating the impact of trial retractions on the healthcare evidence ecosystem (VITALITY Study I): retrospective cohort study
Objective To investigate the impact of retracted trials on the production and use of healthcare evidence in the evidence ecosystem. Design Retrospective cohort study based on forward citation searchi...
bmj.com
Updated @iasp.bsky.social NeuPSIG systematic review & guideline for treatment of neuropathic pain now published in @thelancetneuro.bsky.social. A privilege to contribute to this project, brilliantly led by @nadiasoliman.bsky.social doi.org/10.1016/S147...
Redirecting
doi.org
Inclusion of Retracted Studies in Systematic Reviews and Meta-Analyses of Interventions jamanetwork.com/journals/jam...
Inclusion of Retracted Studies in Systematic Reviews and Meta-Analyses of Interventions
This systematic review and meta-analysis identifies reports of systematic reviews that included retracted studies in their meta-analyses, and assesses the impact of these retracted studies on the resu...
jamanetwork.com
File under “Never take the company’s word for it” www.thelancet.com/journals/lan...
Misleading marketing claims fuel tapentadol prescriptions
German drugmaker Grünenthal pushed its latest opioid as a safer option. People around the world got hooked. Madlen Davies, Hristio Boytchev, and Rafael Cabrera report.
thelancet.com
What are the benefits and harms of antidepressants for low back pain and spine‐related leg pain? Find out in our Cochrane review, published today: doi.org/10.1002/1465...
Antidepressants for low back pain and spine‐related leg pain - Ferraro, MC - 2025 | Cochrane Library
Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.
doi.org
Fantastic to make the front cover of @journalofpain with the featured article “Enhancing the trustworthiness of pain research: A call to action” www.jpain.org/article/S152... It’s open access so get downloading!
Great article on the launch of our new Center to End Corporate Harm at @ucsf-prhe.bsky.social by @lizagross.bsky.social Through empirical investigations, our work will aim to prevent the leading risk factor for death and disease globally. bit.ly/434MfqU
Lethal Greed: How Corporate Manipulation of Science and Regulation Makes People Sick - Inside Climate News
Scientists launch a new research center to study what they say is now a leading disease risk factor: corporations.
bit.ly