“you not only are the product — yes, they will steal and sell your data — but you are also robbed of learning. When the hype inevitably dies down, as it has done many times before, through AI summers and winters (…), you want to have skills. You want to have a degree that matters.”

Olivia Guest · Ολίβια Γκεστ@olivia.science · 3w ago

also olivia.science/cheating

Wie schlimm war die #Hitzewelle Ende Juni hierzulande? Ich habe das Gefühl, die Berichterstattung wird dem bislang nicht gerecht. Vielleicht hilft dieses Diagramm? Das sind die Sterbefälle für jeden Tag seit Anfang 2020 – in Rot die Kurve für 2026. https://datawrapper.dwcdn.net/gvL9c/1/

Ich stelle mir die Zukunft mit umfassender KI-Nutzung genau so vor, etwa so wie die Deutsche Bahn heute. Im Großen und Ganzen funktioniert alles, meistens jedenfalls, aber schlechter, als es müsste. Immer wieder ist man der Verzweiflung nahe, oder einfach nur fürchterlich genervt. Neuer Newsletter:

Das hier wäre fast ein Anti-KI-Manifest geworden, aber ich schreibe keine Manifeste

Die entscheidende Frage lautet: Rechtfertig der Nutzen den Preis?

open.substack.com

Here's v1.0 of my data science script 🚀 Last week of my introduction to #datascience course this semester. I used this as another chance to reiterate, improve, expand my teaching materials. The entire course material --> florian-huber.github.io/data_science... #oer #openscience #python #teaching

Our fingerprint analysis work has now been published 🎉 --> link.springer.com/article/10.1... Also check out our small helper library #chemap --> github.com/matchms/chemap (work together with @julianpollmann.bsky.social) #cheminformatics #openscience #Python

Count your bits: fingerprint benchmarking to assess broad chemical space representation - Journal of Cheminformatics

Quantifying molecular similarity is a cornerstone of cheminformatics, underpinning applications from virtual screening and nearest-neighbor search to chemical space visualization and the evaluation of...

link.springer.com

Another round of edits on my "Hands-on Introduction to Data Science" book. Finally managed to add a bit more explanatory text and figures on UMAP in the dimensionality reduction chapter. --> florian-huber.github.io/data_science... #OpenScience #teaching #python #datascience #oer

Working on another iteration of my #DataScience introductory course; Revising/expanding materials and new figures and illustrations. Here is a new sketch to display the rich data science skills landscape (not meant to be exhaustive). --> The book: florian-huber.github.io/data_science...

New MS2DeepScore release (2.9.0) 🚀 --> github.com/matchms/ms2d... The main change is the ability to use count and log-count rdkit fingerprints, as well as unfolded fingerprints for training. #opensource #massspec #Python

Could social media make us less polarized instead of more? We tested 5 algorithms on 3 platforms with 10,000 people for 6 months during the 2024 election, and found that the answer is yes. 🧵

Free registration for the 2026 #RDKit UGM (both in-person and online attendance) is now open: www.eventbrite.com/e/1985889262...

15th RDKit UGM 2026

2026 RDKit User Group Meeting (in person and online)

eventbrite.com

NEW: Wikipedia has banned AI-generated content.

Wikipedia Bans AI-Generated Content

“In recent months, more and more administrative reports centered on LLM-related issues, and editors were being overwhelmed.”

404media.co

Yet another example of why too much wealth means too much power. Remaining billionaire should fiscally not be possible. www.nytimes.com/2026/03/22/w... #taxtherich

The Billionaire Funding France’s Far Right

nytimes.com

Heute war der Startschuss eines tollen Projekts. Es heißt „Abpflastern“ und kam 2025 aus den Niederlanden nach Deutschland. Es ist ein Wettbewerb zwischen Städten und Gemeinden. Wer vom 21. März bis 31. Oktober am meisten Flächen entsiegelt & begrünt, gewinnt. Mitmachen können Privatpersonen...(1/2)

Our new paper on the presence of xenobiotics in marine dissolved organic matter just come out. Thanks to Jarmo Kalinski and our awesome collaborators, we were able to reanalyze more than 20 public LC-MS/MS datasets from seawater and ask how many anthropogenic compounds we can detect. rdcu.be/e8q6C

www.linkedin.com/posts/jjjvan...

#metabolomics #massspectrometry #networking #embedding #proudpi #compmetabolomics #bioinformatics | Justin J.J. van der Hooft

Many congrats 👏 🎉 🙌 to Niek de Jonge for initializing the concept of MS2DeepScore 2.0 😎 Please read Niek's post for all the innovations and updates we made - most importantly, this brings the combine...

linkedin.com

MS2DeepScore 2.0 is finally published 🚀 --> www.nature.com/articles/s41... This was a great journey with Niek de Jonge and a great team of collaborators! See more on LinkedIn: www.linkedin.com/posts/f-hube... #massspec #cheminformatics #ML #opensource #openscience #python

Bit ironic that we cannot name the new generation (of humans) GenAI because even that term is already taken by AI.

And @vestager.bsky.social takes the stage at #Rebuild. She's talking about digital infrastructure: "That's not a tech problem. That's a democratic problem." It's amazing to finally hear this said by someone with voice.

Just updated our preprint on benchmarking molecular fingerprints! --> www.biorxiv.org/content/10.1... Some key points - Count fingerprints should be the default (not binary!) - Unfolded fingerprints are often worth it. - Larger radius Morgan or FCFP fingerprints are good first bets.

Das bayerische Finanzministerium will weiterhin Microsoft-Produkte einsetzen und dafür einen millionenschweren Vertrag verlängern. Die Opposition will eine Abkehr vom Tech-Riesen und fordert „digitale Souveränität“. Doch auch das könnte sich als Bumerang erweisen. netzpolitik.org/2026/bayeris...

Bayerischer Landtag: Streit um Microsoft eskaliert

Das bayerische Finanzministerium will weiterhin Microsoft-Produkte im Freistaat einsetzen und dafür einen millionenschweren Vertrag verlängern. Die Opposition will eine Abkehr vom Tech-Riesen und ford...

netzpolitik.org

This is an excellent analogy, because my recollection from grade school is that the pen on the right looks fun and exciting, and then you play with it for a few minutes and realize it's not actually useful for anything and in fact makes some tasks more cumbersome, and never think about it again.

@marykmac.bsky.social · 8mo ago

yeah, just out of interest, how many people choose the pen on the right for real work or art? See a lot of them in professional workplaces, do you?

The Danish Ministry of Digital Affairs is moving away from Microsoft and switching instead to Linux and LibreOffice www.heise.de/news/Von-Wor...

Abschied bis Herbst: Dänisches Digitalministerium kehrt Microsoft den Rücken

Beim dänischen Digitalministerium sollen alle Angestellten ohne Microsoft auskommen. Stattdessen werde man Linux und LibreOffice nutzen, sagt die Ministerin.

heise.de

Considering I again did not receive the Nobel Prize for Economics, I no longer feel an obligation to pay back my debts.

I sometimes wonder how many more signs we (Europeans) need before we go all-in on European-based digital infrastructure. Well, here is yet another report telling us why we shouldn't feel too comfortable when fully relying on US-based services: www.linkedin.com/posts/f-hube... #DigitalSovereignty

Not my core expertise, but nonetheless also my (and most people's) business: Dependency on non-European digital services and infrastructure. Two days ago, the German Federal Ministry of the Inter...

Not my core expertise, but nonetheless also my (and most people's) business: Dependency on non-European digital services and infrastructure. Two days ago, the German Federal Ministry of the Interior ...

linkedin.com

I had a fantastic short trip to @w-u-r.bsky.social at the end of November. First, to attend and celebrate the PhD defense of Niek de Jonge and second, to join the Mini-Symposium organized by @jjjvanderhooft.bsky.social ! See more on LinkedIn: www.linkedin.com/posts/f-hube...

#matchms #ms2query #ms2deepscore | Florian Huber

I had an inspiring short trip to Wageningen University & Research at the end of November. First of all, to attend (and then celebrate!) the PhD defense of Niek de Jonge, and second, to join the Mini-S...

linkedin.com

Out now! xcms in Peak Form: Now Anchoring a Complete Metabolomics Data Preprocessing and Analysis Software Ecosystem doi.org/10.1021/acs.... with Phillipine and @jorainer.bsky.social (EURAC), @metabomichael.bsky.social, Hendrik and Norman from @ipbhalle.bsky.social, @janstanstrup.bsky.social, et al.

xcms in Peak Form: Now Anchoring a Complete Metabolomics Data Preprocessing and Analysis Software Ecosystem

High-quality data preprocessing is essential for untargeted metabolomics experiments, where increasing data set scale and complexity demand adaptable, robust, and reproducible software solutions. Modern preprocessing tools must evolve to integrate seamlessly with downstream analysis platforms, ensuring efficient and streamlined workflows. Since its introduction in 2005, the xcms R package has become one of the most widely used tools for LC-MS data preprocessing. Developed through an open-source, community-driven approach, xcms maintains long-term stability while continuously expanding its capabilities and accessibility. We present recent advancements that position xcms as a central component of a modular and interoperable software ecosystem for metabolomics data analysis. Key improvements include enhanced scalability, enabling the processing of large-scale experiments with thousands of samples on standard computing hardware. These developments empower users to build comprehensive, customizable, and reproducible workflows tailored to diverse experimental designs and analytical needs. An expanding collection of tutorials, documentation, and teaching materials further supports both new and experienced users in leveraging broader R and Bioconductor ecosystems. These resources facilitate the integration of statistical modeling, visualization tools, and domain-specific packages, extending the reach and impact of xcms workflows. Together, these enhancements solidify xcms as a cornerstone of modern metabolomics research.

doi.org

Relaunch unserer Vortragsreihe "ZDDenkanstöße". Zum Start mit Sabrina Großkopp --> www.linkedin.com/posts/zdd-du... Über die nächsten Wochen folgen weitere Vorträge: zdd-duesseldorf.de Kommt gerne vorbei!

Digi-Health Heroes - die Zukunft digitaler Gesundheit | Zentrum für Digitalisierung und Digitalität (ZDD)

Die ZZDenkanstöße gehen in die nächste Runde! Ab jetzt laden wir wieder wöchtenlich dazu ein, vor Ort oder online, unsere Forschenden und Projekte am ZDD kennenzulernen und über Themen der Digitalen T...

linkedin.com

Super useful new feature! I've started to recommend plotnine to everybody who does data analysis in python and needs a plotting solution, so this is very welcome.

Posit@posit.co · 10mo ago

Announcing Plotnine 0.15.0: The Python package for Grammar of Graphics gets a massive upgrade! A new feature is Native Plot Composition: combine multiple independent plots into one figure, no more layout managers for multi-panel #Python graphs! Read the post: posit.co/blog/plotnin...

Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon. blog.genesmindsmachines.com/p/we-still-c...

We still can’t predict much of anything in biology

Biology is hard. Yes, even for AI.

blog.genesmindsmachines.com

Impressive milestone by @europarl.europa.eu to ban "veggie-burger" and other great dangers to humanity. 100 millions of confused meat-eaters can now finally navigate the menus again.