Megan A Rech, PharmD, MSc

@meganarech.bsky.social

Wife & boy mama 👦👦| Research health scientist | EM pharmacist 🚑 | Co-founder empharmnet.org | Inaugural chair AEMP 🚨 (SAEM.org/AEMP)

Thanks for having me on to talk about the role & evolution of EM pharmacy. I'm grateful for the chance to thoughtfully debate & elevate our profession on EMCrit! Also got to shout out @saemaemp.bsky.social If you don't have an EM pharmacist, give this a listen to find out why you should!

EMCrit Blog and Podcast@emcrit.bsky.social · 5mo ago

EMCrit 421 - A Friendly Debate on the Role of ED Pharmacists - I want their minds, not their hands! with @MeganARech #EMPharmacy #EMRX Listen and then tell us what you think! emcrit.org/421

💡 Need one more reason to love your friendly EM pharmacist? Check out this #EMPHARM_NET SR/MA: ⏰ EMP presence was associated with reduced mean DTN time by 14.6 minutes (95 % CI -18.1, −11.1 min) Time for #AmericanStrokeAssociation to take notice?

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Kevin Mercer, PharmD, MPH@ohsnapimginger.bsky.social · 12mo ago

Just published in #AJEM! 📄 #PhAST1 is the first systematic review & meta-analysis quantifying the impact of #EMPharmD on stroke #doortoneedle times 🧠🚑 Faster treatment = better outcomes A huge win for interprofessionalism and solid case for EM pharmacist expansion! doi.org/10.1016/j.aj...

📣Have you heard of antiamyloid therapies for Alzheimer’s disease? They cause ADEs called ARIAs that are non-specific, typically require MRI, & can mimic stroke ⛔ Concomitant thrombolytics/anticoagulants are contraindicated Learn more in our JAMA IM Clinical Insight 👇

JAMA Internal Medicine@jamainternalmed.com · 12mo ago

Antiamyloid therapies for #Alzheimer disease slow cognitive decline but pose serious adverse effects like amyloid-related imaging abnormalities. ja.ma/3V32mjt

JAMA Internal Medicine presents: "New Frontier, New Challenges—Recognizing and Managing Adverse Effects of Antiamyloid Therapies" by Megan A. Rech, et al. Published online June 23, 2025.

Real-🌎 data in Veterans with fXaI-related ICH treated w/ andexanet alfa (AA; n=129) or 4F-PCC ( n=221) 🔷Propensity matched 🔷No difference in 90-day mortality 🔷⬆️30-day thrombotic events w/ AA (11.4 % vs. 2.4 %, p < 0.01) Free 👉https://www.sciencedirect.com/science/article/pii/S073567572500498X

Andexanet alfa increases 30-day thrombotic events relative to four-factor prothrombin complex concentrate for factor Xa inhibitors-related intracerebral hemorrhage in veterans

Two hemostatic agents are commonly used to reverse factor Xa (fXa) inhibitor-related intracranial hemorrhage (ICH): andexanet alfa (AA) or 4-factor pr…

sciencedirect.com

📣Have you heard of antiamyloid therapies for AD? They cause ADEs called ARIAs that are non-specific, typically require MRI & can mimic stroke ⛔ Concomitant thrombolytics/anticoagulants are contraindicated Learn more in our JAMA IM Clinical Insight 👉 jamanetwork.com/journals/jam...

Recognizing and Managing Adverse Effects of Antiamyloid Therapies

This clinical insight discusses the diagnosis and management of adverse effects of antiamyloid therapies and what medications require consideration or avoidance.

jamanetwork.com

Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.