Mélanie Laurin

@melanielaurin.bsky.social

Assistant professor, Faculty of Medicine - Université Laval Principal investigator, CHU de Québec - Université Laval Research Center (Elle/She-Her)

SAVE THE DATE for the 13th Canadian Developmental Biology Conference — March 7–10, 2027 — bringing together researchers, trainees, and innovators in developmental biology from across Canada and beyond.

Bild

Excited to share that our new open access review is out today: “Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities.” This work was led by Amy Beaudin, a PhD student in the lab, who did an excellent job synthesizing a rapidly evolving field.

Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities

Abstract. Intrinsic and adaptive resistance to therapy remain major barriers to effective cancer treatment. Diverse resistance mechanisms, including epithelial-mesenchymal transition, enhanced toleran...

portlandpress.com

Very proud to share our latest work, carried out with remarkable dedication by Léa and Claire. Thanks to JCS for the Highlight, but also the wonderful First Author profile featuring Léa and Claire, as well as the journal cover showcasing the work.

Journal of Cell Science@jcellsci.bsky.social · 5mo ago

Léa Marpeaux, Claire Baudouin, Gregory Emery @emery-lab.bsky.social and colleagues @umontreal.ca identify an apical supracellular actin network in epithelial cells that acts as a long-range force transmission device. journals.biologists.com/jcs/article/... journals.biologists.com/jcs/article/...

100% -- I can't even begin to calculate the lost productivity for those thousands of researchers applying over and over again in a desperate bid to keep their labs afloat

Paola A. Marignani@pmarignani.bsky.social · 6mo ago

13% success rates at #CIHR, is a really 87% fail rate for>4000 scientists. At a time when 🇨🇦 is investing millions to recruit more scientist into a broken funding environment. 🇨🇦, U need a strong science foundation 2 attract success. #CIHR, fix your science foundation, it is eroding in real time

I want to highlight the remarkable experience we had with the PLOS Biology editorial team. Their professionalism and genuinely constructive communication made an enormous difference, especially for an ECI navigating the publication process 😅 . This level of support truly matters.

PLOS Biology@plosbiology.org · 7mo ago

During embryogenesis, how do cells self-organize to support tissue-specific functions? @melanielaurin.bsky.social &co show that ARHGEF3 regulates #cadherin patterning & #placode polarization in early #HairFollicle development, influencing #morphogenesis @plosbiology.org 🧪 plos.io/450aBm5

The image depicts P-cadherin levels at cell–cell junctions in a planar view of whole-mount preparation of embryonic mouse skin. The image was derived from confocal microscopy data and artistically enhanced for visual clarity. Image credit: Krithika Kalyanakrishnan and Alexandra Jetté

Hey Bluesky friends, just wanted to give you a quick heads-up—my X (formerly Twitter) account was compromised at the begining of 2025. Big thanks to everyone who reached out to check in! I hadn't realized it sooner since I deleted the app a while back. Appreciate all the concern for my sanity 😉🤯😵‍💫