Merridee Lefner

@merridee.bsky.social

Postdoc studying the neurobiology of behavioral flexibility in the Moghaddam lab @OHSU 🧠 PhD from the Wanat lab @UTSA

Our new study ⬇️inspired by the question: does psilocybin influence meta-learning and cortical processing of unexpected uncertainty? Why is this important? Meta-learning may be critical for therapeutic effects of psychedelics and how the trip creates a window that facilitates clinical intervention

Don't miss this if you are going to #SfN2025 and interested in cross-species psychedelic neuroscience research Looking forward to hearing the talks and the discussions, and excited about presenting some of the lab's unpublished data and how we are thinking about future research

Katharina Schmack @kathaschmack.bsky.social · 12mo ago

Excited to speak in San Diego on Nov 14 at this SfN Sattelite! If you're curious about cross-species approaches to #psychedelics, #hallucinations and #consciousness, join us! 🐀👤🧠 Limited spots, register here: hopkinspsychedelic.org/sfn2025

New lab paper by @merridee.bsky.social identifying a novel role for VTA GABA neurons in behavioral flexibility GABA, but not dopamine, neuron activation correlates with behavior when cues unexpectedly shift from predicting punishment to predicting reward www.sciencedirect.com/science/arti...

Flexible updating of reward and punishment contingencies by VTA GABA neurons

In dynamic environments where stimuli predicting reward or punishment unexpectedly change, it is critical to flexibly update behavior while preserving…

sciencedirect.com

Yeah dopamine encodes reward but what about when contingencies shift and behavior needs to be flexible? Turns out VTA GABA neuron activity plays a role, check it out in my first postdoctoral research article here!👇

Bita Moghaddam@bita137.bsky.social · last yr.

New lab paper by @merridee.bsky.social identifying a novel role for VTA GABA neurons in behavioral flexibility GABA, but not dopamine, neuron activation correlates with behavior when cues unexpectedly shift from predicting punishment to predicting reward www.sciencedirect.com/science/arti...

Can confirm that my NSF grant "How False Beliefs Form & How to Correct Them" was cancelled today because it is "not in alignment with current NSF priorities" Shocking that understanding how people are misled by false information is now a forbidden topic. Our work will continue but at a smaller scale

Rebekah Tromble@rebekahtromble.bsky.social · last yr.

NSF has posted an “update on priorities.” They’re canceling all “DEI and misinformation/disinformation” grants. And the guidance on how to fulfill the longstanding, legally mandated Broadening Participation requirement is utterly incoherent. www.nsf.gov/updates-on-p...

The NIH diversity supplement pages have all been pulled down. What is a diversity supplement and why should the public care? A diversity supplement is funding to help diversify the research workforce. You may be wondering, “so what?”. Let me explain. www.nigms.nih.gov/Pages/PageNo...

National Institute of General Medical Sciences

NIGMS supports basic research to understand biological processes and lay the foundation for advances in disease diagnosis, treatment, and prevention.

nigms.nih.gov