A special #3DThursday: cleared human embryos showing the developing cerebral vasculature in 3D. 🔬 @miltenyibiotec.bsky.social Blaze #LSFM + iDISCO+ 🥼 Shotar et al. 📝 Journal of Anatomy (2026) 🏛️ Institut de la Vision, Paris 🎬 #syGlass v2.2.1+ @alainchedotal.bsky.social @sorbonne-universite.fr

Our first big push into hardware! Shipping software is relatively easy -- manufacturing delays and shipping physical hardware has a lot of logistics, but I'm really happy with our first move into supplying the world with cutting-edge visualization tools.

Brandy A Freitas@brandy-syglass.bsky.social · 3mo ago

This #3DThursday, our first syGlass 6DOF stylus kits are heading to researchers around the world! Built with #Antilatency after a lot of development and testing, the high-precision tracking lets you move, slice, annotate, and analyze 3D data naturally on the #Sony SRD. 🖊️📺 #syGlass #Microscopy

Mouse spine data #3DThursday from our partners at 3i! 🎉 Specimen from Pantelis Tsoulfas, imaged at #LSFM26 on 3i’s AxL light sheet. Axial sweeping helps preserve whole-spine context while improving optical sectioning across a thick cleared specimen. #syGlass @the.3i.social @univmiami.bsky.social

I am beaming with pride! Congratulations to Brandy and the entire syGlass team!

Brandy A Freitas@brandy-syglass.bsky.social · 6mo ago

We won! 🏆🥹 syGlass took Best Emerging XR Startup + Best Applied XR Product at #HarvardXR this weekend. Best part (besides surviving the pitch 💀) was live demos on the #Sony Spatial Reality Display, including this #microCT of a chameleon embryo from R Diaz More soon 👀 #XR #3DVisualization #syGlass

#UMAP in VR for #3DThursday! In this zebrafish embryogenesis dataset, RNA-seq + ATAC-seq across 94k+ cells reveal changing regulatory programs over time. 🥼 Yang-Joon Kim, Loic Royer @loicaroyer.bsky.social , Matthias Haury 📝 www.biorxiv.org/content/10.1... 🏛️ Biohub @biohub.org 🎬 #syGlass v2.6.0

Fun #3DThursday update: #syGlass now supports the #Sony Spatial Reality Display! 🎉📺 Glasses-free 3D—no headset needed. Just walk up, look, and see depth instantly. A powerful new way to share scientific data with researchers, students, and the public. #3DVisualization #SciComm #EdTech

☘️ A special #3DThursday for St Patrick's: Beer foam evolving in 4D in a microCT! 🍻 This is a Belgian Duvel (sorry not Irish...) from @tescan.bsky.social + Wesley De Boever Who’s off to #FOM2026 in Stockholm? I'll be there next week! www.focusonmicroscopy.org #Microscopy #MicroCT #Imaging #syGlass

Streaming OME-Zarr data directly into syGlass for #3DThursday🌍🔬 With #syGlass v2.6.0, datasets can stream from disk, S3, or HTTPS with no massive downloads required. Huge thanks to the community building open imaging standards: @openmicroscopy.org #OMEZarr #Microscopy #OpenScience #Bioimaging

The fruit fly of plant science for #3DThursday! 🌱 #ModelOrganism 🔬: #microCT, Zeiss @zeiss-microscopy.bsky.social Versa 520 XRM (contrast-enhanced with OsO₄) 🌱: Arabidopsis thaliana 🥼: Keith Duncan @cygnusplantxray.bsky.social 🏛️: Danforth Center @danforthcenter.bsky.social 🎬: syGlass.io #syGlass

New in syGlass for #3DThursday: a VR surface brush for editing meshes🖌️Here, I’m isolating a component from a @lumafield.bsky.social #microCT scan of a VR headset, painting partitions directly onto the surface and exporting clean .OBJs: v2.6.0 #VR #3DVisualization #syGlass #ScientificVisualization

We had a great time sharing 3D data from our pipeline at the Massachusetts Life Sciences Center's Convening of the Cores! Thanks to Sony and syGlass for making our data pop on the Spatial Reality Display. MA researchers, check out LifeCanvas tools at cores near you: bit.ly/3O8SgO0

❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ. 🔬: Miltenyi Ultramiscroscope 🥼: Pam Rios Coronado, @pamrc.bsky.social 🏛️: Red-Horse lab @stanford.edu 🎬: #syGlass

Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples. #MedicalImaging #3DImaging

The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass! @alleninstitute.org #3DThursday #DataViz #VR

For #3DThursday, a skeleton shrimp imaged on a Flamingo light sheet microscope — a modular, traveling #LSFM built to bring the microscope to the biology.🔬🦩Fast 3D imaging, low phototoxicity. 🥼: Carsten Wolff @carsten-wolff.bsky.social 📝: huiskenlab.com/flamingo/ 🏛️: @morgridgeinstitute.bsky.social

🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm 🔬: Bruker SkyScan 1172 🏛️: UWyoming 🎬: #syGlass, v2.5.0

2025 took us around the world 🌍 From Zurich to Beijing, London, Paris, Montreal, all over the Americas, we explored scientific datasets in VR with the researchers who created them -- and pushed #syGlass to new limits for 3D analysis. On to 2026. 🔬✨ #3DThursday #Microscopy #ScientificImaging

Nice feature from NVIDIA on #syGlass at the MBL! Exciting to see AI, RTX GPUs, and VR coming together to explore massive 3D brain datasets, with high school students contributing to ongoing, cutting-edge neuroscience research. @mblscience.bsky.social blogs.nvidia.com/blog/mbl-hum...

Marine Biological Laboratory Explores Human Memory With AI and Virtual Reality

The lab in Massachusetts is studying molecular mechanisms of human memory function powered by NVIDIA RTX GPUs, HP Z Workstations and virtual-reality technology.

blogs.nvidia.com

#syGlass v2.5.0 is out! 🎉 New depth-aware colormaps, expanded file formats (NRRD/MRC/TCF/OME-Zarr v3), better #VR segmentation tools, and upgraded narration workflows — all focused on making #3Ddata easier to explore and share. Blog: www.syglass.io/blog/syglass... #Microscopy #Imaging #3DThursday

Guest lectured at UNH–Manchester’s Techniques in Microscopy this week, and the students are already thinking like researchers. Early exposure to real #Microscopy and #ImageAnalysis tools makes all the difference. 🔬: Zeiss LSM 510 🥼: Students + Prof Mark Scimone 🎬: syGlass.io #3DThursday #syGlass

One year of #3DThursday! Revisiting our first specimen, a Pekin duck: thanks to this community we learned she was Beaker, a rescued duck from Utah who later contributed to science. 🔬: #CTScan, Scarlet Imaging's BriteVu 🥼: Scott Echols 🎬: syGlass.io 🦆📸: credit TIFOtter #Anatomy #syGlass #SciComm

Stoked to be back in San Diego for #sfn25 with syGlass and the rest of the team. This week, we're showing off our new AI based axon tracer and the new Sony Spatial Display. Come visit us at booth 813!

Exciting News! 😎 syGlass is proud to announce our new collaboration with Sony, featuring their revolutionary glasses-free 3D Spatial Reality Display. Experience the future of visualization at the 2025 Society for Neuroscience conference. Stop by our booth #813 to see it in action! #sfn25 #sfn2025

For #3DThursday we’re introducing Dynamic Depth color mapping! It encodes distance with smooth depth-aware gradients so layered structures pop without losing context. 🔬 #MicroCT of a P1 mouse 🥼 Hsu Lab, Baylor, @cwloganhsu.bsky.social 🎬 syGlass.io #Microscopy #SciComm #3DVisualization #syGlass

Expansion with Magnify for #3DThursday this week! This mouse brain tissue was imaged using Magnify Biosciences, Inc. expansion microscopy — a simple, low-cost way to achieve nanoscale resolution with a standard confocal.

it was great to present syGlass, Inc at CACIE, part of the largest international educational conference in China, with Kenan Sener, Ed.D. Very grateful for CAEIE for hosting me for this week in Beijing. ❤️ lnkd.in/g8KQMa8x

Taking over #3DThursday while Brandy Freitas @brandy-syglass.bsky.social is out of office for some adventures! 🦇: Rousettus aegyptiacus stained in 10% Lugol’s iodine for 3 months 🔬: PerkinElmer Quantum GX microCT 🥼: @acsharp.bsky.social 🏛️: University of Liverpool’s Centre for Preclinical Imaging

Absolutely amazing to hike the Great Wall of China. Truly an engineering marvel and an amazing historic achievement.

It's great to visit my good friend Alain Chédotal for an extra special lecture of tissue clearing and light sheet microscopy -- at Faculté de Médecine Lyon Est, Université Claude Bernard Lyon 1 + Hospices Civils de Lyon - HCL @hospicescivilslyon.bsky.social

The #mesoSPIM symposium really opened my eyes to the power of open source hardware. I've highlighted some of the surprising outcomes in a new blog post: How Open Source Microscopy is Solving the Funding Crisis: Insights from the mesoSPIM 10-Year Symposium www.syglass.io/blog/how-ope...

How Open Source Microscopy is Solving the Funding Crisis — syGlass

Insights from the mesoSPIM 10-year symposium, as reported by Michael Morehead, the CEO of syGlass.

syglass.io

Brandy A Freitas@brandy-syglass.bsky.social · 11mo ago

The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery. #Microscopy #Lightsheet #syGlass