Super exciting study linking diet to Colibactin producing bacteria and its impact on CRC. Check out our MOTM highlight on this at cmmc.gnps2.org or bsky.app/profile/microbialcmmc.bsky.social/post/3lnnjphdu3c2o

Cancer Therapy Advisor@cancertherapyadv.bsky.social · last yr.

Exposure to colibactin-producing bacteria in the first decade of life may be contributing to the rising incidence of early-onset #CRC, research suggests. #crcsm shorturl.at/GRKEW

Thanks to all our lovely collaborators for this accomplishment!

We are back again with the April Molecule of the month featuring Colibactin! Check out more at cmmc.gnps2.org

Great introduction to the PODP with a highlight on making data public and usable 😊

Justin J.J. van der Hooft@jjjvanderhooft.bsky.social · last yr.

The #NPLinker eScience #workshop 2025 finished today with setting the scene for tomorrow morning with Pairing the Omics led by Laura Rosina Torres Ortega & myself! 😎 The Paired Omics Data Platform and various flavours of linking omics data were discussed. #PoDP #NPLinker #NPOmix

Happy March! While there’s so much to say about our friendly neighborhood Riboflavin, here we show some highlights. It’s amazing how we can engineer bacteria for commercial production! Check out more at cmmc.gnps2.org

got microbial metabolites? Add to the public knowledgebase available through GNPS2! cmmc.gnps2.org

Was great to see this AMAZING talk by Robert Quinn of @quinn-labs.bsky.social here at UCSD. This talk included a history of the discovery of amine conjugated bile acids, the enzymology behind them, and their impact on health and disease. Some featured papers in his talk shared below:

How does metabolomics help agriculture? Human health? A brief overview of this fungal metabolite-Fumonisin B2- shows the importance of this overlap. Check out more at cmmc.gnps2.org Another impactful study of this metabolite: pubs.acs.org/doi/full/10.1021/jf0718906

"How does kombucha impact the gut microbiome and health? 🧬🍵 Our new study explores this popular fermented tea's subtle effects on gut bacteria and biochemical markers in a Western diet context. Dive into the findings: www.nature.com/articles/s41...

Modulating the human gut microbiome and health markers through kombucha consumption: a controlled clinical study - Scientific Reports

Scientific Reports - Modulating the human gut microbiome and health markers through kombucha consumption: a controlled clinical study

nature.com

Wow—a probiotic Ozempic pathway? Free fatty acid receptor Ffar4 low in diabetic patients and mouse models, boosts sugar intake Ffar4 KO, microbiome, and metabolite study pinpoint how Bacteroides vulgatus and its metabolite pantothenate promote GLP-1 secretion Paper: www.nature.com/articles/s41...

A Review in Nature Reviews Microbiology explores the pathways linking the gut and the brain and examines the microbial, endocrine and neural mechanisms involved in the gut microbiota-brain axis and their impact on gastrointestinal and neuropsychiatric health. https://go.nature.com/3DSeS0d 🔒

Our latest publication suggests that there is a link between infant malnutrition, the microbiome, the plasma lipidome and cognitive function. Out now in @naturecomms.bsky.social #Lipidomics #TeamMassSpec www.nature.com/articles/s41...

Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition - Nature Communications

Here, using a multisystem approach, the authors characterize the impact of Moderate Acute Malnutrition (MAM) on the gut-brain axis and its effects on cognitive and microbiome development in one-year-o...

nature.com

An oldie but a goodie 😊 Interested in using the CMMC knowledgebase or contributing your data? Check out this workshop to learn how or see us at cmmc.gnps2.org

OUT NOW - Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection www.nature.com/articles/s41...

Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection - Nature Microbiology

A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.

nature.com

Really cool paper that expands our knowledge of combinatorial antibiotic interactions. Bacteria can become resistant to multiple antibiotics at the same time, but they ALSO can become sensitive to other antibiotics (trade-offs). #Microsky #vetmed #betterdatasavespets www.nature.com/articles/s41...

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics - Nature Microbiology

Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and ...

nature.com

Happy new year to all! We are back again with TWO featured metabolites. Check it out at cmmc.gnps2.org/molecule_month/

Big thanks to @microbialcmmc.bsky.social for the 1st hands-on webinar on reverse #metabolomics on 11 Dec 2024. @vincentlamoureux.bsky.social , Victoria Deleray, Helena Mannochio Russo, @shipei-xing.bsky.social , @pieterdorrestein.bsky.social

Welcome to CMMC! We are excited to announce our upcoming workshop designed to be interactive and beginner friendly. We will introduce Reverse Metabolomics, a novel approach to identifying microbial metabolites using mass spec. We will show YOU how to identify and categorize microbial metabolites!