Mithu Maheswaranathan, MD
@mithurheum.bsky.social
🩺 Rheumatologist at Duke School of Medicine 🎨 Creator of Rheum OnePagers 🧑🏽💻 Infographics • MedEd • Lupus • Health Literacy
🆕 Visual Abstract with Healio Rheum 🟢 Bone Marrow Edema (BME) in the General Population 💡Key Takeaway: BME is NON-specific, and was seen in up to *30%* of healthy people (N >11,000) 📝 Bressem et al, Lancet Rheum 🔗: tinyurl.com/BMEHealio #Rheumatology #RheumX #Radiology
🆕 Phase 3 RCT of #Brepocitinib (TYK2-JAK1 inhibitor) vs PBO in #Dermatomyositis (The VALOR Trial) 🔥 ⌛ Rapid onset: improvements as early as wk 4 💪 All pts had both active muscle + skin disease 📈 Improvement in myositis activity, GC tapering #Myositis #Rheumatology #DermSky #RheumSky #Dermatology
🆕 Visual Abstract with Healio Rheum 🟢 GLP1 Receptor Agonist Use in #PsoriaticArthritis • Ixekizumab (IXE; Taltz) + Tirzepatide (GLP1) was superior to IXE alone in improving PsA disease activity 📝: by Merola et al (A&R) 🔗: tinyurl.com/glp1psa #GLP1 #Rheumatology #RheumX
🆕 Visual Abstract w/ Healio Rheumatology 🟢 #Telitacicept in Systemic Lupus • telitacicept: TACI-Fc fusion protein which targets BLyS/APRIL • telitacicept: ⇡ response rate vs PBO 📖: van Vollenhoven et al, NEJM 📎: tinyurl.com/telitacicepthealio #Lupus #MedSky #RheumSky @gohealio.bsky.social
🆕 Approach to Rheum Labs! 🧪 With the current #rheumatology workforce shortage, better education is needed to increase yield of new patient referrals from referring clinicians: 1️⃣ Joint Pain: when should one refer to #Rheum? 2️⃣ ANA: when should an #ANA be checked? #MedSky #RheumSky #PositiveANA
🆕 2025 ACR Guideline for Treatment of Systemic #Lupus Erythematosus 🦋 Just Released: Nov 3 #ACR25 🔥 🔸Review organ-specific treatment recommendations 🔸Steroid & HCQ Use Guidance 🔸Management of Comorbidities ➠ Read the Full Guideline here: acr.tw/47mkegj #RheumSky #SLE #Rheumatology
That’s a wrap on #ACR25. Great to connect with the #rheumsky #meded community IRL! @davidleverenz.bsky.social @mithurheum.bsky.social @pedsrheum2connect.bsky.social @washumedrheum.bsky.social
🆕 Clinical Year in Review at #ACR25 By Dr. Bryant England @unmc.bsky.social 🔶 Review the most impactful studies in #Rheumatology from the past year! ❓ Any studies you would add to the list? #RheumSky #MedSky #YearInReview
🆕 Secrets & Pearls of #Rheumatology at #ACR25 | Part 1 by Dr. Janet Pope 🖐️ Cutaneous Pathology SLE/DM 🧴 Tips for SLE 💪 Cancer Screening in Myositis 🩸 Laboratory Testing 🥶 Raynaud's / Scleroderma 👀 Sjogrens Disease #RheumSky #MedSky #Lupus #Myositis #Scleroderma #Sjogrens
🆕 Collaboration with RheumNow 🔵 3-Part Series on Interstitial Lung Disease Part 2: Diagnosis & Subtypes of #ILD 👩🏻⚕️ What to look for on Physical Exam 🧪 Serologic Testing & Diagnostic Workup 🫁 Differentiating ILD Subtypes on Imaging #RheumSky #PulmSky #MedSky #InterstitialLungDisease
🆕 Behçet's Disease: Let’s explore this multi-system #vasculitis 💫 👄 Oral and Genital Ulcers 🩸 DVT, Arterial Aneurysm 👁️ Uveitis 🧠 Neurologic Involvement 🖐️ Cutaneous Disease / Pathergy #RheumSky #Behcets #Rheumatology
🆕 2024 ACR Guidelines for Screening, Treatment and Management of Lupus Nephritis 🫘 • Just Released: May 7, 2025 🔥 🔸 New Recommendations for Triple Therapy for Class III/IV + V Lupus Nephritis 🦋 🔸 Reduced ⇣ Dose of PO Steroids after IV Pulse! 💊 #LupusNephritis #RheumSky #NephSky #Lupus
🆕 PJP Prophylaxis in #Rheumatology 🫁 🔹Discuss risk factors for PJP infection 🔹Risk Stratify: CD4 count <200 or ALC <500 = ⇡Risk 🔹Review Treatment options and when to stop PPx? #MedSky #RheumSky #PulmSky #PJP
💫 Check out the new Rheum Madness x Rheum One Pagers bracket infographic! 🎉🏀📟 📖 Read most pivotal, innovative studies in #rheum in past 2 yrs 🎙️ Listen to the Rheum Madness podcasts 🏀 Submit Brackets before April 1 @rheummadness.bsky.social @davidleverenz.bsky.social @larneson.bsky.social
🆕 #Obinutuzumab (Obi) in Lupus Nephritis: the REGENCY Trial Phase 3 RCT: Obi vs PBO 🫘 Pts w/ SLE nephritis Class III/IV ± 5 🎲 Randomized 1:1 to OBI v PBO (+MMF/steroids) 📊 Obi: ⇡rate of renal response and improved renal outcomes #LupusNephritis #RheumSky #NephSky #MedSky #Lupus
🆕 Visual Abstract with Healio Rheumatology 🟢 🔥 New Therapy for IgG4-Related Disease: INEBILIZUMAB 💉 RCT of inebilizumab (anti-CD19) vs placebo 👥 Adult pts with IgG4-RD involving ≥ 2 organs 📊 Results:⇣flare rate,⇡remission #IgG4RD #RareDiseases #Rheumatology #Inebilizumab
Excited to have the opportunity to present on Physician #Burnout in Rheumatology at our division Grand Rounds today. Thankful many advocates have been voices on this important topic in our current healthcare climate & trend of physicians exiting clinical medicine!
#ACR24 Lupus Nephritis CARE • By Dr. Maria Dall'Era (UCSF) Review of #LupusNephritis 🫘 ▪️Rx TRIPLE therapy ▪️belimumab vs voclosporin ▪️low level proteinuria (even *UPCR <0.5*) can STILL be associated with disease activity (Class III/IV/V) #Lupus #RheumSky #NephSky
🆕 The Great Debate at #ACR24: Is Mixed Connective Tissue Disease (MCTD) a distinct disease entity? 🗳️ Final Vote (n=430 votes) • 51% = MCTD *is* a unique disease • 49% = MCTD is not a unique disease #MixedConnectiveTissueDisease #Rheumatology #RheumSky #MCTD
Clinical Year in Review at #ACR24 Presented by Dr. Michael Pillinger • Review some of the most impactful studies in Rheumatology from the past year! #MedSky #Rheumatology #RheumSky
Congratulations to @sjbracken.bsky.social & all the ACR Distinguished Fellow award recipients at #ACR24 🥇 Anyone who knows Sonali knows how dedicated and hardworking she is — from her research to patient care — working to improve the lives of patients with #scleroderma! #DukeRheum
Hi #MedSky 👋🏽 #FirstPost I’m Mithu, a rheumatologist who loves all things rheum & creating infographics to explain complex rheum topics! Hope to share more on systemic autoimmune diseases here! Excited to see this new community grow & for #ACR24 this week 🥳 #RheumSky #Rheumatology #MedEd
