Interested to know how #mtHsp70 looks inside #mitochondria and what that means for #mitochondrial #proteostasis and #stress #signalling? Take a look at our latest publication in @pnas.org 🥳🥳 @osman-lab.bsky.social doi.org/10.1073/pnas...
Mokranjac Lab
@mokranjaclab.bsky.social
Working on biogenesis and quality control of mitochondria.
Join us today (Wednesday, Nov 26) for a talk by Dejana Mokranjac from the Ludwig-Maximilians-Universität in Munich -she is going to present the latest results from her mitochondrial research. We are very much looking forward to her presentation! @mokranjaclab.bsky.social
Schreiner, Mikeladze-Dvali et al. @lifescimunich.bsky.social show that CDK-1 primes PCMD-1 for PLK-1 phosphorylation. Mutations in PLK-1 docking sites impair SPD-5 binding, destabilize the PCM, and delay #centriole separation. rupress.org/jcb/article/... #Centrosome #PCMstability #Celegans
New publication alert!!!🥳 We identified Pth2 as a peptidyl tRNA hydrolase in the mitoRQC pathway! Thank you to all the co-authors!! @cp-molcell.bsky.social @dfg.de @osman-lab.bsky.social @lmumuenchen.bsky.social doi.org/10.1016/j.mo... #Pth2 #mitochondria #mitoRQC #qualitycontrol
🏅We congratulate 🌟Nils Bertram🌟 @lmumuenchen.bsky.social, on winning a FEBS Letters #PosterPrize at the #EMBOFEBSproteostasis meeting, held in Espoo, Finland! 🎉👏👏👏 📸 Photo: Nils with our Managing Editor, Dr. Duncan Wright
Thank you for publishing our hardwork!!✨️ @emboreports.org
Dejana Mokranjac @mokranjaclab.bsky.social identifies a pathway for #oxidation and assembly of mitochondrial inner #membrane proteins involving Dbi1 as oxidoreductase and assembly #chaperone for #mitochondria inner membrane proteins. -> www.embopress.org/doi/full/10....
Congratulations to the team on this cool story!✨️
How does an unusual heptameric AAA-ATPase translocate fully-folded Rieske protein across the inner mitochondrial membrane? Cryo-EM & functional data by Roland Beckmann and coworkers show how Bcs1 alternates between different states during its translocation activity. www.embopress.org/doi/full/10....