I am thrilled to share our new article entitled 'Alternative splicing of SORBS1 affects neuromuscular junction integrity in myotonic dystrophy type 1 onlinelibrary.wiley.com/doi/10.1002/... @cecilemartinat.bsky.social

Alternative Splicing of SORBS1 Affects Neuromuscular Junction Integrity in Myotonic Dystrophy Type 1

Background Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disorder characterized by CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica protein kinase co...

onlinelibrary.wiley.com

So proud of Caroline Hermitte, a talented PhD student of our group in #I-Stem on winning the award for the best short presentation at the @fsscr.bsky.social meeting @morgangazzola.bsky.social

Unlike eggs & mitotic cells, in adherent interphasic cells the centrosome is NOT positioned by a balance of forces along #microtubules, but by cell shape organization around the #centrosome: rupress.org/jcb/article/... @lblanchoin.bsky.social @manuelthery.bsky.social @gelinmatthieu.bsky.social

I am thrilled to present for my first post in Bluesky my first preprint as a last author. Here we demonstrate that SORBS1 splicing misregulation impairs neuromuscular junction stability in humans, mice and zebrafish. www.biorxiv.org/content/10.1...

Alternative splicing of SORBS1 affects neuromuscular junction formation and stability in myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disease characterized by a CTG repeat expansion in the 3" untranslated region of the gene coding for the dystrophia myotonica protein k...

biorxiv.org