Michael Ratz

@mratz.bsky.social

Group Leader, Karolinska Institute, Sweden

Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms. We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.

Image of a coronal section through postnatal mouse somatosensory cortex (S1BF with transient expression of the serotonin transporter in thalamic afferents shown in red.

While I applaud Europe taking a step to fund bringing scientific excellence to Europe, the ERC’s current success rates at 10% for Europe based scientists is statistically at lottery levels. The total ERC budget should double across the board aiming at doubling funding rates.

Excited to share our paper with Jakobs Lab @mpi-nat.bsky.social on the in situ structure of the prohibitin complex in human mitochondria! Although mitochondria contain >1000 proteins, it seems a single, 2-subunit complex occupies 1-3% of the crista membrane area 🤯 www.nature.com/articles/s41...

In situ architecture of the human prohibitin complex - Nature Cell Biology

Lange, Ratz, et al. investigate the number and distribution of human prohibitin complexes in the mitochondrial inner membrane, uncovering their bell-shaped structure and assembly of alternating PHB1 a...

nature.com

Single-cell people! Check out the "Innovations in Single Cell Omics" meeting, May 12-13 in Berlin! I'm really looking forward to being a part of this great line-up and also to presenting a Night Science workshop. Join us! www.isco-conference.eu Abstract deadline for talks & posters: March 7

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