A ‘tour de force’! First description of human early telencephalon patterning & signalling centre dynamics, coupling transcriptomics & 4D gene expression imaging. ➡️ Human forebrain is distinct from mouse as soon at anterior neural plate closes. First @crick.ac.uk paper from @houartlab.bsky.social
Excited to share our new #preprint uncovering how early human forebrain is patterned. Compared to mouse, human dorsoventral and anteroposterior telencephalon patterning is strikingly delayed, which is correlated with SHH and FGF signalling differences. Read it here: www.biorxiv.org/content/10.6...