Centre for Developmental Neurobiology

@devneuro.bsky.social

Mechanisms of brain development. IoPPN, King's College London

A ‘tour de force’! First description of human early telencephalon patterning & signalling centre dynamics, coupling transcriptomics & 4D gene expression imaging. ➡️ Human forebrain is distinct from mouse as soon at anterior neural plate closes. First @crick.ac.uk paper from @houartlab.bsky.social

Afnan Azizi@stochastalive.bsky.social · 4mo ago

Excited to share our new #preprint uncovering how early human forebrain is patterned. Compared to mouse, human dorsoventral and anteroposterior telencephalon patterning is strikingly delayed, which is correlated with SHH and FGF signalling differences. Read it here: www.biorxiv.org/content/10.6...

Congratulations to the @aims2trials.bsky.social team who have been awarded a EURORDIS-Rare Diseases Black Pearl Award for Patient Engagement, for their commitment to involving patients as equal partners in research. 🏆 🧠 Read more here: lnkd.in/eiFDxQnq, as we mark this year's #RareDiseaseDay

EURORDIS-Rare Diseases Europe@eurordis.bsky.social · 5mo ago

✨ That’s a wrap on the 15th #EURPRDISAWARDS2026! Tonight in Brussels and online, we celebrated leaders driving change in the rare disease community. Congrats to all our awardees! 🎥 https://go.eurordis.org/BPA2026

🧠 Fascinating day at 2026 MRC CNDD symposium on how environment shapes neurodevelopment. 🌎 Inspiring talks on cannabis & psychosis, maternal COVID-19, influence of environment in autism & epilepsy, and immune–brain links, among more! 🎤Huge thanks to speakers, attendees and organisers!

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🌟 Join us for the MRC CNDD Symposium 2026! 🌟 🗓 Friday 13 February 2026 | 9:00 AM - 6:30 PM 📍 Great Hall, Strand Campus, London 🧠 Shaping the Brain: Environmental Influences on Neurodevelopmental Conditions 🧠 Reserve your spot and take a look at the exciting programme here: tinyurl.com/mu6mbe5p

MRC CNDD Symposium 2026

Shaping the Brain: Environmental Influences on Neurodevelopmental Conditions

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New organoid research with input from CDN's Benedikt Berninger shows that the “inactive” X chromosome in female brain cells can be dynamically reactivated during development, helping protect against X-linked neurological disorders. Take a look! 🧠 ♀️https://www.nature.com/articles/s41467-026-68428-x

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Congratulations to Dr Richard Taylor for being awarded the Race Against Dementia Fellowship 👏 🔗 Read more about the prestigious 5-year award and Richard's research into synapse resilience and neuroprotective mechanisms in healthy ageing and dementia: tinyurl.com/2s39mcma

CDNCDN - news-detail

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Research at ARUK@alzheimersresearchuk.org · 9mo ago

🚨Meet the latest early career researchers awarded Race Against Dementia Fellowships🚨 These rising stars are challenging old ideas and driving bold new approaches to speed up progress @RichardTaylor @sorayam.bsky.social @HelenRowland

Our Neureka! Seminar Series is back 🧠 We’re very pleased to welcome Professor Nicky Clayton from the University of Cambridge, who will be presenting the first seminar of the academic year, hosted by Alexi Mery. Join us at 1pm today in the Large Meeting Room to hear about her exciting research!

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@houartlab.bsky.social first time at the comparative neuro conference. Fantastic #ECCN2025 meeting! The mix of ‘old’ and new technologies brings the field a new edge and the potential for new understanding of brain evolutionary mechanisms. Exciting!

Roberto Toro@r3rt0.bsky.social · last yr.

Differences in neurogenesis across species appear since the earliest stages of development, as shows @cohouart.bsky.social #ECCN2025 @borrell-lab.bsky.social @k4tj4.bsky.social

Dkk genes dynamically expressed in the zebrafish nervous system, some in very discreet brain populations (watch this space for brain images). Malik Missaoui is using genetics to follow behaviour of endogenous proteins and crack their local functions. @mrc-cndd.bsky.social @kingsioppn.bsky.social

Houart Lab@houartlab.bsky.social · last yr.

🎣 Fishing for Dkk in #zebrafish 🎣 In the lab, PhD student Malik Misssaoui looks for the expression patterns of the dkk genes in zebrafish. Dkk proteins are modulators of wnt singalling, and changes in their expression levels have been linked to neurodegenerative diseases like Alzheimers.

9/10 In sum, our findings identify a previously unknown form of interneuron plasticity and strengthen the idea that neuropeptide signalling plays crucial roles in maintaining neural circuit stability. Funded by the magnificents @erc.europa.eu and Rosetrees Trust