🧵🧪 STOP-PKD study | Four additional trial sites activated The STOP-PKD study continues to expand its recruitment network across Europe, with four additional trial sites now initiated: three in Germany and a second centre in Austria.
Roman-Ulrich Müller
@muellerrom.bsky.social
passionate for translational research...kidney disease and beyond...
Unterstützung im Direktions- und Oberarztsekretariat gesucht! Eine herausragende administrative Organisation ist die Voraussetzung für eine wissenschaftlich starke Nephrologie an einem Universitätsklinikum. www.uniklinik-duesseldorf.de/ausbildung-k... www.uniklinik-duesseldorf.de/ausbildung-k...
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uniklinik-duesseldorf.de
Great opening for a professorship on data science in kidney disease and transplantation. Making the next steps towards targeted treatment in nephrology will largely depend on data science. Looking forward to working on this transition together with outstanding colleagues. bit.ly/3TlscBM
bit.ly
An expert-guided annotation loop reduced expert annotation time and enabled estimated cost savings while producing high-quality reference standard CT and MRI segmentations https://doi.org/10.1148/ryai.250200 @muellerrom.bsky.social #AI #ML #MachineLearning
An iterative training approach, the expert-guided annotation loop, for efficient reference standard medical image segmentation https://doi.org/10.1148/ryai.250200 @muellerrom.bsky.social #Segmentation #MRI #MachineLearning
An iterative training approach, the expert-guided annotation loop, for efficient reference standard medical image segmentation https://doi.org/10.1148/ryai.250200 @muellerrom.bsky.social #CostAnalysis #MRI #ML
An iterative training approach, the expert-guided annotation loop, for efficient reference standard medical image segmentation https://doi.org/10.1148/ryai.250200 @muellerrom.bsky.social #MRI #AI #ML
Interested in working on RNA-biology in human disease? We can offer a PhD student position in a great team. Looking into RNA-modifications as a driver of polycystic kidney disease together with @landthalerm.bsky.social www.jobvector.de/job/phd-stud...
PhD Student*in (m/w/d) | Job in Düsseldorf
Conducting innovative research in line with the above-mentioned project. Collecting, analyzing, and interpreting data using various OMICs techniques. Conducting in vitro and in vivo experiments. Colla...
jobvector.de
Impact on Cost and Expert Time of Data-Efficient Deep Learning for Medical Image Segmentation https://doi.org/10.1148/ryai.250200 @muellerrom.bsky.social #Segmentation #AI #MachineLearning
An expert-guided annotation loop reduced expert annotation time and enabled estimated cost savings while producing high-quality reference standard CT and MRI segmentations https://doi.org/10.1148/ryai.250200 @muellerrom.bsky.social #MRI #CT #ML
🧵 (4/4) 🌍 Please check the map available on the study website to identify the nearest participating centre. If you need any support or guidance, we would be very happy to support you or to connect you with your local patient association. @uniklinikkoeln.bsky.social @muellerrom.bsky.social
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🧵 🧪 STOP-PKD study | New recruitment sites Research on ADPKD continues to move forward: stop-pkd.de/en
We’re excited to share our latest publication in npj Aging on the molecular effects of short-term calorie restriction before living kidney donation. Using proteomics, lipidomics, and cytokine profiling, we found that just 7 days of 50% calorie restriction induced molecular signatures linked to: 🧵
The fact that primary hyperoxaluria is the first kidney disease for which an RNA therapeutic has become available is a milestone for the field. How does this change the treatment landscape? 🧵
🧵 🧬 ADPKD research needs your voice The future of ADPKD research is evolving — and patient perspectives are essential to guide this change.
🔬🩺 From bench to bedside Professor @olivercornely.bsky.social und Professor @muellerrom.bsky.social explain in the new #Unimagazin how Basic Research leads to medical Progress. Read more ▶️ uni.koeln/2VKJM #uniköln #unicologne #transationalresearch @cecad.bsky.social
🔬🩺 Aus dem Labor ans Krankenbett Wie aus Grundlagenforschung medizinischer Fortschritt wird erklären Professor @olivercornely.bsky.social und Professor @muellerrom.bsky.social im aktuellen #Unimagazin. Zum Artikel ▶️ uni.koeln/LHSE3 #uniköln #unicologne #transationalresearch @cecad.bsky.social
🧵 🧪 STOP-PKD study | Expanding recruitment across Europe: stop-pkd.de/en The STOP-PKD study continues to expand, marking an important step forward for ADPKD research in Europe.
I usually think twice before posting preprints. But this time it’s different. MEDA-PKD is the essence of our work over more than a decade — and, to me, one of the most meaningful contributions I’ve been able to make to biomedical research. 🧵
New publication on hereditary kidney tumors. Our questionnaire-based screening approach (referenced in the German giudeline) has now been validated. A step toward better identification of patients who may benefit from genetic evaluation and personalized care. 📖 academic.oup.com/ckj/advance-...
Hereditary kidney tumor syndromes: structured evaluation of a questionnaire-based approach
AbstractBackground. Up to 8% of renal tumors have a monogenic cause, yet hereditary renal cell carcinoma (hRCC) syndromes such as Von Hippel–Lindau (VHL),
academic.oup.com
ADPKD comes with increased risk of aneurysms. This manifestation comes concern, for both patients and MDs. Risk assessment? Screening? Treatment decisions? This ERA Genes&Kidney commentary provides fin-depth guidance based on the @kdigo.org ADPKD guideline. academic.oup.com/ndt/article/...
KDIGO 2025 Clinical Practice Guideline for ADPKD: a commentary on intracranial aneurysms and other vascular manifestations from the ERA Working Group Genes & Kidney
Abstract. The 2025 KDIGO Clinical Practice Guideline for Autosomal Dominant Polycystic Kidney Disease (ADPKD) addresses intracranial aneurysms (ICAs) and o
academic.oup.com
🧵 🧬 Help shape the future of ADPKD research Are you living with ADPKD? Your perspective matters. PKD International is part of the ARTICYST Project, a European initiative bringing together research centres and the patient community to improve the future of ADPKD research.
🧵We are pleased to announce that the UMCG - Universitair Medisch Centrum Groningen in the Netherlands is now officially accredited as a trial site for the STOP-PKD Study.
🧵 1/4 Living with #ADPKD? Take the survey and use your voice to shape the future of ADPKD research. 📣 survey.uni-koeln.de/index.php/31... 🪡 Read this thread 👇 #PKD #PatientVoice #OpenScience #RareDisease #KidneyHealth #HorizonEurope #European #Research
My first rare disease day at University Hospital Düsseldorf. Great to see this is an active topic on site. Looking forward to setting up the Center for Rare and Genetic Kidney Diseases and continuing the efforts to improve patient care and research in this area. @hhu.de
🚀 STOP-PKD-News! Das zweite Prüfzentrum in Mainz ist nun offiziell freigegeben. Weitere folgen (DE, NL, ES, AT). Kann SGLT2-Inhibition das Fortschreiten von Zystennieren positiv beeinflussen? Infos und Kontakte: stop-pkd.de #STOPPKD #ADPKD @pkdinternational.bsky.social @pkdgermany.bsky.social
Looking forward to continuing the collaboration with @pkdinternational.bsky.social in this new position.
PKD International @pkdinternational.bsky.social · 5mo agoPKD International warmly congratulates @muellerrom.bsky.social on this important new step. We are deeply grateful for his unwavering commitment to patient advocacy and for his continuous efforts to advance the interests of the PKD community.
👩🔬 Today is International Day of Women and Girls in Science! Meet Malvika Ramani, PhD student in the group of @muellerrom.bsky.social at the @unicologne.bsky.social
