Muriel Perron
@murielperron.bsky.social
CNRS researcher interested in neural stem cells, retina, and regeneration
#ResultatScientifique🔎| Pourquoi les neurones sont-ils tous différents ? Des scientifiques dévoilent les mécanismes à l'origine de leur identité 🧠 ▶️ buff.ly/l676Amf ✍️ Félix Simon/Claude Desplan 📕 @NatureNeuro 🤝 @cnrs.fr @ijmonod.bsky.social @upcite.bsky.social @cnrs-idf-villejuif.bsky.social
Aux origines de l’identité des neurones
Comment le cer
buff.ly
🔬 Diverse species. Stem cells. Highly international team. 🐸🐭 We’re looking for a Technical Assistant to join our stem cell–based research. Interested? Apply here 👉 jobs.tue.mpg.de/jobs/276
Online Application System - Max Planck Campus Tübingen
jobs.tue.mpg.de
🦈 Idoia Quintana Urzainqui is launching her new Neuroshark group in at NeuroPSI with the support of @erc.europa.eu. She is now hiring a lab manager and a Bioinformatics post-doc. ➡️ Learn more and apply: Post-Doc: euraxess.ec.europa.eu/jobs/428992 Lab Manager: euraxess.ec.europa.eu/jobs/429039
🦈🧠2 JOB OFFERS in the brand-new Neuroshark group starting at the Institute of Neuroscience Paris-Saclay (NeuroPSI)? Lab manager: www.linkedin.com/posts/idoia-... Bioinformatician: www.linkedin.com/posts/idoia-... Curious about the lab but not your profile? Feel free to contact me
Lab manager job | Idoia Quintana Urzainqui
JOB OPPORTUNITY 🦈 🧠 🔬. We are looking for a Lab Manager to help establish a new group studying shark embryos to understand the origin of the vertebrate brain. Reach out if this motivates you. We’re ba...
linkedin.com
#SdC2026 Retrouvez Carole Escartin, cheffe d'équipe à NeuroPSI, dans une table ronde et plusieurs reportages de @glialclub.bsky.social sur le rôle des cellules gliales dans la maladie d’Alzheimer, dans a cadre de la semaine du cerveau ! 🔽🔽🔽
French Glial Cell Club@glialclub.bsky.social · 5mo agoPour la Semaine du Cerveau #SdC2026 le Club des Cellules Gliales et France #Alzheimer ont concocté pour vous une immersion dans trois laboratoires et une table ronde pour vous plonger au cœur de la recherche et mieux comprendre le rôle des cellules gliales. Replay : www.youtube.com/watch?v=5v5z...
European Amphibian Conference 2026, July 3-5, 2026, Prague, Czech Republic www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
🐸 Amphibians take over Europe!! 📍 Prague. July 3–5, 2026. The European Amphibian Conference 2026 is coming: 3 days of cutting-edge science, bold ideas, iconic speakers, and serious frog & axolotl energy ✨ 👉 Register. Submit. Be there. Do not miss it. amphib-conf2026.sciencesconf.org?lang=en
Happy to announce that our latest paper is now out! Have you ever wondered how neural tissues control their size? In this paper, we show that cell division orientation is critical in both the cortex and retina. www.science.org/doi/10.1126/...
Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species
A fundamental role for division orientation in progenitor output driving cortical and retinal growth is revealed.
science.org
➡️ This study is complemented by a compagnon study focused on the conservation of Mexican tetra blind cave fish 🔽🔽🔽
Long-term genetic mark and recapture in Astyanax mexicanus cave populations: demographic inferences and conservation issues - Conservation Genetics
The cave populations of Astyanax mexicanus in northeastern Mexico are the subject of intensive study as a model for investigating evolutionary processes in subterranean environments. Investigating key...
doi.org
➡️ In a new Ecology and Evolution paper, Sylvie Rétaux's team @neuropsi.bsky.social and collaborators report on more than 15 years of field studies on the water physicochemical parameters and hydrodynamic regimes in the Mexican tetra blind cave fish habitat 🐟💦. ➡️ Learn more 🔽🔽🔽
Water Parameters and Hydrodynamics in Rivers and Caves Hosting Astyanax mexicanus Populations Reveal Macro‐, Meso‐ and Microhabitat Characteristics
From 2009 to 2025, we have recorded the physicochemical parameters of the water and the hydrological regimes at localities hosting Astyanax mexicanus cavefish and surface fish populations in Mexico. ...
onlinelibrary.wiley.com
🧠 👩🎓 University Paris-Saclay launches its all-new Master in Neuroscience! One M1 in neuroscience, followed by three M2: 1️⃣ Cognition, Behavior and Mental disorders. 2️⃣ Systems Neuroscience: from cells to brain functions. 3️⃣ Computational Neurosciences and Neuroengineering. 🔽🔽 Learn more & apply:
Saclay_master_in_neuroscience
sDrive
sdrive.cnrs.fr
🦾/💪 Interested in the physiology of motor control? In robotics? In neuroprosthetics? ▶️ Join us in NeuroPSI for NeuroControl 2026, the conference on the physiology and engineering of limb and prosthesis closed-loop control! ▶️ Register and submit your abstract: neurocontrol.sciencesconf.org
👏 Upcoming seminars at NeuroPSI in January (11:30am): ➡️ The 23rd, Marc Dhenain, Institut de Biologie François Jacob, "Pseudo-prions to treat neurodegenerative diseases." Followed by two speakers on motor control: ➡️ The 27th, Maarten Zwart, from St Andrews. ➡️ The 30th, Graziana Gatto, from Cologne.
🎖️Toutes nos félicitations à Sylvie Rétaux, cheffe de l'équipe DECA à NeuroPSI, qui a été nommée au grade de Chevalier de la Légion d’Honneur !
Second paper is a collaboration with Jim Handa's lab at Hopkins. Cigarette smoke exposure induces aging-related molecular changes in both mouse and human retinal pigment epithelium. www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
The lab's first paper of the new year is out. In it, we investigate the role of the late stage retinal progenitor-enriched SoxE family factors Sox8 and Sox9 in controlling retinal development./1 www.biorxiv.org/content/10.6...
Sox8 and Sox9 regulate differentiation and nuclear positioning of retinal Müller glia
Temporal patterning of retinal progenitor cells governs the sequential generation of retinal cell types, with gliogenesis occurring late in development. Sox8 and Sox9, members of the SoxE transcription factor family, are highly expressed in late-stage retinal progenitor cells and mature Müller glia, yet their functional roles remain incompletely defined. Here we employed gain- and loss-of-function approaches, single-cell multiomic profiling, and injury models to investigate Sox8/9 function. Overexpression of SOX8 and/or SOX9 in early-stage retinal progenitor cells suppressed early-born cell fates and promoted photoreceptor generation, consistent with a role in late-stage temporal identity. Conversely, conditional deletion of Sox8 and/or Sox9 in late-stage progenitors did not impair Müller glia specification, but caused radial displacement of Müller glia nuclei into the outer retina and modest changes in glial gene expression. Loss of Sox8/9 in mature Müller glia modestly increased proliferation post-injury without inducing neurogenic competence. These findings suggest that Sox8/9 are dispensable for gliogenesis and repression of neurogenic competence, but are essential for proper laminar positioning and maturation of retinal Müller glia. ### Competing Interest Statement S.B. is a cofounder, shareholder, and scientific advisory board member of CDI Labs LLC, and receives research support from Genentech. National Eye Institute, https://ror.org/03wkg3b53, R01EY036173
biorxiv.org
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
bioRxivpreprint@biorxivpreprint.bsky.social · 7mo agoEvolutionary dynamics of temporal transcription factor series in the insect optic lobe https://www.biorxiv.org/content/10.64898/2026.01.08.698497v1
..and on the 9th, at 11:30am, we will hear Ariel Levine, from NIH Bethesda, talk about "Building the Spinal Cord". Join us for these two talks at @neuropsi.bsky.social !
📅 NeuroPSI Seminar Series. On the 8th of January at 10:30am, we will be hosting Colline Poirier, Biosciences Institute of Newcastle University. ▶️ She will talk about: "Using spontaneous behaviour to assess primate welfare"
Join the development of the mouse forelimb prosthesis as a post-doc, apply!
Luc Estebanez@lucestebanez.bsky.social · 7mo ago🦾 🧠 Are you interested in building and experimenting with the second version of our mouse forelimb prosthesis? Apply to our Post-Doc position at Université paris-Saclay. Neuroscientists with interest for engineering, and engineers with interest for neurosciences all welcome! Apply now 🔽🔽🔽
Really happy to join NeuroPSI at Paris Saclay to lead a research group funded by an ERC Consolidator grant #ERCCoG . We'll study the origins of the vertebrate brain using shark embryos. 🦈 🧠 Reach out if you are interested in joining the team 🤍
Paris-Saclay Institute of Neuroscience@neuropsi.bsky.social · 8mo ago🙋♀️ We are welcoming Idoia Quintana Urzainqui to NeuroPSi as a junior Professor! In her new team, she will research the Mechanisms that shaped early vertebrate brains, thanks to funding from a 2025 ERC Consolidator grant. ➡️ Learn more here: neuropsi.cnrs.fr/en/idoia-qui...
Sylvie Granon, chercheuse à NeuroPSI, a participé à une émission de SynapseTV, la première webTV dédiée à la santé mentale, autours de la thématique des écrans et de leur impact sur le cerveau: www.youtube.com/watch?v=d1v9...
Congratulations to our NeuroPSI team leader Carole Escartin for the 2025 Prize Marie-Paule Burrus from @frm-officiel.bsky.social !
💎 Valérie Lavallée, responsable de la plateforme de zootechnie de l’Institut des Neurosciences Paris-Saclay, a obtenu la Médaille de cristal du CNRS 2025: une récompense pour son parcours et sa contribution essentielle à la recherche dans notre institut !
Valérie Lavallée
Grâce à son parcours autodidacte remarquable, Valérie Lavallée a connu une progression de carrière constante jusqu’à être nommée responsable de la plateforme de zootechnie de l’Institut des Neurosciences Paris-Saclay (NeuroPSI - CNRS/Université Paris-Saclay), situé sur le campus du CEA Saclay. En 2021, elle a notamment relevé le défi de l’installation d’une plateforme de zootechnie multi-espèces lors du déménagement du laboratoire. En 2025, le CNRS décernera la médaille de cristal à Valérie Lavallée pour la qualité de son travail et pour son rôle majeur dans ce déménagement, qui a permis le regroupement des sites zootechniques de Gif-sur-Yvette et Orsay vers le nouveau bâtiment de NeuroPSI. Cette plateforme est désormais une vitrine de l’excellence en zootechnie scientifique.
iledefrance-gif.cnrs.fr
🙋♀️ Welcome to Marion Rivalan, who joins NeuroPSI as a CNRS Junior Professor! ➡️ Her project will leverage AI-based methods for the classification and prediction of individual profiles of model animals housed in a naturalistic environment. ➡️ Learn more: neuropsi.cnrs.fr/en/marion-ri...
🙋♀️ We are welcoming Idoia Quintana Urzainqui to NeuroPSi as a junior Professor! In her new team, she will research the Mechanisms that shaped early vertebrate brains, thanks to funding from a 2025 ERC Consolidator grant. ➡️ Learn more here: neuropsi.cnrs.fr/en/idoia-qui...
A bit late but a paper from our lab has been published! Human fingertip regeneration is a fact, it happens in children and adults (not only in children as it has been long believed). We describe here the regenerative phases and analyse the proteome of wound exudates. www.nature.com/articles/s41...
🚨We are recruiting two PhD students 🚨 1) Quantitative & dynamic analysis of limb-regenerative signaling centers w/ @osvaldo-chara.bsky.social 📶🧮💻 🔗https://www.phd.tuebingen.mpg.de/80704/Quantitative-and-dynamic-analysis-of-limb-regenerative-signaling-center-interactions
Recent Hopkins Hub article highlighting our work on optic nerve regeneration in axolotl. Congratulations to Ted! hub.jhu.edu/2025/12/11/s...
Could axolotls hold the key to restoring human vision?
Axolotls can regenerate optic nerves, retinas, and parts of their brain. Provost's Undergraduate Research Award-winner Ted Chor wants to understand how.
hub.jhu.edu
