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Mary Weber (Weber lab)

@mweberlab.bsky.social

Associate Professor at the University of Iowa. Studying host-pathogen interactions, with a focus on Chlamydia and Orientia effector proteins and host cell biology.

50 Posts449 Follower142 Folgt
Mary Weber (Weber lab)@mweberlab.bsky.social · 3mo ago

Excited to share our new paper in mBio! We show that the Chlamydia trachomatis effector protein CT181 binds Mcl-1, prolongs neutrophil survival, enhances bacterial persistence, and promotes infection/pathogenesis in vivo.

Mary Weber (Weber lab)@mweberlab.bsky.social · 3mo ago

We’re hiring in the Weber Lab at the University of Iowa! We study how intracellular pathogens (Chlamydia trachomatis and Orientia tsutsugamushi) manipulate host cells through secreted effector proteins. Two great opportunities for future scientists and research professionals.

Sarah Hird, PhD@sarahhird.bsky.social · last yr.

PSA for NIH R35s: My R35 was administratively withdrawn this year because I broke my Future Research into “Aims” & they said this violated the “Do not submit a Specific Aims page or identify specific aims” policy. So. Don’t use the word “Aims” in an R35 - use “Projects”. #critical

Screenshot of email from NIH PO that reads: “Unfortunately, they have become very strict this round with the use of the word Aims (even if the PIs meant program projects) to describe discrete projects in their research strategy. This was decided at the Director level. There were a few other PIs that were I the same boat and all the applications were withdrawn.”
Mary Weber (Weber lab)@mweberlab.bsky.social · 2y ago

Stunning microscopy and fascinating new insights from @lamasonlab.bsky.social on Rickettsia-ER contact sites. Incredible work!

Journal of Cell Biology@jcb.org · 2y ago

Yamilex Acevedo-Sánchez et al. @lamasonlab.bsky.social characterize a novel interkingdom contact site between the ER and a cytosolic bacterial pathogen. They report that these bacteria–ER contacts (BERCs) require the tethering proteins VAPA and VAPB. https://buff.ly/4gXzZfI

Mary Weber (Weber lab)@mweberlab.bsky.social · 2y ago

🎉 Big congratulations to MSTP student Xavier Tijerina and Postdoctoral Fellow Jabeena on the release of their exciting preprint! 🚀 Their work sheds new light on CpoS and its interactions with host and other Inc proteins! Check it out here: www.biorxiv.org/content/10.1...

Tetramer formation of CpoS facilitates Inc-Inc interactions during Chlamydia trachomatis infection

Chlamydia trachomatis ( C.t. ), the leading bacterial cause of sexually transmitted infections, replicates within a unique intracellular compartment called the inclusion, which is modified by secreted...

biorxiv.org