Michael Galperin

@mygalperin.bsky.social

Lead Scientist at the Division of Intramural Research (formerly NCBI), NLM, NIH. Bacterial signaling, c-di-GMP, c-di-AMP, protein domains, COG database

We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures. Join our speakers & register today! ➡️https://bit.ly/47rtkbw #ProkaryoticCellBio

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Everyone interested in bacterial signal transduction, environmental sensing and motility, don't miss this conference organised by Ariane Briegel @arianebriegel.bsky.social and myself! We have great invited speakers and a number of slots allocated to short talks: www.grc.org/sensory-tran...

2026 Sensory Transduction in Microorganisms Conference GRC

The 2026 Gordon Research Conference on Sensory Transduction in Microorganisms will be held in Ventura, California. Apply today to reserve your spot.

grc.org

New paper alert! We used our fav technique, genetic suppression, to understand how FimX controls function of the T4P PilB motor ATPase in Pseudomonas aeruginosa. Great collab with the Ellison lab at U Georgia who helped with some fancy microscopy to capture pilus dynamics! doi.org/10.1371/jour...

Twitching motility suppressors reveal a role for FimX in type IV pilus extension dynamics

Author summary Type IV pili enable Pseudomonas aeruginosa to attach to surfaces, move (twitch), and form biofilms. Pilus extension is powered by the motor protein PilB, which is regulated by other fac...

doi.org

Viral AlphaFold Database (VAD) is live in Science Advances ~27,000 predicted viral protein monomers & homodimers Conserved folds across bacteria, archaea & eukaryotic viruses New toxin–antitoxin system KreTA uncovered Vast “functional darkness” remains uncharted www.science.org/doi/10.1126/...

The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes

VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.

science.org

Thrilled to be a coauthor in this story 🚀 Check out our latest publication on the archaellum - spoiler: it's an archaellum in bacteria 😱 Who would have thought? Thank you to all the authors, and especially @sshamphavi.bsky.social for really keeping this paper rotating 😉

Sonja-Verena Albers@archaellum.bsky.social · 12mo ago

Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com www.nature.com/articles/s41... Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social