This is very cool work! Most research in statistical genetics does not take evolutionary theory into account, but Hanbin's paper shows how doing so can explain the success of empirically-derived models and make them even more effective.

Hanbin Lee@epigenci.bsky.social · 3w ago

How should we apply linear mixed models to populations under stabilizing selection? The first paper I wrote with my grad school advisor is published in Genetics. academic.oup.com/genetics/adv... 1/n

I'm excited to share that I have been awarded a postdoctoral fellowship from the @stanford.edu Center for Computational, Evolutionary and Human Genomics (CEHG)! stanfordcehg.wordpress.com/2026/05/29/a...

Announcing the 2026-27 CEHG Fellows

CEHG received a stunning amount of qualified applicants to this year’s fellowship cycle! We will be supporting six PhD students and three postdoctoral scholars across various disciplines this…

stanfordcehg.wordpress.com

"mtDNA copy number and expression are largely decoupled, and above a certain rate-limiting threshold, mtDNA accessibility — rather than absolute copy number — is the more relevant quantity for explaining inter-individual differences in gene expression."

Arslan Zaidi@aazaidi.bsky.social · 2mo ago

Our preprint on the genetic regulation of mtDNA gene expression in collaboration with @shwetaramdas.bsky.social and @rajivmccoy.bsky.social .

IGES is my favorite scientific conference. It has a small, intimate feel and remains focused on genetic epidemiology and statistical genetics, which makes networking easy and puts your research in front of an enthusiastic audience. I'm going again and hope to see many of you there!

International Genetic Epidemiology Society@geneticepi.bsky.social · 2mo ago

Why submit an abstract to #IGES2026? • Contribute to leadership, innovation, and excellence in research. • Elevate awareness of your work and its impact. • Expand your professional network and connect with global experts in genetic epidemiology. Submit your best work now ➡️ www.geneticepi.org

After closely following generative AI research for the past several years but intentionally not using AI in my own work, I finally decided to bite the bullet. So far, it is both more useful and less useful than I expected.

"What matters is the process: the development and application of methods, the training of minds, the creation of people who know how to think about hard problems. If you hand that process to a machine, you haven't accelerated science. You've removed the only part of it that anyone actually needed."

Minas Karamanis@minaskar.bsky.social · 4mo ago

Hey, I wrote a thing about AI in astrophysics ergosphere.blog/posts/the-ma...

It's so exciting to see the company where I interned as a PhD student obtain their first FDA approval! This is huge news for the Hunter Syndrome community and a major milestone in the development of biotherapeutics that cross the blood-brain barrier. investors.denalitherapeutics.com/news-release...

I'm proud to see that my PI @lindakachuri.bsky.social has been elected to the @geneticepi.bsky.social Board of Directors! It's time to make IGES cool again 😎

International Genetic Epidemiology Society@geneticepi.bsky.social · 5mo ago

Congratulations to the winners of this year's IGES leadership elections! 🎉🎉🎉 • President Elect: Elizabeth Blue • Treasurer: Cheryl Cropp • Board of Directors: @lindakachuri.bsky.social and @burcudarst.bsky.social

I wanted to keep this account focused on science, but it is hard to stay silent on political issues right now. My home country is still being bombed by Russia, the city I lived in for the past several years is under occupation by ICE, and the funding that supports my work is constantly threatened.

My second dissertation paper is now out in @natcomms.nature.com! Here we introduce the co-expression-wide association study (COWAS) method for identifying pairs of genes or proteins whose genetically regulated co-expression is associated with complex traits. 🧵⬇️ www.nature.com/articles/s41...

Co-expression-wide association studies link genetically regulated interactions with complex traits - Nature Communications

Proteins can affect traits through their interactions with one another. Here, the authors propose the COWAS method to identify pairs of interacting genes or proteins whose genetically regulated co-exp...

nature.com

"The aim of equity is not to brag about how many students of a target background you awarded an A in calculus, it’s to ensure that every student actually learns." This is such an important and timely article. I have noticed a lot of the same issues myself. www.theargumentmag.com/p/when-grade...

When grades stop meaning anything

The UC San Diego math scandal is a warning

theargumentmag.com

This is an exceedingly late post, but I wanted to share a few pictures from #IGES2025 earlier this fall. I had the honor of giving a platform talk on age-related genetic dysregulation, and I really enjoyed connecting with other researchers and exploring the beautiful city of Cologne!

We can't wait to see you in Cologne this week for #IGES2025!! See below for some important reminders 👇

The use of dichotomized labels for traits that are actually continuous has bothered me ever since I started working on complex trait genetics. Sasha's blog post provides an excellent explanation of why this matters in the context of polygenic risk and embryo selection.

Sasha Gusev@sashagusevposts.bsky.social · 12mo ago

I wrote about how genetic risk works in the context of embryo selection and how people often think about it all wrong. A short 🧵:

Yesterday I successfully defended my dissertation! It feels surreal to finally reach the end of my PhD journey at @umnsph.bsky.social. Thank you to my adviser Wei Pan and to my committee members @elock.bsky.social, @aazaidi.bsky.social, and Thierry Chekouo for your invaluable mentorship and support!

I had a great time at STATGEN 2025 last week! Thank you to everyone who came to my talk and to the organizers for putting on this conference.

This year's IGES Annual Meeting and Education Workshop will be held Aug. 31 - Sept. 2 in the beautiful city of Cologne, Germany. Join us for an exciting lineup of keynote presentations, platform talks, posters, and hands-on tutorials at #IGES2025! Learn more: www.geneticepi.org/2025-annual-...

Follow @geneticepi.bsky.social to stay up to date on news and events from IGES! This will be the society's primary social media presence going forward, and we will be sharing a lot of cool and useful content. Full disclosure: I manage the IGES account.

International Genetic Epidemiology Society@geneticepi.bsky.social · last yr.

The International Genetic Epidemiology Society (IGES) is now on Bluesky! 👋🧬 We are the only international scientific society devoted to promoting the study of genetic epidemiology and statistical genetics. Follow along for the latest from IGES! #genetics #epidemiology #statistics #science #IGES

A reviewer described my COWAS method as "a significant breakthrough in the study of gene-gene (protein-protein) interaction." Before that, the very same paper was desk rejected by four other journals. The moral of this story is obvious and left as an exercise to the reader.

I'm excited to share our latest work, now out in #PLOSGenetics! If you feel limited by linear models in TWAS or PWAS but don't think you can switch to nonlinear methods due to a lack of individual-level phenotype data, this paper is for you. 🔗 journals.plos.org/plosgenetics... Thread below 👇 (1/6)