💥 We made the COVER 🤩 of @natmater.nature.com ! CELL VISCOSITY 🎈 IN METASTATIC EXTRAVASATION Check the entire issue here : lnkd.in/e9USS44n @inserm.fr @unistra.fr #zebrafish #mouse #metastasis #mechanobiology #imaging #materials Note : Image's credit is V.Gensbittel (PAA bead in a ZF ISV)

💥 First time getting one of my paper highlighted. Truly honored coming from someone whose seminal work has been inspiring when I entered the field of cancer mechanobiology. Thanks to Konstantinos Konstantopoulos and colleagues for the highlight in @aacrjournals.bsky.social Cancer Research🙏.

Jacky Goetz@goetzjacky.bsky.social · 7mo ago

Not just soft 🎈 Many thanks to the team of K.Konstantopoulous #JohnsHopkins for throughly discussing our recently-published story in @aacrjournals.bsky.social #CancerResearch Highly appreciated 🙏 Link : aacrjournals.org/cancerres/ar... Our original paper : www.nature.com/articles/s41...

Postdocs wanted - Please spread the word! We are looking for one bioinformatician and 1-2 cell biologists with different expertise! See the job ad below for more information and links to the job descriptions!

💡 Have you ever wondered how #circulating #tumor cells squeeze through narrow #capillaries during hashtag#metastasis ? 💥 We did, check out our latest publication just out #NatureMaterials: rdcu.be/eZHxJ

💥finally here💥. Our latest manuscript (@goetzjacky.bsky.social lab) is out in @natmater.nature.com. We show that cell viscosity drives the metastatic potential. A project handled by former PhD student Valentin Gensbittel, help from Zeynep Yesilata & many labmates! www.nature.com/articles/s41...

Cell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells - Nature Materials

The viscosity of tumour cells is shown to govern their ability to disseminate through the bloodstream and extravasate, establishing a key biomechanical factor of metastasis.

nature.com

Naël Osmani@naelosmani.bsky.social · last yr.

🎉Beyond happiness... this was a long story ! Well handled by our former PhD student Valentin Gensbittel. Initiated back when I was a post doc and now finalized as a tenured researcher in @goetzjacky.bsky.social lab ! If you can't wait the initial version is still here www.biorxiv.org/content/10.1...

Ysterday was quite an amazing day for me and the TBL lab @goetzjacky.bsky.social . Amandine Dupas (my first PhD student) brilliantly defended her PhD with an excellent presentation and an outstanding scientific discussion ! I could not be more proud. Congratulations Amandine this is well deserved 👏

It has been a privilege to assist to the Ruban Rose award ceremony with Research Grand Prize awarded to @goetzjacky.bsky.social at the Hôtel de Lassay. Thanks for this amazing time and always sharing the light with your team 🙏. We are very grateful to the Association Ruban Rose for their support.

📢Internships on cellular nematics! 🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis. 📧Feel free to DM or email me with any questions.

Very happy to share the beautiful cover of @cp-trendscancer.bsky.social that is designed based on our review article on #platelets and their role, usage and targeting in #cancer and its #therapy Link to the full issue : www.cell.com/issue/S2405-... @inserm.fr @unistra.fr

Just back from an awesome #zebrafish meeting in #Toulouse. Vibrant and caring French community around one of our favorite model system 🐠🦓 With Zeynep YESILATA Laurie Nemoz-Billet & Naël OSMANI, we presented some of our current work using that model

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park! “Specialized gas-exchange endothelium of the zebrafish gill” — www.biorxiv.org/content/10.6... Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

[Job] Postdoctoral Researcher/PhD Student/Research Technician, Hoijman Lab, IBMB-CSIC, Barcelona, Spain #zebrafish

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions: Mentoring Profile raising Leadership training Network building Spread the word... www.biologists.com/grants/devel...

Development's Pathway to Independence Programme

Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...

biologists.com

is there a direct crosstalk between actin and vimentin intermediate filaments? Our work shows that vimentin promotes actin assembly by stabilizing ATP-subunits at the barbed end. Fantastic work done by @lilianpaty.bsky.social with @romet-jegou-lab.bsky.social www.biorxiv.org/content/10.1...

It’s official! 🎉 Our latest paper on the role of the extracellular matrix (ECM) in megakaryopoiesis is out in @elife.bsky.social ! 🔗 elifesciences.org/articles/104... I’m thrilled to share this story with you in a short thread 👇

Check out the final version of this insightful work by Claire Masson and our long-lasting collaborators #EFS #UMR1255. Very glad to be part of it with @naelosmani.bsky.social and kudos to @elife.bsky.social for a very transparent publishing process. doi.org/10.7554/eLif...

🎉Beyond happiness... this was a long story ! Well handled by our former PhD student Valentin Gensbittel. Initiated back when I was a post doc and now finalized as a tenured researcher in @goetzjacky.bsky.social lab ! If you can't wait the initial version is still here www.biorxiv.org/content/10.1...

Cell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells

Metastases arise from a multi-step process during which tumor cells change their mechanics in response to microenvironmental cues. While such mechanical adaptability could influence metastatic success...

biorxiv.org

Jacky Goetz@goetzjacky.bsky.social · last yr.

💥 Paper accepted (in principle) #cellfie 🤩 A long wait, a beautiful project, some amazing collaborations. Stay tuned for more ! ALT : how cells (and cell-like beads) are deformed in constraining vessels

Exciting times in the lab 🤩 Today, we have received the first #deformability #cytometer in France 🇫🇷 We will be measuring #mechanics of many cell types and conditions 🧫, and coming from various samples ⚙️ Thanks Rivercyte & Martin Kräter for the training and delivery (and for the beer 🍺)

#JobOffer 💼 Post doc to study the impact of mechanics on skin cell differentiation (M/F) 📅 October 1st 📍 Institut Jacques Monod / @bladoux.bsky.social / @rmmege.bsky.social Lab Apply on the CNRS job portal before July 22nd🔗 emploi.cnrs.fr/Offres/CDD/U...

Thank you @dna, our local newspaper, for spreading our efforts in better understanding #metastatic progression of #cancer. www.dna.fr/sante/2025/0...

Sciences. Des chercheurs de Strasbourg identifient une nouvelle piste pour lutter contre la formation des métastases

En s’attelant à décrypter les mécanismes qui permettent aux cellules cancéreuses de traverser la paroi des vaisseaux sanguins, une équipe de ...

dna.fr

Check this out : wizardry, I told you !

Katerina Jerabkova-Roda@katkajerabkova.bsky.social · last yr.

Fast and efficient lysosome clustering in patient-derived metastatic melanoma cells (Black= LAMP1, Magenta= LifeActin). Spinning disk imaging @PIC-STRA. #fluorescencefriday #livecellimaging #lysosomes Read more here: rdcu.be/eg6k3

(1/6) Preprint alert : check out our latest work with regards to the contribution of #platelets to #metastasis. 👉 @biorxivpreprint.bsky.social : lnkd.in/d5cv4eeA This has been driven by Vincent Mittelheisser & Cristina Liboni in my lab, in collaboration with @inserm.fr 1255 (P.Mangin).

💥 New study : check out @katkajerabkova.bsky.social Katka's wizardry in the lab 🧙‍♂️ Building on the #Nanotumor consortium that we launched few years back, we now provide solid evidence that melanoma cells' inner architecture controls the progression of #melanoma to #metastasis rdcu.be/eg8EU (1/3)

Peripheral positioning of lysosomes supports melanoma aggressiveness

Nature Communications - The function and position of organelles are pivotal for tumor cell dissemination. Here the authors use melanoma patient samples and animal models to show that peripheral...

rdcu.be

The latest co-authored #preprint @biorxivpreprint.bsky.social is out. First foray into renal carcinoma, work driven by Beatrice Cesana under the guidance of Odile Filhol (& Claude Cochet). Experiments and supervision by Laurie Nemoz-Billet & Naël OSMANI in the lab www.biorxiv.org/content/10.1...

Mind blowing imaging 🤩 showing how amazing of a model zebrafish is ! Congrats to all authors !

Dan 🐟 C@zebrafish007.bsky.social · 2y ago

Excited to see our work describing an external immune organ in the #zebrafish published in JEM! Big thanks to Aurora Kraus and @zebrafishmk.bsky.social and all of our other amazing collaborators including @edanfoley.bsky.social @biomarina-vg.bsky.social #WeinsteinLab rupress.org/jem/article-... 🧪

Thank you @inserm.fr for highlighting again our work on the very important role of the #vascular wall in #metastasis ! Great job by a group of people lead by @naelosmani.bsky.social in our lab. www.inserm.fr/actualite/ca...

Cancer : une nouvelle piste pour lutter contre la formation des métastases · Inserm, La science pour la santé

En s’attelant à décrypter les mécanismes moléculaires qui permettent aux cellules cancéreuses de traverser la paroi des vaisseaux sanguins, une équipe strasbourgeoise vient d’identifier une nouvelle p...

inserm.fr

Go and see Cristina at poster #147 - she is awesome 🤩

Jacky Goetz@goetzjacky.bsky.social · 2y ago

How could one resist to come to their talks 🤩 ! #morningenergy #earlybirds #CRCLsymposium

How could one resist to come to their talks 🤩 ! #morningenergy #earlybirds #CRCLsymposium

Jacky Goetz@goetzjacky.bsky.social · 2y ago

Part of the lab made it to the fantastic CRCL 6th international Cancer Symposium 🥰 Don’t miss our talks tomorrow if you are there : @katkajerabkova.bsky.social in the metastasis & invasion session at 9.45am and Cristina with a poster (and a teaser around noon)

Part of the lab made it to the fantastic CRCL 6th international Cancer Symposium 🥰 Don’t miss our talks tomorrow if you are there : @katkajerabkova.bsky.social in the metastasis & invasion session at 9.45am and Cristina with a poster (and a teaser around noon)

🎄 Our last 2024 study is out 🤩 Check it out @isciences.bsky.social @cellpress.bsky.social doi.org/10.1016/j.is... A masterpiece driven by Marina, consolidated by Amandine and spearheaded by @naelosmani.bsky.social in the lab. What have we found ?

Jacky Goetz@goetzjacky.bsky.social · 2y ago

#paperalmostaccepted movie ! Stay tuned ! Legend : Endothelial calcium signaling during metastatic extravasation 🤩 #christmas #firing