Come join the @socialfluids.bsky.social lab in Cambridge to study the evolution of Socially Transferred Materials! Fun new HFSP project btwn UK, NL and Costa Rica! Deadline September 7th #Postdoc #JobAlert #Evolution #Bioinformatics #STM #socialfluids www.cam.ac.uk/jobs/researc... leboeuflab.com

If you missed out, you're in luck 🍀. We have extended abstract submissions to EPIDIDYMIS IX for another week! Submissions closing 5pm (CET) JULY 10. Final chance to join our incredible line up of invited speakers! www.esa-srb-nzse.org/epididymal-w...

One more week to submit an abstract for Epididymis 9! www.esa-srb-nzse.org/epididymal-w...

www.yahoo.com/news/article...

Do you take after your dad’s RNA?

Evidence is growing from rodent studies that sperm carries marks of a father’s life experiences, influencing traits in offspring. Bits of RNA could be the drivers of these epigenetic effects.

yahoo.com

And highlighted in Science! www.science.org/content/arti...

Sperm carry unexpected genetic messages

Maturing mouse sperm get loaded with full-length messenger RNAs that are transferred to fertilized egg, suggesting a new route for paternal influence

science.org

Nat Trigg@natrigg.bsky.social · 4mo ago

Now published in NAR - doi.org/10.1093/nar/... Huge thanks to @colinconine.bsky.social and co-authors @alexisgleach.bsky.social @gracelee.bsky.social Check out our accompanying web app to explore the data too. reprodatahub.shinyapps.io/Epididymal_m...

Now published in NAR - doi.org/10.1093/nar/... Huge thanks to @colinconine.bsky.social and co-authors @alexisgleach.bsky.social @gracelee.bsky.social Check out our accompanying web app to explore the data too. reprodatahub.shinyapps.io/Epididymal_m...

Colin Conine@colinconine.bsky.social · 12mo ago

New from the lab led by @natrigg.bsky.social. We started by characterizing mRNA in sperm, EVs, and the epithelium across epididymal transit. This revealed evidence that sperm acquire specific mRNAs through fusion with epididymal EVs, which we further established with in vitro co-incubation assays

Epididymal extracellular vesicles harbor and convey mRNA to sperm for transfer to zygotes academic.oup.com/nar/article/...

We are recruiting a PhD student! A fully-funded position at The University of Newcastle, Australia. The candidate will be part of a team investigating how the sperm RNA profile is shaped. See more in link below or get in touch.

Male mice exposed to PFAS (an environmental contaminant) have reduced sperm production but normal sperm viability & motility. Embryos created by IVF with PFAS-treated sperm have disrupted transcriptomes suggesting possible transgenerational effects. www.nature.com/articles/s42...

Exposure of mice to environmentally relevant per- and polyfluoroalkyl substances (PFAS) alters the sperm epigenome - Communications Biology

Male mice exposed to PFAS (a group of environmental contaminants) have reduced sperm production but normal sperm viability & motility. Embryos created by in vitro fertilisation (IVF) with PFA...

nature.com

Check out our (@natrigg.bsky.social and Grace Lee) protocol for determining the functions of sperm, and other, RNAs during early development. star-protocols.cell.com/protocols/4200

Cell Press: STAR Protocols

STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...

star-protocols.cell.com

🚨 New Resource for Reproductive Researchers! 🧪🔬 Are you exploring sperm biology, male infertility, or contraceptive development? 📢 We’ve just released a comprehensive step-by-step guide (preprint) to generate and analyse human sperm phosphoproteomes; a crucial but underexplored area.

JCI Insight - In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects insight.jci.org/articles/vie...

Working with germ-free mice with the Kambayashi Lab we saw a 'swollen' epididymal phenotype occurring, so we took a closer look doi.org/10.1530/REP-...

A lack of commensal microbiota influences the male reproductive tract intergenerationally in mice

The microbiome encompasses the array of microorganisms inhabiting various niches in the body and is necessary for numerous physiological processes, including normal metabolism and a functioning immune...

doi.org

Australia is known for its hot conditions, but new findings from HMRI's Infertility and Reproduction research program have found that heatwave conditions can impact the health of sperm. Learn more hmri.org.au/news-and-sto...

Happy to have contributed to this led by the Nixon lab. We helped show temperarure can alter sperm small RNAs which modulate postfertiilzation embryonic gene expression and development in 🐁 www.pnas.org/doi/10.1073/...