Single-nephron eGFR and kidney function decline in IgA nephropathy

ABSTRACTBackground. During the progression of immunoglobulin A nephropathy (IgAN), residual nephrons compensate for nephron loss by increasing single-nephr

academic.oup.com

IgA nephropathy occurrence, treatment, and prognosis in the last two decades in Denmark

ABSTRACTBackground and hypothesis. IgA nephropathy (IgAN) is the leading cause of primary glomerulonephritis; however, reported incidences and prevalences

academic.oup.com

Efficacy and safety of finerenone in non-diabetic patients with IgA nephropathy

ABSTRACTBackground. Finerenone has been proven to have cardiovascular and renal protective effects on chronic kidney disease associated with type 2 diabete

academic.oup.com

Renal functional reserve predicts GFR response to empagliflozin in RENALIS and RACELINES clinical trials

ABSTRACTBackground. Glomerular hyperfiltration is common in type 2 diabetes (T2D) and may reflect reduced nephron number and/or perturbed intrarenal hemody

academic.oup.com

N-methyl-D-aspartate receptor inhibition protects against obesity-induced kidney disease

ABSTRACTBackground. Obesity-associated nephropathy is becoming increasingly prevalent, yet the molecular mechanisms linking metabolic stress to renal dysfu

academic.oup.com

Renal and urothelial cancer risks with SGLT2 inhibitors vs GLP-1 receptor agonists in type 2 diabetes: a target trial emulation

ABSTRACTBackground. The cardiovascular and renal benefits of sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonis

academic.oup.com

KDIGO 2026 Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD): a commentary from the European Renal Best Practice (ERBP)

ABSTRACT. The 2026 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Anemia in Chronic Kidney Disease represents a substant

academic.oup.com

Cardiovascular outcomes and acute kidney injury risk with combination therapies in type 2 diabetes and chronic kidney disease

To the Editor,

academic.oup.com

Dual anti-CD20/anti-CD38 therapy for severe recurrent FSGS with longitudinal anti-nephrin assessment

To the Editor,

academic.oup.com

Discordance between Mendelian randomization and randomized trials in nephrolithiasis: a multifactorial interpretation including pharmacogenetics

To the Editor,

academic.oup.com

Antiproteinuric effect of SGLT2 inhibitors in non-diabetic glomerulopathies is dependent on body mass index

ABSTRACTBackground. Sodium–glucose co-transporter 2 inhibitors (SGLT2is) are emerging as an essential part of the standard of care for proteinuria in patie

academic.oup.com

In situ assessment of glomerular C3/C5 convertases indicates ongoing complement activation in IgA nephropathy

ABSTRACTBackground and hypothesis. The complement system contributes to the progression of immunoglobulin A nephropathy (IgAN) and offers promising therape

academic.oup.com

Chronic kidney disease G3–5 in lupus nephritis—prevalence, progression, and risk factors

ABSTRACTBackground. Despite treatment advances, there are limited data on the development of chronic kidney disease (CKD) in patients with lupus nephritis

academic.oup.com

RNA interference medication and transplantation procedures in patients with primary hyperoxaluria type 1

ABSTRACTBackground and hypothesis. Defective hepatic alanine-glyoxylate aminotransferase (AGT) leads to oxalate overproduction in primary hyperoxaluria typ

academic.oup.com

Teneligliptin and empagliflozin attenuate ferroptosis-mediated acute tubular injury

ABSTRACTBackground. Ferroptosis is a key mechanism of tubular cell death in acute kidney injury (AKI), particularly in folic acid– and glycerol-induced mod

academic.oup.com

Urinary sediment predicts active proliferative glomerular diseases

ABSTRACTBackground. Several studies have demonstrated the utility of urinary sediment (U-sed) examination in patients with glomerular diseases (GDs).In thi

academic.oup.com

Steroid-sparing drugs in children and young adults with nephrotic syndrome: a target trial emulation

ABSTRACTBackground. Children and young adults with nephrotic syndrome are commonly treated with steroid-sparing immunosuppressive medications. Rituximab is

academic.oup.com

Efficacy and safety of telitacicept in adult IgA vasculitis nephropathy

ABSTRACTBackground. To investigate the efficacy and safety of telitacicept in adult immunoglobulin A vasculitis nephritis (IgAVN) patients with persistent

academic.oup.com

ERA’s ABCDE framework for kidney disease prevention: turning the WHO kidney health resolution into action

ABSTRACT. In 2025, the World Health Assembly of the World Health Organization (WHO) adopted a resolution on reducing the burden of noncommunicable diseases

academic.oup.com

Serum sodium levels and risk of all-cause mortality among hospitalized patients with chronic kidney disease

To the Editor,

academic.oup.com

Monoclonal gammopathy associates with kidney failure in ANCA-associated vasculitis

ABSTRACTBackground. Up to 20% of patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV) and kidney involvement progress to end-stage

academic.oup.com

The effect of GLP-1 receptor agonists on renal outcomes: a systematic review and meta-analysis

ABSTRACTBackground and hypothesis. Glucagon-like peptide-1 receptor agonists (GLP1-RAs) are anti-hyperglycaemic agents, with cardioprotective effects, howe

academic.oup.com

Prevalence of Strongyloides stercoralis in haemodialysis patients in Vienna

ABSTRACTBackground and hypothesis. Strongyloides stercoralis is a neglected parasitic infection endemic to tropical regions, with rising prevalence in Euro

academic.oup.com

Practice patterns and outcomes in cancer patients developing immune checkpoint inhibitors–related AKI

ABSTRACTBackground. Acute kidney injury (AKI) is a known immune-related adverse event of cancer immune checkpoint inhibitor (ICI) therapy. Further populati

academic.oup.com

Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI

ABSTRACT. Acute kidney injury (AKI) is a serious and common complication among patients undergoing major surgery. The underlying pathophysiologic mechanism

academic.oup.com

Diagnosis, diagnostic approach and challenges in pregnancy-associated AKI—the ADQI 32 consensus meeting

ABSTRACT. Despite advancements in obstetric care, pregnancy-associated acute kidney injury (PrAKI) continues to be a significant public health concern, con

academic.oup.com