Nikki Maphis, PhD
@neuronikki.bsky.social
Neuro nerd, current postdoctoral fellow trying to navigate the new abnormal, advocate for all, looking to change the face of science for good! How does alcohol use throughout the lifespan impact Alzheimer's disease risk? I'm trying to find out!
Hey @einsteinbros.bsky.social , thanks for the one plate and absolutely no knives for my morning meeting. Super helpful. Were those extra?
I have been a passionate researcher from the first time I touched a pipette, but my work and the work of hundreds of other scientists is at risk of ending because of the anti-DEI and anti-science rhetoric of the current administration. #neuroscience #postdoc 🧠
How does drinking alcohol shape the aging brain? @neuronikki.bsky.social studies how heavy drinking impacts neurons as we age. Research has shown that alcohol use disorder (AUD) in middle age increases the risk for developing Alzheimer's disease or other types of dementia - but how?
New pub alert: If alcohol is bad news for P301S (tauopathy mice) mice by accelerating gait impairments, spreading pathological tau and altering microglia morphology, what else is it doing to the adult brain? #postdoc 🧠 #neuroscience #alcoholresearch onlinelibrary.wiley.com/doi/10.1111/...
Alcohol consumption in P301S mice accelerates gait impairments, modifies aggregation of pathological tau and alters microglia within the hippocampus
Excessive alcohol use is a major modifiable risk factor for Alzheimer's disease (AD), yet its impact on tau pathology remains poorly understood. Using a voluntary drinking-in-the-dark (DID) paradigm,...
onlinelibrary.wiley.com
Thanks to the team @nature.com for telling our stories and amplifying our experiences. Science and scientists are still very much under attack! #standupforscience #neuroscience #postdoc
I’m always inspired by the work of my colleagues @dangaristo.bsky.social @maxkozlov.bsky.social and @heidiledford.bsky.social But I’ve got to say that this one is special. 🧪🧵6/6 www.nature.com/articles/d41...
Thanks to @acerjournal.bsky.social for publishing my recent article pubmed.ncbi.nlm.nih.gov/40755227/ Alcohol altera gait and accelerates pathological tau spread in a tauopathy model. Wait until you see what I did with the other half of the brain. More to come soon... 🧠 #neuro #postdoc
@ticketmaster.com was OOPS ALL Bots this morning. You're telling me 200,000 people were online trying to get Tix to see Sir Paul McCartney in ABQ, NM. What about the people that live here and are big Beatles fans? No we cannot afford $1,200 tickets. We spent an HOUR waiting for nothing. #robbery
Ashamed of #NIAAA for holding up these training grants across the country (it's not just ours). I thought training scientists to study #alcoholusedisorder and develop treatments and meaningful interventions is something the government actually wanted to fund? #postdoc
Today our @unm.edu @casaa.bsky.social T32 training grant is no longer funded. We are waiting for our renewal that is pending. I spent most of yesterday crying with worry about how I will support our amazing trainees. Today I celebrate them and the joy of seeing them present at CPDD and RSA. 🧵
I just found out my funding ends today. It is such a sad day. #NIAAA how many more programs and people will lose their jobs?
a man in a white shirt is sitting on the floor and says not like this .
ALT: a man in a white shirt is sitting on the floor and says not like this .
media.tenor.com
First @southwestair.bsky.social flight couldn't land and then had to do a quick pull up and circle. Now the second plane has driven around the airport sat for 20 min and now driven back to the gate. What is going on?
Yesterday's bench ruling by Judge Young feels like a dream, even though I know there is still so much to do, and we aren't done, yet. #resist #postdoc #scienceisforeveryone Thank you @aclu.org and @protectdemocracy.org and all of my co-plaintiffs for your support! www.aclu.org/press-releas...
Federal District Court Strikes Down NIH’s Unlawful Directives That Led to the Elimination of Critical Research | American Civil Liberties Union
BOSTON — In a major victory for public health, the U.S. District Court for the District of Massachusetts today struck down the National Institutes of...
aclu.org
Part the Cloud and the Association have just announced $5 million in new funding to support four cutting-edge studies focused on gene targeting therapies for Alzheimer’s. bit.ly/4l8yEVx
Alzheimer's Association Part the Cloud Grants $5 Million to Develop Gene Targeting Treatments
Through the Alzheimer's Association, the Part the Cloud grants support development of innovative gene targeting treatments for Alzheimer's and dementia.
bit.ly
Can you prevent Alzheimer's disease with our VLP immunotherapy? With the support of @alzassociation.bsky.social and the #PartTheCloudinititatve we will soon find out! www.alz.org/news/2025/al... Humbled and excited to witness my science baby grow up!
Alzheimer's Association Part the Cloud Grants $5 Million to Develop Gene Targeting Treatments
Through the Alzheimer's Association, the Part the Cloud grants support development of innovative gene targeting treatments for Alzheimer's and dementia.
alz.org
Happy grant submission day to those who celebrate! I remain steadfast and resilient while submitting this K99/R00 for the 3rd time. I can barely process, let alone explain the emotions, the doubt, the devastating grief, and the hope I've experienced throughout this entire process. #Neuro
a man in a fur hooded jacket talks to a woman with the words rebellions are built on hope
ALT: a man in a fur hooded jacket talks to a woman with the words rebellions are built on hope
media.tenor.com
The coolest stuff coming out of the LinsenLab, as per usual. Great work @neuromorning.bsky.social !!!!
Unsupervised Phenotyping Reveals Disrupted Neural Firing Characteristics in the Anterior Thalamus and Surrounding Brain Regions Following Third-Trimester Equivalent Alcohol Exposure in Mice https://www.biorxiv.org/content/10.1101/2025.06.02.657410v1
Amazing work being done by our amazing postdoc! Check it out!
New preprint in which we utilize UMAP to functionally cluster thalamic neurons to determine what, if any, firing rate and waveform properties are disrupted by third-trimester alcohol exposure
Cutting funding for research will have devastating consequences, unrealized for decades. The amount of talented and motivated early career scientists who really want these careers will not receive the training and/or financial support needed to get them there. #postdoc #standupforscience
2/n
Trump’s ‘fear factor’: Scientists go silent as funding cuts escalate | Science | AAAS We cannot and should not stay silent. Keep sharing your stories. #neuroscience #postdoc
Trump’s ‘fear factor’: Scientists go silent as funding cuts escalate
Many worry about retribution. But for others, speaking out is worth the risk
science.org
What a heart-rending, beautiful, enraging piece by #KseniiaPetrova as told to #AlexEllerbeck at the @nytimes.com. www.nytimes.com/2025/05/13/o...
Opinion | The Science I Would Be Doing if I Weren’t in ICE Detention
nytimes.com
On speaking about universities essentially bending the knee to the king he said, "and I think eventually they will..." If that doesn't sound like authoritarianism....yeesh. Nothing he says in this interview makes sense and in essence he attacks his interviewer. Everyone should read this.
In which the Senate-confirmed director of the National Institutes of Health - talks down to the highly experienced @jocelynkaiser.bsky.social - says "it's not me personally" who cancels agency grants - claims @nature.com is spreading rumors, hours before he confirms said rumors
Never stop telling your stories. Science is for everyone. #postdoc #standupforscience #neuroscience www.abqjournal.com/opinion/arti...
OPINION: Science cuts: The five stages of grief
The five stages of grief — denial, anger, bargaining, depression and acceptance — rarely happen in any specific order.
abqjournal.com
But this war is impacting ALL universities, especially our smaller hispanic-serving R1s in New Mexico, where dozens of graduate students are struggling with recent stop work orders and loss of funding and where our postdoc training program #IRACDA was also cancelled.
It's not just Columbia, it's not just DEI, and it's not just biomedical research: Trump's war on universities has frozen crucial science at institutions like Princeton, Cornell, Northwestern, and more. Our @nature.com team spoke to some of the affected scientists: www.nature.com/articles/d41...
Excited to be highlighted for the tour de force that is this paper from my dissertation work: #postdoc #alzheimers hscnews.unm.edu/news/unm-res...
UNM Researchers Plan Clinical Trials to Test Vaccine Against Alzheimer’s-Promoting Tau Protein
University of New Mexico Health Sciences researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau – a protein in the brain associated wi...
hscnews.unm.edu
Looks like notices of funding opportunities (NOFO) are more like Lack of opportunities (LOO). #postdoc #earlycareer #nocareer
I used to look forward to this NIH TOC of funding opportunities and notices every Friday. It was exciting to see what new directions the NIH was taking science and advancing healthcare. Now it just makes me want to cry. 😔
This needed to be said, and thank you for saying it.
the thing I hate most about that rfk quote is that autistic lives have value and worth and beauty and dignity whether they are able to do the things other people do or not. no one is defined by ability or lack thereof and to frame divergence as lack is monster stuff, utterly godless
Hoping to see more universities come together to stand up to fight these arbitrary cuts. #scienceisforeveryone #stopthecuts
Breaking News: Harvard rejected the Trump administration’s demands, including that it submit to monitoring and reduce the power of faculty and students.
Why am I standing up? This movement is about those who are unable to stand up for themselves and for the atrocities happening against our scientists, our science and the community our science serves. #scienceisforeveryone
Read more about our lawsuit on behalf of researchers, public health associations, unions, and a reproductive research organization challenging NIH’s cancellations of research grants, in partnership with @ACLU.org, @aclum.bsky.social, and @cspi.bsky.social. protectdemocracy.org/work/challen...
Saying that these programs "no longer effectuate agency priorities" is absolutely ridiculous. They are removing training opportunities from hundreds of committed, engaged and excited trainees at every single career stage. Absolute destruction. #postdoc #IRACDA www.thetransmitter.org/funding/excl...
Exclusive: NIH nixes funds for pre- and postdoctoral training programs
Many of the axed grants support scientists from underrepresented communities.
thetransmitter.org
Editing scientific findings because it doesn't fit a specific narrative is unacceptable. Neuro-omics databases should not be altered because your tax dollars paid for this research to be conducted through a budget approved and dictated by Congress. There are 3 branches of government.
Some troubling information A red banner appeared on the NeMO (The Neuroscience Multi-omic) webpage. "This repository is under review for potential modification in compliance with Administration directives." What effing Administration directives relate to a neurosciece multi-omic repository? 1/3
What's it like being a postdoc in DJT's America? If you're currently a postdoc comment 👇 with what you are going through! Work/Life balance, financial stress, funding issues, grants disappearing, amotivational, general sadness?