Two more recordings from the #SerialEM Community Meeting 2026 are available on our channel at vimeo.com/serialem : * D. Bollschweiler & T. Schaefer - [...] A Multi-User Service Facility Perspective on SerialEM * P. Kirchweger - Advances in cryo-STET: from 3D-cryo-STET to 3.5D- and 4D-cryo-STET

SerialEM Talks and Tutorials

SerialEM is a widely-used program that supports several kinds of automated acquisition from transmission electron microscopes: tilt series, single particle data,…

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The feedback from participants at the #SerialEM Community Meeting 2026 in April — and the future of this format — have been central topics in our recent discussions. (Photo by Daniel Bollschweiler)

New preprint🧊🔬Introducing LowDoseWizard—a guided SerialEM workflow for rapid, standardised cryo-TEM setup! Setting up low-dose can be slow & daunting, especially for new users. LowDoseWizard automates optics, camera, and alignment steps from minimal input — full setup in <15 min. #cryoEM #SerialEM

cryoEM papers@cryoempapers.bsky.social · 3mo ago

LowDoseWizard - rapid and standardised setup of low-dose cryo-TEM imaging in SerialEM www.biorxiv.org/content/10.64898/2026.05.05.722937v1 #cryoEM

Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit www.nexperion.net/semcm2026

Yesterday, we took microscopy to a whole new level! 🔬 Nexperion visited a local kindergarten to explore the amazing microcosmos with the next generation of scientists. Did not succeed to install #SerialEM on this microscope, though.

Any scikit-image fans in Vienna? The skimage team would like to meet in Vienna for a code sprint Aug 14-16 ahead of EuroSciPy. We'd super appreciate it if someone's workplace can host us! All we need is electricity, natural light, and (most important) walking distance to coffee. ☕️😂🙏

A map of European countries with the product they were the world's #1 exporter of in 2023 (found on Reddit, source unknown) ... if this is correct, I am really proud of our Czech neighbours (while Austria is exporting "flavoured water"?!).

"Yes hello, police? I'd like to report a murder?" [...] "No, it hasn't happened yet, but once I find out who did this..."

SPACEtomo v1.2 is online! github.com/eisfabian/SP... - Improved GUIs for lamella detection, target selection and CLEM registration make it the best target selection workflow for PACEtomo on any kind of lamella sample. - Easier installation and configuration Any feedback is much appreciated! :)

The #SerialEM source repositories are now available on github, in addition to Mercurial: bio3d.colorado.edu/SerialEM/#So...

I am already running a service to notify about new #SerialEM releases by email at nexperion.net/serialemupdatenotices, but considering to make this a Bluesky bot as well ... is this something the #teamtomo #cryoEM #cryoET community would be interested in?

Repost appreciated: Open #PhDposition in my group! Join us in Umeå, 🇸🇪 to uncover how arboviruses remodel the cellular interior. In situ #cryoET with great #virology and #biophysics collaborators. Customisable project. Application deadline 15 December. More info: www.carlsonlab.se/join/

Better late than never: no more excuses for losing essential #SerialEM configuration files - a video tutorial explaining file types, backup and restore strategies is now online at vimeo.com/1023251181

Backing Up a SerialEM Setup

This is "Backing Up a SerialEM Setup" by SerialEM Tutorials on Vimeo, the home for high quality videos and the people who love them.

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The first of a series of new #SerialEM tutorial videos is online - Autocontouring of Grid Squares. 🎉 Let us know what you think and what topics you would like to see covered in the future!

Autocontouring of Grid Squares

This is "Autocontouring of Grid Squares" by SerialEM Tutorials on Vimeo, the home for high quality videos and the people who love them.

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Last week's release of #SerialEM beta testing introduces "Multiple Grid Ops", an interface to auto acquire grid maps, square maps, and final data from multiple grids in a row using TFS/JEOL autoloaders - for details see bio3d.colorado.edu/SerialEM/bet..., feedback from early adopters is welcome!

Could one of my friends using #SerialEM share a full grid montage of a "typical" cryo SPA grid (including broken squares, thick ice, thin ice, ...). I'd need the nav and the mrc file to run some tests ...