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Nichole Bouffard

@nicholebouffard.bsky.social

SciPM @ Allen Institute | Former WashU Postdoc | PhD @ UofT 🇨🇦 | nicholebouffard.com 🏳️‍🌈 she/her

13 Posts207 Follower262 Folgt
Rayna Tang@raynatang.bsky.social · 2w ago

Excited to share that my first-ever first-author paper (w/ @atabk.bsky.social @AngeliqueDelarazan @zreagh.bsky.social) is now out in PNAS! Building a story to link two objects boosts associative memory and inference, but not memory for the objects themselves. www.pnas.org/doi/10.1073/... 🧵

Active linking through narratives facilitates associative inference | PNAS

In daily life, we often draw inferences about novel associations from prior experiences. This ability, associative inference, is thought to be a ke...

pnas.org

Catalina Yang@catalinayang.bsky.social · 4w ago

New paper out w/ Katherine Duncan and Morgan Barense! Why do some memories update when our expectations are violated, while others remain stable? What matters most is the strength of a memory at reactivation—not how old it is. And, I designed the cover! royalsocietypublishing.org/rstb/article...

Memory strength at reactivation, not memory age, governs prediction error-driven updating of naturalistic event memory

Abstract. Prediction error during memory reactivation is posited to be a key driver of memory updating. However, prediction error leads to varied memory ou

royalsocietypublishing.org

Alex Barnett@alexbarnett.bsky.social · 2mo ago

Happy to announce this work has been published www.nature.com/articles/s44... People can view the same event and recall it differently. Here we asked if two participants recall events similarly, where in the brain do they share event representations both at encoding and recall?

Natural language processing captures memory content associated with shared neural patterns at encoding and retrieval - Communications Psychology

This study shows that greater similarity in recalled content was associated with stronger shared activation patterns at encoding and retrieval in prefrontal and temporal cortices.

nature.com

Alex Barnett@alexbarnett.bsky.social · 11mo ago

New preprint! My stellar undergrad, June Kim, & @charan-neuro.bsky.social find that intersubject pattern similarity at encoding (especially in posteromedial cortex) relates to shared/differing content between Ss at recall (measured using topic modeling) www.biorxiv.org/content/10.1...

Yining Ding@liliand.bsky.social · 3mo ago

Our new paper on aging and temporal order memory (with @jzacks.bsky.social) is now out in Psych & Aging! Using a narrative paradigm, we found that older adults have preserved event-based memory organization and show greater knowledge-related benefits in temporal memory than younger adults. 🌟

Nichole Bouffard@nicholebouffard.bsky.social · 3mo ago

🚨 New Preprint 🚨 I’m excited to share the first paper from my postdoc. We found age differences in the timescales of neural activity in the hippocampus during movie viewing 👀 These timescales were related to memory specificity in an interesting way (spoiler: the hippocampus may not be special!?)

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 3mo ago

Age Differences in Hippocampal Neural Timescales During Movie-Viewing https://www.biorxiv.org/content/10.64898/2026.05.05.723065v1

Hayoung Song@hayoungsong.bsky.social · 5mo ago

Attention fluctuates over time and across contexts—how is this reflected in the brain?🧠 Fitting a dynamical systems model to fMRI data, we show that the geometry of neural dynamics along the attractor landscape reflects changes in attention. Out in @natcomms.nature.com www.nature.com/articles/s41...

Geometry of neural dynamics along the cortical attractor landscape reflects changes in attention - Nature Communications

Attention fluctuates over time and across contexts—how is this reflected in the brain? Fitting a dynamical systems model to fMRI data, Song and colleagues show that the geometry of neural dynamics alo...

nature.com

Adi Upadhyayula@adibuoy23.bsky.social · 5mo ago

1/ 🚨 New preprint Key Moments Scaffold the Semantic Structure of Narratives Using spoken recall and annotations from three naturalistic datasets with topic modeling, we ask: which parts of a narrative contribute most to its semantic structure and subsequently memory? Preprint: osf.io/dcfvw

OSF

osf.io

Hannah Tarder-Stoll@hannahtarder-stoll.bsky.social · 6mo ago

How do memories guide behaviour? Multiple memory representations, from detailed to gist-like, let us flexibly reconstruct or reproduce past experiences to behave adaptively across species. Now out in Physiological Reviews with Morris Moscovitch, Melanie Sekeres & @brianlevine.bsky.social!

Adaptive episodic memory: how multiple memory representations drive behavior in humans and nonhumans | Physiological Reviews | American Physiological Society

Episodic memory is a declarative long-term memory of a specific past experience. As such, it is multifaceted, encompassing both the objective and subjective components of that experience. These components can be flexibly represented at different levels of granularity, from precise, context-specific details to generalized, gistlike representations. In this review, we suggest that 1) multiple representations of an episodic memory at different levels of granularity are simultaneously encoded into a memory trace and 2) the relative weighting of these representations determines the extent to which a memory is reconstructed or reproduced at retrieval. We propose that this representational flexibility drives adaptive behavior by prioritizing reconstruction or reproduction depending on the age of the memory, its relationship to prior knowledge, current attentional goals or task demands, and individual differences. Drawing on research in humans and nonhuman animals, we show a close correspondence between psychological and neural representations of a memory across encoding, consolidation, and retrieval. Specifically, we discuss how hippocampal activity in humans and engram formation and activation in rodents support the reproduction of detailed memory representations, whereas schema formation across species, mediated by the medial prefrontal cortex, facilitates reconstruction and generalization to guide behavior. Finally, we consider how species- and individual-level differences shape episodic memory representations. By integrating findings across species, we illustrate how the correspondence between neural and psychological representations enables multiple memory representations to balance stability and flexibility, ultimately driving adaptive behavior.

journals.physiology.org

Shrew@shrewshrew.bsky.social · 6mo ago

People outside of Minnesota, in case you are wondering how to help the current situation, this website has many current opportunities to donate and support people who need help in Minnesota. Help pay rent, get groceries, and provide other support for people in hiding. www.standwithminnesota.com

Stand With Minnesota Donation Directory

Stand With Minnesota is a hub for supporting, learning, and taking action to support Minnesotans impacted by ICE and federal enforcement.

standwithminnesota.com

Mayor Zohran Kwame Mamdani@mayor.nyc.gov · 6mo ago

As tens of thousands across America protest the violence that ICE sows with impunity, federal agents shot and killed another person in Minneapolis today.

ICE terrorizes our cities. ICE puts us all in danger. Abolish ICE.

Mariam Aly@mariamaly.bsky.social · 9mo ago

How do changes in context influence how we organize our memories in time? Faster contextual changes are associated with faster drift in hippocampal activity and reduced temporal clustering in recalled memories. Elegant work led by @lindsayrait.bsky.social! www.jneurosci.org/content/45/4...

Hippocampal Drift Rate Reflects the Temporal Organization of Memories

When freely recalling past events, individuals tend to successively remember stimuli that were studied close together in time—a phenomenon known as temporal clustering. Temporal clustering is thought ...

jneurosci.org