Eitan Schechtman

@eitans.bsky.social

Asst prof at Dept of Neurobiology & Behavior + Center for Neurobiology of Learning & Memory @ucirvine.bsky.social Sleep, cognition & wellbeing 🛌💤🔀🧠. PhD: Hebrew U; Postdoc: Northwestern U. He/him. Views are my own & don't reflect those of my employers.

📣New paper! How does the sleeping brain help us to integrate new experiences while managing memories from the past? For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n www.nature.com/articles/s41... 🧪🧠📈👩‍🔬#OpenAccess

Experience reorganizes content-specific memory traces in macaques - Nature Neuroscience

In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep and can sometim...

nature.com

Can we study MTL ripples non-invasively? New preprint! We show that source-resolved MEG tracks ripple-like activity during sleep that: • localizes to the MTL • follows the canonical SO–spindle hierarchy • matches an iEEG benchmark • indexes memory reactivation www.biorxiv.org/content/10.6...

Non-invasive tracking of ripple-like activity during human sleep using MEG

Hippocampal ripples are considered a key mechanism of sleep-dependent memory consolidation. In humans, however, their direct investigation has relied on invasive recordings from patients with epilepsy...

biorxiv.org

Night-to-night sleep EEG variability over one year: We found that intra-individual night-to-night variation was low for spectral power, sleep duration, N2 and REM sleep; medium for N3 and macrostructure; and high for sleep cycle duration, wake and N1. www.biorxiv.org/content/10.6...

Night-to-night sleep EEG variability over one year

This study aimed to explore night-to-night variability of multiscale sleep patterns by analyzing subcutaneous electroencephalography (sqEEG) from 20 healthy participants over one year (205–388 nights ...

biorxiv.org

Looking to work with a postdoc. Prior experience with fMRI and computational modeling required, interest in psychiatry desired. Fellowship provides three years salary plus independent travel/equipment funds. Send CV and 2-3 manuscripts (preprints OK).

Check out our @royalsociety.org Philosophical Transactions B theme issue, "The role of hippocampal prediction: bridging perception and memory." Thanks to all our fabulous authors, and my co-editors @peterkok.bsky.social and @mariamaly.bsky.social who dreamed it up and kept the train on the tracks.

Peter Kok@peterkok.bsky.social · 4w ago

The hippocampus sits at the interface of perception & memory, allowing us to link past, present, & future through its role in generating predictions. Excited to share this theme issue in @royalsociety.org's Philosophical Transactions B, co-edited with @barense.bsky.social & @mariamaly.bsky.social

Very excited to share our new review on C-HORSE, our model of the hippocampus! We think there is very encouraging alignment between C-HORSE proposals and the extant empirical literature, though we also note plenty of areas for further model development. royalsocietypublishing.org/rstb/article...

Evidence for complementary learning systems within the hippocampus

Abstract. Decades of research have established the hippocampus as central to episodic memory, but growing evidence suggests that it also contributes to str

royalsocietypublishing.org

During sleep, neurons in the hippocampus 'replay' past activity patterns. This is thought to underlie memory consolidation 🧠 After a busy day, how does the brain sort out what is worth replaying? 🤔 Check out this preprint 📃 from Tirole, Duvelle and Bendor for answers! doi.org/10.64898/202...

Time, but not reward, shapes replay-based episodic prioritization

Why are some experiences remembered better than others? Leading theories propose that hippocampal replay prioritizes memories for consolidation according to their expected future value. We recorded hi...

doi.org

New preprint! We show low arousal states promote hippocampal ripple genesis in sleep and wake. This bridges rodent work, where ripples predominate during sleep, with human studies reporting ripples during active behavior, identifying low arousal as a common mechanism www.biorxiv.org/content/10.6...

Arousal state modulates human hippocampal ripples

Hippocampal ripples are transient, high-frequency oscillations linked to memory replay and consolidation. Ripples are well-characterized in rodents to occur during periods of behavioral inactivity (i....

biorxiv.org

🧠 New preprint! How well can current algorithms *actually* detect neural "replay" in the human brain under absolutely optimal conditions? We built FASTIMAGES: A combined MEG + fMRI benchmark with KNOWN neural sequences, so replay-detection methods can finally be validated against a ground truth.

FASTIMAGES: Validating replay detection methods in human neuroimaging

A combined MEG + fMRI benchmark dataset with known neural sequences to validate replay detection methods (TDLM and SODA).

cimh-clinical-psychology.github.io

Interested in human replay and solid methods? Jointly with @skjerns.de we're releasing a benchmark dataset with known ground-truth neural sequences in MEG & fMRI, for developing & validating replay methods. First test: existing methods show similar effect sizes, but room to improve shorturl.at/6TgIr

FASTIMAGES: Validating replay detection methods in human neuroimaging using a combined MEG and fMRI dataset

Studies in rodents and humans using invasive electrophysiology have established that neural replay is a ubiquitous phenomenon in the brain that is associated with a wide range of cognitive functions, ...

shorturl.at

New paper from our group: using simultaneous EEG-fMRI, we investigated the neural mechanisms underlying individual NREM sleep slow waves. Our findings suggest that slow waves are not a homogeneous phenomenon and may reflect distinct physiological processes. www.nature.com/articles/s42...

Thalamic involvement defines distinct slow-wave subtypes in NREM sleep - Communications Biology

Using simultaneous EEG-fMRI, we identify two types of NREM slow waves with distinct thalamic profiles. Large, synchronized waves involve early thalamic activation and arousal markers, whereas smaller ...

nature.com

I am recruiting an exceptional postdoc to join my lab at UC Irvine. Must be a productive researcher with experience in functional neuroimaging, network neuroscience, AI/ML, who is interested in aging, neuropsychiatric or neurodegenerative illness. www.linkedin.com/jobs/view/44...

UC Irvine hiring Postdoctoral Researcher in Irvine, CA | LinkedIn

Posted 12:31:04 AM. Postdoctoral Fellow – Neuroimaging, Network Neuroscience & AI/ML in Cognitive DisordersYassa Lab |…See this and similar jobs on LinkedIn.

linkedin.com