Nico Barros
@nicobarrosid.bsky.social
Transplant Infectious Diseases Indiana University
Cool article! @drboulware.bsky.social academic.oup.com/cid/advance-...
Revisiting Immune-Mediated Mechanisms as Drivers of Cryptococcal Immune Reconstitution Inflammatory Syndrome
Hyunah Yoon, MD MS, Liise-anne Pirofski, MD, David R Boulware, MD MPH; Revisiting Immune-Mediated Mechanisms as Drivers of Cryptococcal Immune Reconstituti
academic.oup.com
Addressing Antifungal Drug Resistance — A “One Health–One World” Challenge @grthompsonmd.bsky.social and Angel Desai www.nejm.org/doi/full/10....
Addressing Antifungal Drug Resistance — A “One Health–One World” Challenge | NEJM
Use of some antifungal pesticides may select for resistant fungi in the environment, which can then endanger human health. Coordinated regulatory processes in this area are important.
nejm.org
Cannot agree more with @germhuntermd.bsky.social @fungaldoc.bsky.social @natebahrid.bsky.social "Better awareness, diagnostic testing practices, and reporting are needed to improve patient outcomes and enhance our understanding of coccidioidomycosis epidemiology" jamanetwork.com/journals/jam...
Estimated Burden of Coccidioidomycosis
This cross-sectional study generates a systematic and rigorous estimate of national incident symptomatic coccidioidomycosis cases by developing a model to account for cases missed through national sur...
jamanetwork.com
Histoplasma working group ISHAM. Let's do it! 90-90-90 for 2030!
Interferon-γ therapy in patients with refractory disseminated #coccidioidomycosis Steve Holland and colleagues in @cidjournal.bsky.social academic.oup.com/cid/advance-...
Interferon-γ therapy in patients with refractory disseminated coccidioidomycosis
Abstract. Refractory disseminated coccidioidomycosis (DCM) is a severe disease with limited treatment options. This report reviews our own and prior publis
academic.oup.com
Benedict K. and colleagues estimate that the US fungal disease related economic burden to be 19.4 billion dollar (with Dr. Evil sound effect)!!! academic.oup.com/ofid/article...
Economic Burden of Fungal Diseases in the United States
We conservatively estimated the U.S. economic burden of fungal diseases as $11.5 billion in 2019: direct medical costs ($7.5 billion), productivity loss du
academic.oup.com
Saving the best for last, Histoplasma working group ISHAM2025 Foz do Iguaçu, Brazil
Michael Mansour presenting about "Augmenting neutrophil function as a therapeutic strategy for high risk-patients" Next level stuff! @mansourlab.bsky.social @mgh-id.bsky.social
journals.asm.org/doi/10.1128/... Great paper! @germhuntermd.bsky.social
Practical Guidance for Clinical Microbiology Laboratories: Antibody and antigen detection methods for dimorphic fungal infections | Clinical Microbiology Reviews
SUMMARYAntibody and antigen detection assays continue to play a significant role in the diagnosis of dimorphic fungal pathogens, including Blastomyces dermatitidis complex, Coccidioides immitis/posada...
journals.asm.org
Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter PK study for Screening Antifungal Exposure in Intensive Care Units (SAFE-ICU) J Roberts etc TLDR: ++variable, need tailored approach w TDM link.springer.com/article/10.1...
Update on the Clinical Practice Guidelines for treatment of Histoplasmosis. Thank you to all the authors @fungaldoc.bsky.social @germhuntermd.bsky.social @jobadd.bsky.social @iddoc4kids.bsky.social Nathan Bahr www.idsociety.org/practice-gui...
Histoplasmosis (2025)
idsociety.org
From rising #TxID star (and a Canadian, no less), Patrick Tam @tamckpatrick.bsky.social HOPE in every breath and heartbeat: Understanding transplant eligibility, access barriers, and clinical outcomes in thoracic transplantation in persons with HIV www.jhltopen.org/article/S295...
HOPE in every breath and heartbeat: Understanding transplant eligibility, access barriers, and clinical outcomes in thoracic transplantation in persons with HIV
Persons with HIV (PWH) are living longer, leading to increased end-organ disease from chronic illness. Organ transplantation improves survival in patients with end-organ disease yet remains a constrai...
jhltopen.org
Histoplasmosis screening was positive in 9.1% of PLWHIV with clinical manifestations suggestive of histoplasmosis (including fever, night sweats and weight loss) in a Brazilian center. More screening is required for early diagnosis and improved outcomes. academic.oup.com/mmy/advance-...
Histoplasmosis screening using urinary antigen detection in people living with HIV in Southern Brazil
Abstract. Histoplasmosis is a life-threatening opportunistic infection in individuals with advanced HIV disease (AHD), particularly in endemic regions such
academic.oup.com
Fungal sensitization syndrome may be more prevalent than currently thought. This article examines asthma as a potential coccidiodiomycosis complication. onlinelibrary.wiley.com/doi/10.1111/...
Investigating Asthma After Coccidioidomycosis Among Patients With Commercial Health Insurance, United States, 2017–2022
Background The relationship between asthma and coccidioidomycosis has not been fully described. We have hypothesised that Coccidioides could trigger inflammatory airway responses, similar to other f...
onlinelibrary.wiley.com
If it's written by @kottonnelson.bsky.social, it is a must read! Concise expert insight into the utility of Immune monitoring assays for Cytomegalovirus. journals.lww.com/transplantjo...
Immune Monitoring Assays: Predicting Cytomegalovirus and... : Transplantation
An abstract is unavailable.
journals.lww.com
A must read...amazing collaboration between different societies Super good article. Plus it has Michael K. Mansour @mansourlab.bsky.social as an author, boom!! www.thelancet.com/journals/lan...
Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM
Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidias...
thelancet.com
One of the largest reports on pediatric histoplasmosis. academic.oup.com/jpids/advanc...
Retrospective Investigation of Pediatric Histoplasmosis Diagnosed at a Tertiary Children’s Hospital in an Endemic Area over 11 years
AbstractBackground. Most histoplasmosis data are from adults. We describe pediatric histoplasmosis diagnosed at a tertiary pediatric care center in an ende
academic.oup.com
This is a great commentary challenging the use of antibiotics for SBP prophylaxis in patients with cirrhosis. academic.oup.com/cid/advance-... I've added this review article by @arunasubramanian.bsky.social as it provides context to the question (great read). journals.lww.com/hepcomm/full...
Rethinking Antibiotic Prophylaxis for Spontaneous Bacterial Peritonitis in Patients with Cirrhosis: First, Do No Harm
Abstract. Antibiotic prophylaxis for spontaneous bacterial peritonitis (SBPPr) in patients with cirrhosis has been considered standard of care since the 19
academic.oup.com
Expanding our pool (and knowledge) Great article about the long term outcome of HBV viremic allograft use in seronegative liver and kidney transplant recipients. journals.lww.com/journalacs/a...
Friend or Foe? Safety and Efficacy of Hepatitis B Viremic... : Journal of the American College of Surgeons
T+ and NAT-negative (–) allografts in seronegative recipients. Study Design: All recipients of an HBV core antibody-positive (HBcAb+) LT or KT were prospectively evaluated at a single transplant ce...
journals.lww.com
Two good reads to accompany the Saturday morning coffee: doi.org/10.1093/ofid... (Breakthrough invasive mold infections in hematological cases) academic.oup.com/ofid/article... (Adenovirus incidence on pediatric SOT)
Breakthrough Invasive Mold Infections in Hematologic Cases: Relevance of the Host's Factors
This retrospective study evaluating breakthrough invasive mould infections occurring among hematological patients highlights that host factors, including p
doi.org
Fun things to read and keep us entertained during these difficult times. "Surveillance and prevention of infection in clinical xenotransplantation" journals.asm.org/doi/10.1128/... Amazing article by Adam Stewart and Jay Fishman
a baby anna from the movie frozen is surrounded by snow
Alt: a baby anna from the movie frozen is surrounded by snow
media.tenor.com
Check out our editorial "Beyond the test: moving forward with transplant candidates testing positive for COVID-19" Since I wrote it with @kottonnelson.bsky.social, can I say that I'm a grownup, or not just yet? We discuss an interesting Transplantation article: journals.lww.com/transplantjo...
What an awesome start for cocci this 2025! Outcomes of cocci in Ab+ SOTs after stopping antifungal prophy journals.lww.com/transplantjo... Antifungal prophy for Cocci: how long journals.lww.com/transplantjo... Should we treat mild cocci in immunocompetent host academic.oup.com/cid/advance-...
Journal of Fungi review of #Histoplasmosis in solid organ #transplant by @nicobarrosid.bsky.social and L. Joseph Wheat of MiraVista Labs 🚨Open access🚨 🔥Great tables!🔥 Open Access articles always prioritized by transplantid.net https://buff.ly/4aovOY7
This guideline sought to provide updated recommendations on corticosteroid use for adults with sepsis, ARDS, and CAP jamanetwork.com/journals/jam...
Corticosteroids for Sepsis, ARDS, or Community-Acquired Pneumonia
This JAMA Clinical Guidelines Synopsis summarizes the 2024 Society of Critical Care Medicine guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired...
jamanetwork.com
#vaccinesavelives Expanded recommendations to include pneumococcal conjugate vaccination for adults >50. www.cdc.gov/mmwr/volumes...
Expanded Recommendations for Use of Pneumococcal ...
This report describes CDC’s updated pneumococcal conjugate vaccine recommendation for all adults aged ≥50 years who are PCV-naïve or who have unknown vaccination history.
cdc.gov
Geographic distribution of endemic mycoses 2.0! Let's leave the "historical distribution maps" in the history books and replace them for 21st century driven data. @fungaldoc.bsky.social @julioczuniga1.bsky.social academic.oup.com/ofid/advance...
Infectious Diseases Clinics of North America just published reviews of: Histo, Blasto, Mucor, Dematiaceous, invasive candidiasis, climate change medical mycology, fungal nomenclature, and culture-independent diagnostics. www.sciencedirect.com/journal/infe...
Infectious Disease Clinics of North America | ScienceDirect.com by ElsevierScienceDirect
Read the latest articles of Infectious Disease Clinics of North America at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
sciencedirect.com