Nicole Fisher

@nicolefish.bsky.social

UCSF postdoc in the von Zastrow lab - interested in the intersection of GPCR biology and neuroscience 🧠🔬👩‍🔬

I'm excited to share the first work from my postdoc in the von Zastrow lab! We address a fundamental question about neuromodulatory signaling: Can neurons tell the difference between multiple neuromodulatory inputs when they converge on only a few receptor pathways? www.biorxiv.org/content/10.6...

Temporal coding expands the bandwidth of GPCR-mediated neuromodulation

The advent of modern transcriptomic approaches has revealed a breadth of neuromodulatory G protein-coupled receptor (GPCR) co-expression far exceeding what was previously thought. This raises a fundam...

biorxiv.org

Excited to share my first paper from my postdoc! In this study, we demonstrate that the mu opioid receptor produces a second wave of G protein activity on endosomes in a manner that doesn’t require receptor internalization. Check it out! www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

pnas.org