Nicki Perry-Hauser
@nicoleperryhauser.bsky.social
📚 Lecturer (Research & Teaching) @UniGlasgow | 🧠 CUIDS Postdoc @Columbia 🎓 PhD in Pharmacology @Vanderbilt | 🔬 Adhesion GPCRs & Neuropsychiatric Disorders | 🌟 Leading Edge Fellow
Check out the lab’s latest work! Very excited to be in Melbourne to present our findings @monashuniversity.bsky.social
Neuropsychopharmacology@npp-journal.bsky.social · 2mo agoPerry-Hauser et al. find the loss of ADHD-linked receptor latrophilin-3 (ADGRL3) increases dopamine release in brain slices but reduces it in behaving mice, suggesting ADGRL3 may control where dopamine is released rather than how much @nicoleperryhauser.bsky.social www.nature.com/articles/s41...
First corresponding author paper published today! We review steroids as generalizable ligands for adhesion GPCRs. Congrats to the team bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
BPS Publications
Emerging evidence suggests steroids may act as generalizable ligands for adhesion GPCRs, a receptor class with considerable pharmacological potential. While most studies have focused on the ADGR‘G' s....
bpspubs.onlinelibrary.wiley.com
Very excited to have my first faculty grant funded by Tenovus Scotland (tenovus-scotland.org.uk). Thank you for supporting my work!
Medical research charity | Medicine | Healthcare | Tenovus Scotland
Tenovus Scotland provides vital funds for early stage medical research in Scotland. One of Scotland’s leading medical research charities, it supports pilot projects and new research talent across Scot...
tenovus-scotland.org.uk
Exciting PhD Opportunity at the University of Glasgow! I’m thrilled to share that my PhD project with @mickcraig.bsky.social has been shortlisted for the College Future Themes PhD Programme within the College of Medical, Veterinary & Life Sciences (MVLS).
A new special issue entitled “Emerging Voices in GPCR Biology” is now available in Molecular Pharmacology, highlighting innovative research led by early-career investigators (ECIs) across key areas of G protein-coupled receptor (GPCR) science. www.sciencedirect.com/science/arti...
Emerging Voices in GPCR Biology
sciencedirect.com
🚨PhD Studentship Opportunity in the Perry-Hauser Lab – University of Glasgow🚨 I’m recruiting a PhD student to join my lab through the NorthWestBio Doctoral Training Programme, under the theme of Underpinning Bioscience Discovery. www.gla.ac.uk/postgraduate...
✨ The Art of Open Science ✨ This beautiful crossstitch was created by Leah Blankenship, an undergraduate student at the @uoregon.bsky.social! This meticulously embroidered art uses data from our Allen Brain Reference Atlases. #OpenScienceWeek
Had a lovely time at the inaugural GPCR-UK meeting in Cambridge. Beautiful city and great science!
Now this is science publishing at its finest!
International Brain Laboratory@intlbrainlab.bsky.social · 12mo agoTwo flagship papers from the International Brain Laboratory, now out in @Nature.com: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
The 5th Transatlantic ECI GPCR Symposium is today at 10AM EDT (3PM BST)! Good luck to organisers Janelle Lanham, Tomasz Steniewski, and Edda Matthees. You can still register to attend this virtual, FREE event: event.fourwaves.com/gpcr2025/pages
5th Transatlantic ECI GPCR Symposium
Fourwaves - 5th Transatlantic ECI GPCR Symposium
event.fourwaves.com
Had a wonderful experience at the Scottish Neuroscience Group meeting in Dundee! Great series of talks and nice to hear about all the research.
Organized scientific fraud is growing at an alarming rate phys.org/news/2025-08... #ethics #research #science #fraud
Organized scientific fraud is growing at an alarming rate, study uncovers
From fabricated research to paid authorships and citations, organized scientific fraud is on the rise, according to a new Northwestern University study.
phys.org
(1/2) @maddipow.bsky.social draws an interesting comparison here regarding #PeerReview. I think this could really benefit bad reviews but probably not rogue reviews - the latter consisting of bias, rudeness & deliberate mishandling! One thing it underscores - Peer review training is essential!
Dr Madeleine Pownall@maddipow.bsky.social · last yr.I can never understand why efforts to improve peer review don’t learn from the decades of educational research about how to do good, robust, constructive assessment and feedback. What would happen if we treated peer review as pedagogy? New in @wonkhe.bsky.social wonkhe.com/blogs/peer-r...
🚨 New preprint alert! 🚨 Excited to share my latest work, now on bioRxiv: “Altered striatal dopamine regulation in ADGRL3 knockout mice” 🔗 www.biorxiv.org/content/10.1...
Altered striatal dopamine regulation in ADGRL3 knockout mice
Dopaminergic signaling is essential for regulating movement, learning, and reward. Disruptions in this system are linked to neuropsychiatric disorders such as ADHD. ADGRL3, an adhesion G protein-coupl...
biorxiv.org
Inspired by @mbeisen I've begun an experiment in open science. We are sharing our ongoing work on psychedelic signaling here: open.substack.com/pub/zendudes... I've decided to make this 'open' as the experiment are of immediate interest to the field and I'll write them up later.
An experiment in 'open science'
Why isn't Br-LSD psychedelic?
open.substack.com
The role of dopamine-sensitive motor cortical circuits in the development and execution of skilled forelimb movements https://www.biorxiv.org/content/10.1101/2025.06.20.660525v1
Cholinergic modulation of dopamine release drives effortful behavior https://www.biorxiv.org/content/10.1101/2025.06.18.660394v1
Adhesion GPCR community! We have a new SLACK workspace for aGPCR enthusiasts. Please reach out to me if you would like the link!
Dopamine Decoded: 5 Myths, 10 Facts | Psychology Today www.psychologytoday.com/us/blog/betw... With yours truly 😊🧪👩🏼🔬
Dopamine Decoded: 5 Myths, 10 Facts
What does dopamine actually do? A neuroscientist breaks down the science and clears up common misconceptions.
psychologytoday.com
Excited to present my work at the Inaugural GPCR-UK Network Meeting this September in Cambridge: gpcr-uk.org/programme/. Thank you to the organizers for putting together such a fantastic programme! Looking forward to meeting new GPCR enthusiasts and connecting with UK-based investigators. 🇬🇧
Programme – GPCR-UK
gpcr-uk.org
Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...
In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors
Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex netwo...
science.org
⏰ Check out this inspiring pair of articles from @paulmasset.bsky.social and Margarida Sousa! Some dopamine neurons care about rewards far in the future more than others, allowing the brain to learn the timing of future rewards. Congrats to the authors! 🍾 🔓 links: rdcu.be/epxkE rdcu.be/epxkG
A multidimensional distributional map of future reward in dopamine neurons
Nature - An algorithm called time–magnitude reinforcement learning (TMRL) extends distributional reinforcement learning to take account of reward time and magnitude, and behavioural and...
rdcu.be
Exploring Heidelberg after the EMBO Lab Leadership session. Feeling very lucky to be here!
During Q&A, whenever someone asks a question about our "mice."
It was something I had to seriously consider become I made the change! Certainly a barrier
Thiago Carvalho@cyrilpedia.bsky.social · last yr.“The visa fees are so exceedingly high that it makes coming here very difficult for some people. We are fishing for the best scientists in the world. They want to come and work here because we are such an effective country at science, but if we have these high costs, they can and will go elsewhere.”
We've had advances in green genetically encoded Ca2+ indicators (GECIs), but what about red-shifted GECIs? @piatkevich.bsky.social &co present SomaFRCaMPi, a new soma-localized red #GECI that exhibits improved accuracy & sensitivity for in vivo neuronal imaging @plosbiology.org 🧪 plos.io/3YnCqRW
