Nihar Desai MD, DM

@nihardesai7.bsky.social

Bone marrow transplant physician at the Princess Margaret Cancer Center, Toronto • Love wildlife, classic rock, and common sense medicine • Follow to learn hematology ❤ @nihardesai89 on that Elon app 🤷🏼

What doesn’t evolve, goes extinct!! If you don’t adapt new data, you’ll never improve patient care. No study is perfect, and none ever will be. What matters is critical appraisal of available literature and adapting it to improve patient care 🙏🏽

Can a D-dimer be used to diagnose DVT/PE? NOOOOOOOOOOOOOOOOOOOO! What else ⤴️D-dimer? •Any infection •Any inflammation •Old age •Cancer Remember, D-dimer is a very sensitive test but NOT a very specific test 🙌🏽

Anemia in CKD 👇🏽 We all know that CKD = ⤵️EPO What's the mechanism? The interstitial cells transdifferentiate into MYOFIBROBLASTS instead of EPO producing cells ⤵️ EPO producing cells = ⤵️EPO = Anemia 👇🏽

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In a single-group, single-center study, clearance of driver mutations 30 days after bone marrow transplantation predicted long-term disease-free survival in patients with myelofibrosis. Read the full study results: nej.md/4fQNdKn #MedSky

Clearance of Driver Mutations after Transplantation for Myelofibrosis | NEJM

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation cl...

nej.md

I’ve cared for infants who stopped breathing w/ pertussis. School aged kids who died of flu or COVID. And many of my patients can’t be vaccinated because they’re on chemotherapy or are immune compromised. Vaccinations save lives of those who get them & those who cannot. It’s that simple.

Skepticism is healthy. Over-skepticism stifles progress. It's important to know where to draw the line! It's also important to not comment on trials outside of one's area of specialization. It's impossible to understand the nuance of a disease you don't treat!