Hoping to innovate community population-level AMR surveillance with the ALARUM team bmjopen.bmj.com/content/16/2.... Can we use metagenomics of pooled colonisation samples to predict clinical AMR burden & inform antimicrobial guidelines?

Are you a post-doctoral microbiologist interested in characterising bacterial resistance evolution and want to apply your knowledge and expertise to developing new therapeutics for Klebsiella (and other Enterobacterales) infections? Then we need you! Apply now bit.ly/3MX39Ce close date March 13th 👀

🚨 Fully‑funded PhD for Home Students🚨 We'll explore non-antibiotic alternatives in relatistic environments, uncovering how they work, if they affect antibiotic activity and whether they influcence AMR acquistion. Come join a wonderful supervisory team! #MicroSky #UTISky #AMar tinyurl.com/38u552bu

🚨 New pre-print! 🚨 In the largest study of its kind to-date, we investigate the ecological and evolutionary mechanisms driving within-patient evolution of antimicrobial resistance (AMR). Read here: www.biorxiv.org/content/10.6... , and follow along with this thread, discussing our findings (1/21)

If you're interested, click on www.ox.ac.uk/admissions/g... - Life and Medical Sciences, Clinical Medicine 04!

UNIQplus projects | University of Oxford

Projects available for entry in 2026As part of your UNIQplus Research Internship, you will be working on a project under the supervision of academic staff from our community of world-leading

ox.ac.uk

Modernising Medical Microbiology@modmedmicro.bsky.social · 6mo ago

MMM has an exciting UNIQ+ project running this summer -apply now! Bacteria, microplastics & resistance — what’s the connection? #Microplastics are everywhere, even in hospitals. But what happens when bacteria stick to them? Come and find out! @afswinkels.bsky.social @nstoesser.bsky.social

By Shireen Kotay/Amy Mathers - Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance rdcu.be/e1uTu. Effects akin to gut microbiome dysbiosis/loss of colonisation resistance. To mitigate these reservoirs we need better evidence to understand what works best where.

Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance

npj Antimicrobials and Resistance - Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance

rdcu.be

Our project "Sardinia’s Invisible Marine Microbiome" is one of six 2026 #PartArt4OW participatory art initiatives! Excited to do this with the brilliant @annadumitriu.bsky.social (image credit), Sardinian scientists, citizens of Alghero, and colleagues in @modmedmicro.bsky.social @bashthebug.net

Delighted to be involved in the Gram-Negative Antibiotic Discovery Innovator (Gr-ADI) consortium novonordiskfonden.dk/en/news/new-... as part of a project led by Annette von Delft gcgh.grandchallenges.org/grant/discov... @modmedmicro.bsky.social @samlipworth.bsky.social @philipwfowler.bsky.social

Discovery of Novel Klebsiella Hits Through In-Depth Genomic Profiling, Fragment-Based Drug Design and Accumulation Assays

Annette von Delft and collaborators Nicole Stoesser, Lizbe Koekemoer, Ed Griffen, Paul Brennan, Frank von Delft, Phil Fowler, and Thomas Lanyon-Hoggat of the University of Oxford in the United Kingdom...

gcgh.grandchallenges.org

Univ of Oxford UNIQ+ scheme applications open: 7-week research internship this Summer www.ox.ac.uk/admissions/g.... Lots of projects - one in our lab on microplastics & AMR & hospital environments at @modmedmicro.bsky.social led by Aram Swinkels www.ox.ac.uk/admissions/g... (Clin Med 04). Join us!

What is UNIQplus? | University of Oxford

The UNIQplus programmeThe UNIQplus programme is aimed at supporting talented undergraduates from under-represented groups, who would find continuing into postgraduate study a challenge for reasons

ox.ac.uk

New out by @dotnagy.bsky.social & colleagues synthesising published epidemiological/microbiological/genomic data on 'big 5' CPE hospital outbreaks: www.medrxiv.org/content/10.6... Lots of them, but sampling and reporting heterogeneity makes it hard to nail risk factors for dissemination.

Our team wore blue for World Antimicrobial Awareness Week 2025💙 Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance. #WAAW @oxfordbrc.bsky.social

Pleased to see this out today in @lancetmicrobe.bsky.social www.sciencedirect.com/science/arti.... We estimate the independent effects of AMR genes on MIC at a drug-bug level and challenge the idea that resistance is a binary phenomenon.

Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli: an observational study

Surveillance and prediction of antibiotic resistance in Escherichia coli relies on curated databases of genes and mutations. We aimed to quantify the …

sciencedirect.com

Now published in @natcomms.nature.com 🎉 www.nature.com/articles/s41... With Gillian Rodger, @nstoesser.bsky.social, @samlipworth.bsky.social, @stat-sarah.bsky.social, and many others!

Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase - Nature Communications

This study found E. coli phylogenetic background shapes TEM-1 beta-lactamase expression and co-amoxiclav resistance. Phylogeny alone shifted isolates from susceptible to resistant, stressing a need for lineage-sensitive genotype-phenotype prediction.

nature.com

Will Matlock@wtmatlock.bsky.social · 2y ago

🚨 New preprint! 🚨 We reveal that blaTEM-1 expression varies across the E. coli phylogeny, driving differences in co-amoxiclav resistance: www.biorxiv.org/content/10.1...

Pleased to see this pre-printed, highlighting the completeness/accuracy of @nanoporetech.com long-read genome assembly for clinical Enterobacterales: www.biorxiv.org/content/10.1... Thanks to colleagues @modmedmicro.bsky.social, @ukhsa.bsky.social, @genewiz.bsky.social and @oxfordbrc.bsky.social!

Job opportunity for microbial genomicists interested in E. coli and Klebsiella infections and AMR 👀⬇️ - do get in touch if you might be interested! Closing date 7th Oct.

Sam Lipworth@samlipworth.bsky.social · 11mo ago

Come and work with Nicole Stoesser and I in Oxford with the fantastic team @modmedmicro.bsky.social - great opportunity for a postdoc in microbial genomics to do some creative research with great datasets as part of our HPRU. my.corehr.com/pls/uoxrecru...

Great new opportunity to work with #Liamshaw and @mutantbug.bsky.social as part of our HPRU collaboration (www.expmedndm.ox.ac.uk/research/hpr...) - sinks, phages, wastewater genomes, novel threat detection bit.ly/45Wcv6I - deadline 14th Sept 👀

New analysis from Kevin Chau @modmedmicro.bsky.social for the SinkBug Consortium (a collaboration with teams across 29 UK hospitals, NITCAR, UKHSA): Pathogen and AMR gene burden in 287 hospital sink-trap metagenomes and factors associated with high burdens.

medRxivpreprint@medrxivpreprint.bsky.social · last yr.

The hospital Sink-ome: Pathogen and antimicrobial resistance gene burden in sink-traps across 29 UK hospitals and associations with sink characteristics https://www.medrxiv.org/content/10.1101/2025.07.25.25332191v1