#openscience in action/ Using the Allen Brain Cell Atlas, Sora Mitamura is uncovering new insights into the cellular organization and gene expression patterns of the ventral striatum through computational analysis. Explore the ABC Atlas: brain-map.org/bkp/explore/

23 years ago today on Sept 16, 2003, we set out to build an open map of the brain & give it away free. Today we span cell science, immunology, neural dynamics, synthetic biology, AI biodesign, and more. For #OpenScienceWeek today, we're taking you inside the moments that made us.

Leveraging the structure and freedom of the Shanahan Fellowship, @irisstone.bsky.social built a new deep-learning method that can highlight potential targets for Alzheimer’s therapies. 🔗 https://alleninstitute.org/news/finding-alzheimers-targets-one-cell-type-at-a-time

How does your brain know the second something around you changes? 👀🧠 Scientists eavesdropped on 75,000+ neurons in the mouse brain to find out and they’ve publicly shared the data for anyone to explore: https://www.cell.com/cell/fulltext/S0092-8674(26)00745-2

Map of spiking activity underlying change detection in the mouse visual system

Large-scale Neuropixels recordings across the mouse visual system during an image-change detection task map how sensory, motor, and task engagement signals are distributed across the cortex, thalamus,...

cell.com

Boston, we're coming to you! Join us at MIT for an interactive workshop on how to explore and use cell type taxonomy data and tools from the Brain Knowledge Platform. 🎟️ Registration is free 🔗 https://connect.alleninstitute.org/e/exploring-cell-types-with-the-allen-institute-boston-2026

An associate editor of Frontiers in Systems Neuroscience has resigned in protest of the publisher’s artificial-intelligence system, arguing that its misuse is undermining academic integrity at the journal. By @dalmeet.bsky.social www.thetransmitter.org/publishing/e...

Neuroscience journal editor resigns over automation concerns

The editor resigned after the journal’s AI system overrode his selection of referees for a manuscript. His move prompted an internal review of the system.

thetransmitter.org

Spinal motor neurons in dazzling detail. ✨ Each green dot is a spinal motor neuron - crucial but rare cells making up just 1% of neurons in the spinal cord. In diseases like ALS, they are selectively damaged, making them of special interest to neuroscientists. #neuroskyence #FluorescenceFriday

Meet MapMyCells! This tool saves brain researchers precious time by comparing their data to massive, high-quality reference datasets, including our Alzheimer's and whole mouse brain atlases. 🔗 https://portal.brain-map.org/atlases-and-data/bkp/mapmycells

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for five brain diseases. #neuroskyence By @callimcflurry.bsky.social www.thetransmitter.org/treatments/a...

Allen Institute sets sights on treatments for brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and genetic tools to develop treatments for five brain diseases.

thetransmitter.org

Over two decades ago, Jeff Carroll learned he carries the gene for #Huntingtons, the same disease that took his mother. Instead of stepping back, he stepped toward it. Today he's part of our new Brain Health accelerator. His story, by @carolynjohnson.bsky.social: https://wapo.st/3Qi9GJp

Brain disease is tragic, but it doesn’t have to be. It’s time for a new approach to #brainhealth research. That’s why we and our partners are launching the Brain Health accelerator. 🎥 youtu.be/wnTG5Sg8AKY?...

Brain Health accelerator: a new way to study brain disease to find new treatments for it

YouTube video by allen institute

youtu.be

A global team of engineers and scientists has combined optical stimulation with a highly sensitive recording probe into one tool: Neuropixels Opto. Shared in @natmethods.nature.com, it allows researchers to measure, record, and manipulate brain cells. 🔗: https://bit.ly/3PxrwYI

The application deadline for the #LakeConference on Comparative and Evolutionary Neurobiology is approaching quickly! Apply by June 5 to be considered for this research forum on the beautiful shores of Lake Washington. All career stages welcomed. 🔗 https://bit.ly/4uZW5VE

The BRAIN Initiative has changed neuroscience, yet there is still a lot we don't know about the brain. BRAIN Initiative Director John Ngai shares a roadmap for the next decade and what's needed to achieve the next human health breakthroughs: https://bit.ly/4nVbmVP #studyBRAIN

🏆 Award-winning storytelling for world-changing science. PRSA has given a Bronze Anvil Award to our Editorial & Media Team for their campaign sharing last year's historic MICrONS data release. Experience the story: https://bit.ly/4nAbidM 🔬 Viz courtesy of our EM team and @quorumetrix.bsky.social

Troponin I (slow skeletal) is our #CellLineOfTheWeek! ❤️🔬 Our human stem cell lines & plasmids are openly available to reduce the barriers to scientific discovery. 🧫🚀 📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social

This vibrant video by our Immunology team shows how similar millions of cells are to one another. Each tiny dot represents a single cell; and their color, the cell type: cyan for intestinal cells, red for T cells, white for liver cells, orange for smooth muscle cells.

Salaries for workers across universities in Argentina have dropped 30 to 40 percent since Javier Milei took office, creating a scientific crisis that has driven researchers to the streets. #neuroskyence By @natmesanash.bsky.social, @claudia-lopez.bsky.social www.thetransmitter.org/funding/fund...

Science defunding in Argentina sparks new wave of protests

Scientists are protesting the government’s failure to restore previously cut scholarships and update salaries as required by a 2025 law.

thetransmitter.org

Happy #TeacherAppreciationDay to all the educators who inspire the next generation. Explore the resources, field trips, and professional development opportunities built around our real open science data: https://alleninstitute.org/education

Our own Bosiljka Tasic will be presenting at @ucicncm.bsky.social's 2026 Summer Conference on Neural Circuits in Health and Disease. 🧠📈 Learn more and register: https://cncm.medschool.uci.edu/2026-cncm-conference/

The Orange Cat Brain Atlas is here. 🧠🐈 Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."

WE'RE LIVE PAL (on ios)!!!!! Eras of Wrestling, the wrestling management simulation game i drew EVERY SINGLE WRESTLER for is now available for download! apps.apple.com/us/app/eras-...

The dorsal horn’s development was a ‘black box.’ Scientists have cracked it open. By @natmesanash.bsky.social #neuroskyence www.thetransmitter.org/developmenta...

Cell atlas cracks open ‘black box’ of mammalian spinal cord development

The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.

thetransmitter.org

New to using Jupyter notebooks for the Allen Brain Cell Atlas? Join us on Feb. 11 for a beginner-friendly webinar focusing on installation, set-up, and common questions. Register for the meeting link and recording: https://alleninstitute-org.zoom.us/webinar/register/WN_q0sJzndpRbSZWjrSGblu6A#/

You have less than a week to apply for the Summer Workshop on the Dynamic Brain in the gorgeous San Juan Islands! Apply by February 1 to be considered for this 2-week residential course and deepen your data analysis and computational skills. 🔗 https://bit.ly/4samKOZ

Summer Workshop on the Dynamic Brain 2026

The Summer Workshop on the Dynamic Brain is an intensive, project-based residential course with a focus on the neurobiology of sensory processing, coding, and neural population dynamics.

alleninstitute.org

Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers. Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social

US science after a year of Trump: what has been lost and what remains

A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.

nature.com

Congratulations to our own Marla Glass on receiving an Arthritis Foundation Rheumatoid Arthritis Research Program grant! Glass and her team will leverage the support into insights into the role of B cells in the progression of RA.

We're funding more high-impact projects – conceptualized by our internal teams – that push the boundaries of science through our inaugural Innovation Awards. Bold ideas to fuel breakthroughs of tomorrow: https://alleninstitute.org/news/allen-institute-announces-inaugural-innovation-awards-winners/

Looking for a New Year’s resolution? Learn to code! Need convincing? @analog-ashley.bsky.social co-leads our python workshop for educators and is here to hype you up! Educators, learn more the workshop and travel support: https://alleninstitute.org/events/educator-coding-workshop-2026/ #iTeachBio