Not AI, or maybe it is … - at minimum a new way to explore symptoms 😘

”Plasma measures of p-tau217 can accurately identify individuals in the preclinical stage of Alzheimer disease where interventions are likely to have the most benefit in delaying or stopping disease progression.”

Plasma p-Tau217 and Amyloid Burden in Older Adults Without Cognitive Impairment

This meta-analysis examines data for the accuracy of plasma phosphorylated tau 217 tests from published studies that compared older adults without cognitive impairment who were amyloid positive vs amy...

jamanetwork.com

An implant that cures blindness, fantastic news for AMD patients! This could bring bionic sight within reach.

People with blindness can read again after retinal implant

An electronic eye implant has restored vision in people with blindness caused by age-related macular degeneration.

nature.com

'The Pitt' Has Inspired More Organ Donation and End-of-Life Planning | Michael Schneider for Variety (@Variety) https://variety.com/2025/tv/news/the-pitt-organ-donation-end-of-life-planning-study-1236562186/

‘The Pitt’ Has Inspired More Organ Donation and End-of-Life Planning, According to USC Norman Lear Center Study

After just one season, Emmy-winning drama “The Pitt” is already having an impact on healthcare conversations. That’s the finding from a new study released Monday by the USC Norman Lear Center, which said “The Pitt” has shifted the conversation on issues such as organ donation and end-of-life planning. According to a group of 1,409 viewers […]

variety.com

A landmark moment for palliative care research! Discover the long journey that led to this breakthrough and why it matters for patients and clinicians. Read the full blog here: https://ow.ly/k31F50XkpUv

A Long Road to a Landmark Moment in Palliative Care Research | AAHPM

Kyle P. Edmonds, MD FAAHPM Clinical Professor at UC San Diego Health Sciences Health Policy Strategic Coordinating Commitee Chair When I first walked the halls of Capitol Hill in 2013 […]

ow.ly

Interesting🤔

How do vaccines reduce the risk of dementia? | University of Oxford

A new study by the University of Oxford, published in the journal npj Vaccines, shows that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk in

ox.ac.uk

Robotic surgery outperforms laparoscopic in rectal cancer. Next step: train robots using AI like that in self-driving cars and humanoids. How long before an AI-driven robot beats the surgeon-controlled one?

JAMA@jama.com · last yr.

Robotic surgery for middle or low rectal cancer demonstrated lower 3-year locoregional recurrence rates and improved functional outcomes compared to conventional laparoscopic surgery. #ASCO25 https://ja.ma/4mGtyBh

Excess death in US compared to other high-income countries. This trend can probably only be broken by the Ozempic-pandemic🤔 and maybe some sensible healthcare reforms💡.

Excess US Deaths Before, During, and After the COVID-19 Pandemic

This cohort study examines trends in excess deaths in the US before, during, and after the COVID-19 pandemic.

jamanetwork.com

Superhuman performance of a large language model on the reasoning tasks of a physician. arxiv.org/abs/2412.10849

Hospitalized patients with dementia are infrequently present in GOC conversations and less likely to have their values and preferences for medical care documented within a GOC note. #geriatrics #palliativecare agsjournals.onlinelibrary.wiley.com/doi/10.1111/...

Human(?) development is about to jump to hyperspace. With small tweaks, this could be applied to everything from scientific research to factory floors and logistics.

DeepMind unveils ‘spectacular’ general-purpose science AI

System improves chip designs and tackles unsolved maths problems, but has not been rolled out to researchers outside the company.

nature.com

“Our study demonstrated associations between obesity, particularly severe obesity, and the incidence of 16 common health outcomes.” 📋 Read the full study results by Z. Yao et al. in NEJM Evidence: eviden.cc/4iIRjGg #MedSky #EndoSky

Heart and Kidney disease are related. Many patients have both, leading to CKM syndrome. http://spr.ly/6048uP0fo As many as 9 in 10 adults with CKD don't know they have it. Kidney disease usually has 0 symptoms, & many people don’t know they have it until it’s very advanced.

Symptom support, unbiased and pure. Taking on the toughest cases: elderly patients. Get diagnoses and suggested investigations. Powered by our own AI (not Big Tech), but we use LLM as a sidekick. Easy, no login, free to use: Oired.com

In the API-CAT trial involving patients with active cancer and venous thromboembolism, extended anticoagulation with reduced-dose apixaban was noninferior to full-dose apixaban for preventing recurrent thromboembolic events. Full trial results and Research Summary: nej.md/41YkRZK #MedSky

In Type 2 Diabetes SLGT2 decreased risk of Alzheimer with 43% and GLP-1 with 33% compared with other DM2 medications. No significant difference between SLGT2 and GLP-1. jamanetwork.com/journals/jam...

Read, learn, think and challenge yourself should be added throughout life.

Ian Kremer@wolverinebear.bsky.social · last yr.

Help Reduce Your Risks of #Dementia #Alzheimers #health #publichealth

Zoster vaccine reduced the probability of a new dementia diagnosis by approximately 20% over a seven-year follow-up period.

”On average, each dollar spent on vaccination yields a hefty $54 in returns.” - That is a good investment!

First, jab more babies

As aid shrinks, donors and recipients should focus more on health

economist.com

NEJM: Global Effect of Cardiovascular Risk Factors on Lifetime Estimates. With all 5 risk factors (high blood pressure, high cholesterol, diabetes, smoking, and unhealthy body weight) at age 50 lifetime cardiovascular disease risk was 38% in men and 24% in women. www.nejm.org/doi/full/10....

Treating coronary artery disease risk factors early could make it a rare disease. But are we ready to take pills to prevent a disease that might occur 40 years later? Of course, a middle way already exists in clinical practice. However, this Lancet Commission rightly highlights prevention.

The Lancet@thelancet.com · 2y ago

🆕 Coronary artery disease (CAD) remains a leading cause of global morbidity & mortality. A Lancet Commission redefines CAD, emphasising early detection, risk factor management, & a comprehensive approach to prevention throughout the life course: tinyurl.com/5axhtr85 #ACC25 #MedSky

About to retire, prepare yourself or risk cognitive decline.

Retirement Can Harm Your Brain. Here’s How to Keep It Healthy.

It’s challenging to stay mentally sharp and healthy through the major transition. Careful planning is key.

nytimes.com

The number of geriatricians is shrinking, just 7,400 in 2022, down from 10,000 in 2000, while the aging population keeps growing. The American Geriatrics Society says we’ll need 30,000 by 2030. The math isn’t adding up!

America's aging population faces a growing shortage of geriatric care

For a variety of reasons, geriatric care experts told BI it's been hard attracting new doctors to the field. It's a problem for an aging US population.

businessinsider.com

A pie graph worth keeping in mind as the NIH budget plummets jamanetwork.com/journals/jam... for 356 new FDA drugs approved

#Kindness cannot prevent, slow or cure #Alzheimers. But the presence or absence of kindness fundamentally changes quality of life for people experiencing #dementia and those who are #caregiving. #quote

Gene repair inside the human body is now a reality.

Science Magazine@science.org · 2y ago

For the first time, researchers have used the #CRISPR gene editor to repair a flawed gene in the human body. scim.ag/3RdMzMT

Updated.

This aligns with the clinical picture and not just for dementia: a 75-year-old today is in the same shape as a 65-year-old 30–40 years ago. Possible reasons: Less smoking? Less physical labor? Fewer severe infections (vaccination/antibiotics)? Cholesterol-lowering drugs? Less pollution? …

JAMA@jama.com · 2y ago

Viewpoint: Despite the expected increase in dementia due to an aging population, age-specific dementia prevalence rates in the US have declined by approximately two-thirds from 1984 to 2024. https://ja.ma/4hyAmNA

Digital screen time and myopia risk: Under 1 hour/day relatively safe, but risk increases 21% for each extra hour.. 👓 jamanetwork.com/journals/jam...