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Olaya Rendueles

@olayarendueles.bsky.social

Microbial evolution & ecology, focus on surface structures (capsules) and HGT (#plasmids #phages), mostly in #Klebsiella #MicroSky From #Asturias 🇪🇸 living in 🇫🇷 @CNRS

234 Posts2003 Follower697 Folgt
Olaya Rendueles@olayarendueles.bsky.social · 4w ago

There are few threads left to hold everything together in #Spain, and soccer is one of them. Tomorrow, all seams will burst open. But today,at least today,let’s enjoy and just be happy for a while. #WorldCup And #Trump has the nerve to say that we don’t invest in defense in Spain 🤣 VAMOOOOS 🇪🇸 !

Olaya Rendueles@olayarendueles.bsky.social · 3mo ago

🔬🦠 Comment #Klebsiella parvient-elle à changer de capsule aussi fréquemment pour mieux s’adapter à son environnement ? Les travaux de @julielebris.bsky.social mis à la une par @cnrsbiologie.bsky.social 👏 -avec @epcrocha.bsky.social #MicroSky @cbitoulouse.bsky.social

CNRS Biologie@cnrsbiologie.bsky.social · 3mo ago

#ResultatScientifique🔎| Une bactérie capable de changer de « bouclier » pour mieux s’adapter à son environnement : une stratégie étonnante de Klebsiella pneumoniae qui éclaire ses capacités d’évolution et de résistance. ✍️ @olayarendueles.bsky.social @julielebris.bsky.social ▶️ buff.ly/q8AKHo1

Prof. Ruth Ley FRS@microbiome.bsky.social · 4mo ago

Come and work with us in a beautiful corner of Germany: 5 years of funding for your microbiology research and lots of great colleagues 🦠🧫

Andreas Peschel @andreaspeschel.bsky.social · 4mo ago

You are an ambitious young scientist, on the verge to independence, in a research field related to our Cluster of Excellence @cmfi.bsky.social “Controlling Microbes to Fight Infections”? Join our vibrant, interactive scientific community in Tubingen. Repost and apply! www.nature.com/naturecareer...

Klebsiella Club@klebclub.bsky.social · 4mo ago

TODAY!! Join us for Session 3 of #KlebClub2026 📅 April 23rd ⏰ 9:00–10:30 AM EDT 🔬 Theme: Translational Microbiology Hear from researchers bridging bench to bedside and explore innovative approaches to tackling Klebsiella pneumoniae. ✨ Free registration ->scan the QR code on poster

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Fernando Gonzalez-Candelas @fgonzalef.bsky.social · 4mo ago

We are hiring a PhD candidate! Only for non-EU graduates. To work on the molecular and genomic epidemiology of Treponema pallidum, based on our recent publication (doi:10.1128/mbio.00358-26). Interested? Send your CV and an expression of interest to fernando.gonzalez@uv.es before May 20th, 2026.

uv.es

Daniel Padfield@padpadpadpad.bsky.social · 5mo ago

PLEASE SHARE. PhD Opportunity with me, Ben Raymond and Jan Engelstaedter and Andrew Letten at University of Queensland. Experimentally testing mechanisms of how temperature may change selection and spread of AMR in E. coli. Coupled with some advanced modelling and sequencing. 🧪🦠 #microsky

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Olaya Rendueles@olayarendueles.bsky.social · 5mo ago

Our latest manuscript explores capsule exchangeability & phenotypic portability We didn’t directly address its role in #virulence ⏩️ that was already elegantly shown here—worth a look 👀👇🏻 doi.org/10.1371/jour... 🎯 Their results supports our plug-and-play model! Bonus: we kept 🐭 alive #microsky

Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver

Author summary Klebsiella pneumoniae is a major human pathogen. While capsule is the main virulence factor of the pathogen, only several of more than 80 capsule serotypes are frequently identified in ...

doi.org

PLOS Biology@plosbiology.org · 5mo ago

How do multi-gene systems evolve across genetic backgrounds without disruptive epistasis? @julielebris.bsky.social @olayarendueles.bsky.social &co show the #Klebsiella capsule locus is a plug&play module that swaps with low fitness cost while preserving #virulence @plosbiology.org 🧪 plos.io/4s64Ko0

Characteristics and capsule production of capsule-swapped strains. Genetic (lower triangle) and biochemical (upper triangle) relatedness between the different capsule types analyzed in this study. Biochemical similarity was calculated as the percentage of residues shared between two K types (# of shared unique oligosaccharides/# of different nonredundant oligosaccharides). Oligosaccharidic compositions and models were taken from K-PAM. Genetic relatedness was calculated taking into account all homologous genes between two K types. Monosaccharides composing the different capsules are depicted according to the Symbol Nomenclature for Glycans convention.
Olaya Rendueles@olayarendueles.bsky.social · 5mo ago

So happy to see this finally published in @plosbiology.org! This is the first chapter of @julielebris.bsky.social PhD thesis demonstrating how capsules are exchanged by plug-and-play dynamics w/ @epcrocha.bsky.social #microsky @klebclub.bsky.social Link below- Check out her 🧵 for more details!

Plug-and-play evolution of the Klebsiella pneumoniae capsule locus enables serotype exchange across genetic backgrounds

How complex multi-gene systems evolve across genetic backgrounds without disruptive epistasis remains unclear, particularly in highly exchangeable loci such as the capsule of Klebsiella pneumoniae. Th...

doi.org

Julie Le Bris@julielebris.bsky.social · 11mo ago

How complex functions, with important physiological and evolutionary impacts get repeatedly and efficiently transferred across genomes? That’s what we explored using one of the fastest-evolving loci in Bacteria: the capsule locus. The paper: www.biorxiv.org/content/10.1... Thread👇

Microbiology Society@microbiologysociety.org · 6mo ago

#OnThisDay in 1938, American evolutionary biologist Lynn Margulis was born. Margulis is most known for developing and popularising the endosymbiotic theory, which explains how eukaryotic cells evolved organelles from simpler prokaryotic organisms that resided within another and became incorporated.

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