Owen Ouyang

@owenouyang.bsky.social

Graduate student at the University of Illinois. I like antibodies, national parks and running:) I'm also an eLife community ambassador! @elifecommunity.bsky.social

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I'm thrilled to share that the oPool⁺ display is on the cover of this week's #ScienceTranslationalMedicine! We hope that the future use of this platform can accelerate antibody characterization, benefit therapeutic & vaccine development, and facilitate iterative refinements of antibody AI models.

Science Magazine@science.org · last yr.

Don't miss the new issue of #ScienceTranslationalMedicine! A clinical study in Nepal shows that waning immunity to Japanese encephalitis virus can worse the severity of dengue, a new platform leapfrogs laborious obstacles in antibody discovery, and more. https://scim.ag/47qcFpw

The cover shows a library of antibody single-chain variable fragment (scFv)-mRNA-cDNA fusion molecules targeting an influenza hemagglutinin immobilized on a magnetic bead surface.

Academia is built on collaboration and mentorship. However, as ECRs, we tend to hesitate to reach out to our seniors. In our latest ecrLife post, @owenouyang.bsky.social encourages young scientists to give it a try, since many seniors are happy to write back and provide advice. tinyurl.com/35u7hw5h

Reaching Out to Senior Scientists: A Step Worth Taking

When we start out as early career researchers, we often hesitate to reach out to senior scientists. However, they are often excited to help young scientists. Here, Owen Ouyang discusses how mentorship...

ecrlife.org

In this updated manuscript, now available on bioRxiv, we are excited to (re)introduce oPool+ display, a high-throughput cell-free platform that enables rapid synthesis and specificity characterization of natively paired antibodies at an unprecedented scale: www.biorxiv.org/content/10.1... (1/)

High-throughput synthesis and specificity characterization of natively paired antibodies using oPool+ display

Antibody discovery is crucial for developing therapeutics and vaccines as well as understanding adaptive immunity. However, the lack of approaches to synthesize antibodies with defined sequences in a ...

biorxiv.org