Mini-reunion of @costalaboratory.bsky.social from the 2020/21 era. Had a great time at the 94th Harden Conference in Crete, reconnecting with old colleagues and making new connections. Looking forward to the next one! @biochemsoc.bsky.social @tcr-miller.bsky.social @puehringertom.bsky.social

New preprint from our lab! We've been working out how the CMG replicative helicase gets built. 🧵 1/3

New preprint! How does Mcm10 promote the establishment of two divergent replication forks from one MCM double hexamer? Our @giacomopalm.bsky.social found the answer. 🧵 1/3

Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳 Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m

Had a great time at 3R+3C in Fukuoka, Japan representing @costalaboratory.bsky.social. Great to hear about some amazing science and experience Japan! Until next time at 3R+3C+D! And congrats to @puehringertom.bsky.social for winning a poster prize - well deserved!