🚨 Postdoc position open! Join us at Umeå University to study proteins that maintain mitochondrial DNA stability. 2-year fellowship | International research environment | Apply now! 🔗 umustipendie.varbi.com/en/what:job/... #Postdoc #Mitochondria #Biochemistry #AcademicJobs

Postdoctoral fellowship (2 years) to study proteins that maintain mitochondrial DNA

The Department of Medical Biochemistry and Biophysics is offering a postdoctoral scholarship within the project "Signaling of mitochondrial DNA instability". The scholarship is full-time for two year

umustipendie.varbi.com

Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. Read more: academic.oup.com/nar/article-...

The low endoribonuclease activity and lack of rNMP preference of human mitochondrial topoisomerase 1 protect against ribonucleotide-dependent deletions

Abstract. The incorporation of ribonucleotides (rNMPs) into the nuclear genome leads to severe genomic instability, including strand breaks and short 2–5 b

academic.oup.com

Only just over a week left to apply for a postdoc position in our lab - if you are passionate about mtDNA maintenance and biochemistry or signaling, here is your chance!

Paulina Wanrooij@paulinawanrooij.bsky.social · last yr.

Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share! www.umu.se/en/work-with...

Two mtDNA papers of ours in one PNAS issue: #1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund #2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab www.pnas.org/toc/pnas/122...

Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share! www.umu.se/en/work-with...

Postdoctoral fellowship (2 years) to study mitochondrial DNA stability

umu.se

Our newest paper on mtDNA instability signaling by Gustavo Carvalho, Tran Nguyen and Bruno Repolês et al is out: Activating AMPK improves pathological phenotypes due to mtDNA depletion - Carvalho - The FEBS Journal - Wiley Online Library febs.onlinelibrary.wiley.com/doi/full/10....

FEBS Press

In a cellular model of mitochondrial disease characterized by progressive mitochondrial DNA (mtDNA) depletion, we found that advancing mitochondrial dysfunction triggers the early and specific activa...

febs.onlinelibrary.wiley.com

We are hiring! We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level. Review the details below👇or visit borjaibarralab.com 💻