Here’s the last major paper from the PhD of @paulknabl.bsky.social. We were trying to understand what BMP signaling does in the sea anemone Nematostella when it is not patterning its second body axis. Check out Part 1 in BMC Biol. 2025; and here's is our Part 2 journals.plos.org/plosbiology/...

The anti-neural role of BMP signaling is a consequence of its ancestral function in dorsoventral patterning

Bilaterian animals with centralized nervous systems have patterns of BMP signaling activity gradient that suggest an “anti-neural” ancestral role, but the evidence for this remains unclear. This study...

journals.plos.org

Bilaterian BMP signaling gradients suggest an ancestral anti-neural role. Study of #cnidarians shows that #BMP signalling promotes neurogenesis; its "anti-neural" function is a side effect of its role in the DV axis @paulknabl.bsky.social @genikhovich.bsky.social @plosbiology.org 🧪 plos.io/4dJHoiR

Congrats to Nadja and the @tessmarraiblelabs.bsky.social. Check out their cool new work (featuring a small sketch I made)!

Tessmar-Raible Labs@tessmarraiblelabs.bsky.social · 8mo ago

Freshly out at @natcomms.nature.com ! Our @univie.ac.at @awi.de @viennabiocenter.bsky.social @ercgrantees.bsky.social research into neurogenic plasticity of adult worm brains, and similarities in stem cells supporting growth of camera-type eyes. www.nature.com/articles/s41... [1/7]

David’s @davidmoersdorf.bsky.social cool paper about the role of Chordin in BMP signaling in the sea anemone Nematostella is finally out www.science.org/doi/10.1126/...

Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian

Chordin-mediated BMP shuttling is the candidate mechanism for generating bilateral symmetry in the cnidarian-bilaterian ancestor.

science.org

The last part of @paulknabl.bsky.social 's PhD is now available at www.biorxiv.org/content/10.1... Paul showed that BMP signaling is active in the diffuse nervous system of the sea anemone Nematostella and the box jellyfish Tripedalia. Moreover, suppression of BMP signaling in Nematostella leads...

The anti-neural role of BMP signaling is a side effect of its global function in dorsoventral patterning

In Bilateria with centralized nervous systems (e.g. in vertebrates or arthropods), the minimum of the BMP signaling activity gradient defines the position of the central nervous system. BMP-dependent ...

biorxiv.org

Our atlas of BMP signaling activity in adult Nematostella is finally out! Fantastic, meticulous work and beautiful illustrations by @paulknabl.bsky.social Thanks, @fwf-at.bsky.social for funding our work! bmcbiol.biomedcentral.com/articles/10....

A whole-body atlas of BMP signaling activity in an adult sea anemone - BMC Biology

Background BMP signaling is responsible for the second body axis patterning in Bilateria and in the bilaterally symmetric members of the bilaterian sister clade Cnidaria—corals and sea anemones. Howev...

bmcbiol.biomedcentral.com

Big parts of my PhD work is now out on bioRxiv!! We look at how biophysical parameters shape the fractal lung during development and disease. Go check it out: www.biorxiv.org/content/10.1...

The emergence of the fractal bronchial tree

The fractal design of the bronchial tree, as described by the Hess-Murray law, facilitates energy-efficient lung ventilation, yet its developmental origins remain unclear. Here, we quantify the rearra...

biorxiv.org

Dagmar Iber & CoBi@iberd.bsky.social · 2y ago

How does an #embryo build an energy-efficient #fractal #lung in time for the first breath at birth? 🫁 Discover the mechanical forces shaping the bronchial tree in our latest preprint: #LungDevelopment #Mechanobiology doi.org/10.1101/2025... 👇Thread 🧵(1/9)

I recently got to illustrate the graphical abstract for this beautiful work on stem cells and regeneration in the #bristleworm by @alexwstockinger @leonieadelmann @tessmarraiblelabs.bsky.social Check it out!

Tessmar-Raible Labs@tessmarraiblelabs.bsky.social · 2y ago

Excited to dedicate our #FirstSkeet to our new #OpenAccess publication in Nature Communications revealing how #bristleworms make new #StemCells for #Regeneration of their body axis www.nature.com/articles/s41... ... (1/7)