Excited to share our new preprint offering a first glimpse into the cross-kingdom molecular dialogue between legumes and rhizobia! www.biorxiv.org/content/10.6...

A cross-kingdom interactome predicted by AlphaFold3 reveals a DNF2-centered interface required for symbiotic accommodation

Legumes convert atmospheric nitrogen into ammonium through symbiotic bacteria housed in root nodules, yet the molecular interactions between rhizobial and host proteins inside nodules remain poorly un...

biorxiv.org

Thrilled to share our latest insights into engineering nitrogen-fixing symbiosis! We sincerely appreciate the reviewers’ constructive comments and the editor’s kind guidance throughout the process. @cp-trendsmicrobiol.bsky.social

Trends in Microbiology@cp-trendsmicrobiol.bsky.social · last mo.

Engineering nitrogen-fixing symbiosis: bridging signaling and intracellular entry

Wanted: Outstanding plant scientist and fantastic colleague. If your science combines fundamental discovery with future applications, we would love to hear from you @dompsfr.bsky.social @biologyunifreiburg.bsky.social @cibss.bsky.social @uni-freiburg.de uni-freiburg.de/en/job/00005...

Excited to share our paper now online @theplantjournal.bsky.social. We reveal a nitrate-responsive regulatory network governing symbiotic nitrogen fixation in Medicago, identifying HHO3 as a central regulator. A wonderful collaboration with Xue and Qingchuan. onlinelibrary.wiley.com/doi/10.1111/...

Identification of symbiotic nitrogen fixation‐modulating factors in alfalfa and mechanism elucidation of MsHHO3

HHO3 acts as a key regulator of nitrate-responsive SNF by directly targeting several intermediate hormone-related TF-encoding genes (MsMYC2, MsRAV1, MsbHLH18, MsMYB108, MsMYB11) to initiate a transcr...

onlinelibrary.wiley.com

What a beautiful journey! Huge thanks to all the amazing collaborators who made this work possible.

Thomas Ott@ottlab.bsky.social · 7mo ago

Happy to share our latest work in collaboration with the lab of @pengbo10.bsky.social. Here, we describe that a formin protein mediates the polarity switch from root hair to infection thread growth during symbiotic interactions. www.science.org/doi/10.1126/...

Congrats @ottlab.bsky.social and @pengbo10.bsky.social for leading this work!

ENSA - Enabling Nutrient Symbioses in Agriculture@ensa-research.bsky.social · 7mo ago

🔬 ENSA research uncovers SYFO2, a molecular gatekeeper that reorganizes actin in legume root hairs to allow rhizobial entry. The team showed that tomato can activate its own SYFO2 pathway, revealing deep evolutionary roots of symbiosis @science.org @ottlab.bsky.social @pierremarcdelaux.bsky.social

What an honor to have Nobel Laureate Mario Capecchi give an special lecture at China Agricultural University! A truly inspiring encounter. #CAU #NobelLaureate

We’re thrilled to share our latest preprint! In this study we provide a mechanistic insight into how the protein EPP1 (first identified in Rose et al., 2012) functions in partnership with SYMRK. www.biorxiv.org/content/10.1...

EPP1 couples receptor activation to cytoplasmic signaling in root nodule symbiosis

Legume symbiosis with nitrogen-fixing bacteria is controlled by a cascade of signaling events leading to root nodule development. While plant cell-surface receptors initiate this process, the link bet...

biorxiv.org

So enlightening to have @tonnigrubeandersen.bsky.social to share brilliant insights on plant barriers today at CAU.