PM Delaux

@pierremarcdelaux.bsky.social

Biologist @lrsv-toulouse.bsky.social @cnrs.fr working on #symbiosis and #evolution @erc.europa.eu #ENSA_project #EMBO_YIP www.evolutionpmi.com/

Nice summary of our recent preprint on the lipid-based innovations that facilitated plant terrestrialization ! Comments are more than welcome!

preLights@prelights.bsky.social · 4d ago

Did one gene family help plants colonise land? Zamar et al. @pierremarcdelaux.bsky.social show how a land-plant-specific enzyme family, p-GPATs, is involved in two different processes: cuticle formation & arbuscular mycorrhizal symbiosis #preLight by Naveen⬇️ prelights.biologists.com/highlights/a...

Ça va continuer encore longtemps, le rassurisme sur les néonazis allemands, ou il faut encore trois quatre Länder pour que ça monte au cerveau des gens ?

Légère baisse des températures, les canicules et les 8000 morts (à ce stade) en excès sont un lointain souvenir, il est enfin temps pour le gouvernement de sabrer joyeusement dans les budgets de l'écologie, même si Bernard Arnault aussi, il a chaud.

J'adore Lecornu qui annonce une baisse de la taxation des héritages et de la contribution des entreprises financée par un deremboursement des soins médicaux.

Nature did a nice, accessible write up of a recent piece I wrote with @mjcrockett.bsky.social, Kevin Gross, and @carlbergstrom.com. Also, check out Carl's more detailed thread (with link to the paper in both). "Scientists using LLMs will ‘do more, less well'" www.nature.com/articles/d41...

Scientists using LLMs will ‘do more, less well’, modelling study predicts

Research suggests that the combination of incentives to publish and the use of large language models will lead to more papers, but they will be less refined.

nature.com

Carl T. Bergstrom@carlbergstrom.com · 2mo ago

1. We—@eduede.bsky.social, @mjcrockett.bsky.social, Kevin Gross, and I—have a new preprint on the arXiv today, based on ideas that emerged during an @sfiscience.bsky.social workshop in November 2024: The unintended consequences of large language models as a labor-augmenting technology in science.

For the record, "fewer larger grants" is the opposite of how to fund good research. Give a bunch of researchers financial stability and basic funding, without wasting their time on increasingly competitive applications and widening the have/have-not gap, and look how far we'll go.

Les ex-1er ministres voire Ministre de l'Education et candidats à la présidentielle qui poussent des cris d'orfraie à la lecture du classement PISA vous êtes conscients que c'est de votre bilan dont il s'agit ou il faut qu'on vous le rappelle ?

Latest paper from our lab in collaboration with Jason Wallace and Natalia de Leon -> Genetic determinants of aerial root morphology in Sierra Mixe-derived maize

Genetic determinants of aerial root morphology in Sierra Mixe-derived maize

Key Message We mapped key regions of the maize genome that influence the formation of aboveground (aerial) roots, which in some varieties have been associated with symbiosis with nitrogen-fixing bacteria. Abstract Modern agriculture relies heavily on chemically synthesized nitrogen fertilizers, which ensure high yields but also carry high economic and environmental costs. Biological nitrogen fixation (BNF) supplies high amounts of nitrogen to legumes, and several avenues of research are underway to extend it to cereal crops. In maize, aerial roots formed in Sierra Mixe landraces have been associated with BNF. However, much of the genetics underlying aerial root morphology remains unknown. Here, we evaluate aerial root morphology traits associated with BNF in three segregating populations derived from crosses between two Midwest-adapted inbred lines and three landraces. Inclusive composite interval mapping (iCIM) with flowering time as a covariate identified 37 quantitative trait loci (QTL) for three aerial root traits (nodes with roots, root size, and roots per node) which exhibit moderately high heritability (H2 = 0.65 to 0.83). The combined proportion of phenotypic variance explained by the detected QTL ranged from 23 to 51%, depending on the trait and population, and potential candidate genes were identified through literature searches, macrosynteny, and gene expression analyses. Introgressing the most relevant aerial root-associated QTL into elite genotypes may provide a path toward achieving meaningful levels of BNF-associated traits in maize, but further work is needed to assess this approach's viability under field conditions.

sco.lt

Our lab is looking for PhD students to join us in 2027 🎓🎉 The projects can be structured around our research directions: - Transposable element dynamics - Fungal pangenomics - ML/language model genomics applications - Pathogen adaptation More here pathogen-genomics.org ("Jobs") and please share! 🙏

Evolutionary genomics of pathogens

Croll lab at University of Neuchatel. The lab of Daniel Croll wants to understand how pathogens evolve to cause disease. For this, we mainly focus on major crop pathogens to unravel mechanisms of rapi...

pathogen-genomics.org

[⚠️JOB ALERT⚠️] We are looking for a Research assistant (IE for those familiar with the French system) in molecular biology to run DAPseq in the lab. 18 months contract (to start) Start date: October 1st. Exprience in library prep., in vitro transcription/translation system or DAPseq is a must.

Recent work from the lab. Even after hundreds of generations of intense directional selection at relatively small Ne, substantial genetic variation persists, and can be rapidly redeployed when the direction of selection reverses. Results are suggestive of balancing selection. doi.org/10.1093/molb...

Beyond Fixation: Persistent Genetic Variation Under Intense Selection

Abstract. Understanding how and why genetic variation is maintained under sustained selection remains a central question in evolutionary genetics. Experime

doi.org

Finally online! It took ut 9 yars from formulating the hypothesis to actually finalizing the last experiments... but there it is!

Mélanie Rich 🌱🍄@melaniekrich.bsky.social · 2mo ago

New preprint alert! www.biorxiv.org/content/10.6... The conclusion of a long-lasting obsession about lipids, plant terrestrialization and the origin of plant symbioses 1/7 🧵 @pierremarcdelaux.bsky.social @katharinamel1.bsky.social @tatiana-vernie.bsky.social @kellerjeanphd.bsky.social