Today at 12pm CT! Janet Sorrells, PhD presents the Monthly Seminar on Physical Genomics: Biochemical, Metabolic, And Structural Profiling Of The Tissue Microenvironment With Computationally Accelerated Multimodal Nonlinear Optical Microscopy" live on Zoom. Register here: tinyurl.com/3zhzu57j
@PhysGenCenter
@physgencenter.bsky.social
The mission of the Center for Physical Genomics and Engineering at Northwestern University’s McCormick School of Engineering is to create new strategies for the treatment of disease and the reversible manipulation of living systems
Tomorrow! The Monthly Seminar on Physical Genomics features Dr. Vasundhara Agrawal, CPGE alumnus and Applications Manager for Spatial Biology Image Analysis at Leica Microsystems, discussing her path from academia to industry. #northwestern #leica Registration is free at: tinyurl.com/2rw8n7bt
This Friday! The Monthly Seminar on Physical Genomics features Dr. Vasundhara Agrawal, CPGE alumnus and Applications Manager for Spatial Biology Image Analysis at Leica Microsystems, discussing her path from academia to industry. #northwestern #leica Registration is free at: tinyurl.com/2rw8n7bt
The June Seminar on Physical Genomics will feature Dr. Vasundhara Agrawal, CPGE alumnus and Applications Manager for Spatial Biology Image Analysis at Leica Microsystems Boston Innovation Hub, discussing her career path from academia to industry. Registration is free at: tinyurl.com/2rw8n7bt
Today's Seminar on Physical Genomics with Michael Shelley, PhD will be rescheduled due to illness. Notifications have been sent to all registrants - we will have a new date as soon as possible. Thank you!
Join us at 12pm CT tomorrow, May 29, as Michael Shelley PhD presents the Monthly Seminar on Physical Genomics: "Modeling Chromatin as an Active Polymer Melt". Registration is free but required at tinyurl.com/2rw8n7bt #chromatin #genomics #northwestern #polymer #physics #nyu #cpge #nih #nsf
CPGE in Biophysical Journal: "One Chromatin, Many Structures: From Ensemble Contact Maps to Single-Cell 3D Organization" SR-EV clarifies the probabilistic nature of genome architecture and provides a reference framework for interpreting multimodal genomic/imaging data www.cell.com/biophysj/ful...
One Chromatin, Many Structures: From Ensemble Contact Maps to Single-Cell 3D Organization
Understanding how chromatin folds in three dimensions remains challenging because most experimental assays capture low-dimensional projections of an underlying, highly heterogeneous polymer. Here we p...
cell.com
Join us on Zoom Friday May 29 @ 12pm CT as Michael Shelley, PhD presents the Monthly Seminar on Physical Genomics: "Modeling Chromatin as an Active Polymer Melt". Registration is free, but required at tinyurl.com/2rw8n7bt #chromatin #genomics #northwestern #polymer #physics #modeling #nyu
Last week's fantastic seminar by Prof. Harmit Malik, "Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins", can now be viewed on CPGE's YouTube channel! youtu.be/VxSppXrqGfI #chromatin #genomics #evolution #northwestern #genomics #proteins #dna #fredhutch
Harmit Malik- Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins
YouTube video by Center for Physical Genomics and Engineering
youtu.be
Next Friday April 24 @ 12pm CT, Dr. Harmit Malik presents the Monthly Seminar on Physical Genomics: "Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins", live on Zoom. Registration is free, but required at tinyurl.com/2rw8n7bt #chromatin #genomics #proteins #dna
New CPGE research published in JoVE presents a protocol that harnesses the intrinsic fluorescence of DNA to perform spectroscopic single-molecule localization microscopy (sSMLM). "Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast" app.jove.com/t/69917/spec...
app.jove.com
Prof. Javier Rodriguez-Casariego's fascinating seminar, "Epigenetic Mechanisms of Rapid Environmental Plasticity in Reef-Building Corals", is now available for viewing on the CPGE YouTube channel. Enjoy! #epigenetics #chromatin #genomics #corals #northwestern #reefs #science youtu.be/lcp9TyW8UTs
Javier Rodriguez-Casariego- Epigenetic Mechanism of Rapid Environment Plasticity Reef-Building Coral
YouTube video by Center for Physical Genomics and Engineering
youtu.be
Today @ 12pm CT! Dr. Javier Rodriguez-Casariego presents the Monthly Seminar on Physical Genomics: "Epigenetic Mechanisms Of Rapid Environmental Plasticity In Reef-Building Corals", live on Zoom. Join us! Registration is free, but required at tinyurl.com/2rw8n7bt #epigenetics #corals #genome
This Friday March 27 @ 12pm CT Dr. Javier Rodriguez-Casariego presents the Monthly Seminar on Physical Genomics: "Epigenetic Mechanisms Of Rapid Environmental Plasticity In Reef-Building Corals", live on Zoom. Registration is free, but required at tinyurl.com/2rw8n7bt #epigenetics #corals #genome
Join us Friday March 27 @ 12pm CT for the Monthly Seminar on Physical Genomics as Dr. Javier Rodriguez-Casariego presents "Epigenetic Mechanisms Of Rapid Environmental Plasticity In Reef-Building Corals" live on Zoom. Registration is free, but required at tinyurl.com/2rw8n7bt #epigenetics #corals
The fantastic February 2026 Seminar on Physical Genomics by Prof. Steve Henikoff can now be watched on CPGE's YouTube channel: "Histone Overexpression in Cancer" #cancer #genomics #chromatin #epigenetics #northwestern #fredhutch #dna #research #science #biology #CPGE youtu.be/03sBNh4pN24
Steve Henikoff- Histone Overexpression In Cancer
YouTube video by Center for Physical Genomics and Engineering
youtu.be
Today at 12pm CT, Prof. Steve Henikoff presents the Monthly Seminar on Physical Genomics: "Histone Overexpression In Cancer" live on Zoom. Join us! Registration is free at tinyurl.com/2rw8n7bt #northwestern #cancer #genomics #research #chromatin #dna #epigenetics #science #research
This Friday Feb. 27 at 12pm CT, Prof. Steve Henikoff presents the Monthly Seminar on Physical Genomics: "Histone Overexpression In Cancer" live on Zoom. Join us! Registration is free at tinyurl.com/2rw8n7bt #northwestern #cancer #genomics #research #chromatin #dna #epigenetics #science #fredhutch
Friday Feb. 27 at 12pm CT, Prof. Steve Henikoff presents the Monthly Seminar on Physical Genomics: "Histone Overexpression In Cancer" live on Zoom! Registration is free at tinyurl.com/2rw8n7bt #northwestern #cancer #genomics #research #chromatin #dna #science #biology #cpge #fredhutch #research
“We did not set out to directly kill cancer cells. We wanted to take away their superpower — their inherent ability to adapt, to change and to evade.” CPGE's latest cancer research featured in Northwestern Magazine #cancer #chromatin #genomics #cpge magazine.northwestern.edu/discovery/va...
Hacking Cancer’s Survival Code
Northwestern professor Vadim Backman, who teaches in the McCormick School of Engineering and the Feinberg School of Medicine, is director of the University’s Center for Physical Genomics and Engineeri...
magazine.northwestern.edu
New preprint from the Hernando lab! www.biorxiv.org/content/10.6... Combining 3D genome profiling and high resolution imaging we demonstrate how chromatin architecture cooperate with mechanical confinement in conferring melanoma mesenchymal cells high migratory capacities.
biorxiv.org
Now on YouTube! Prof. Taekjip Ha's fantastic recent seminar at CPGE, "DNA Mechanics And Nucleosome Condensability As Biophysical Backdrop Of Genome Functions" #biophysics #chromatin #dna #northwestern #epigenetics #genomics #genome #science #harvard #CPGE youtu.be/G4I2dKr-dVE
Taekjip Ha- DNA Mechanics And Nucleosome Condensability As Biophysical Backdrop Of Genome Functions
YouTube video by Center for Physical Genomics and Engineering
youtu.be
Today at 12pm CT! The Monthly Seminar on Physical Genomics featuring Taekjip Ha, PhD of Harvard Medical School: "DNA Mechanics And Nucleosome Condensability As Biophysical Backdrop Of Genome Functions" Register for free at: tinyurl.com/3zhzu57j #genomics #chromatin #dna #biophysics #biology
Tomorrow at 12pm CT! The Monthly Seminar on Physical Genomics featuring Taekjip Ha, PhD of Harvard Medical School: "DNA Mechanics And Nucleosome Condensability As Biophysical Backdrop Of Genome Functions" Register for free at: tinyurl.com/3zhzu57j #genomics #chromatin #dna #biophysics #biology
Join us Friday, Jan. 30 at 12pm CT for the Monthly Seminar on Physical Genomics featuring Taekjip Ha, PhD of Harvard Medical School: "DNA Mechanics And Nucleosome Condensability As Biophysical Backdrop Of Genome Functions" Register for free at: tinyurl.com/3zhzu57j #genomics #chromatin #dna #gene
Today's fantastic seminar by Prof. Wendy Bickmore, "Chromatin Folding And Gene Activation: From The Nucleosome To Transcription Hubs", can now be viewed on the CPGE YouTube channel at youtu.be/6KLj9ThLL_U #chromatin #genomics #transcription #northwestern #cpge #dna #epigenetics #science #research
Chromatin Folding And Gene Activation: From The Nucleosome To Transcription Hubs
YouTube video by Center for Physical Genomics and Engineering
youtu.be
Today at 12pm CT, Wendy Bickmore, PhD presents the Monthly Seminar on Physical Genomics live on Zoom: "Chromatin Folding And Gene Activation: From The Nucleosome To Transcription Hubs" Registration is free. Join us! tinyurl.com/f9njvnyu #chromatin #genomics #genes #biology #dna #transcription
Friday, Nov. 21 @ 12pm CT, Wendy Bickmore, PhD presents the Monthly Seminar on Physical Genomics live on Zoom: "Chromatin Folding And Gene Activation: From The Nucleosome To Transcription Hubs" Registration is free. Join us! tinyurl.com/f9njvnyu #chromatin #genomics #northwestern #biology #dna
Friday, Nov. 21 @ 12pm CT, Wendy Bickmore, PhD presents the Monthly Seminar on Physical Genomics live on Zoom: "Chromatin Folding And Gene Activation: From The Nucleosome To Transcription Hubs" Registration is free. Join us! tinyurl.com/f9njvnyu #chromatin #genomics #northwestern #biology #dna
Think we've got DNA all figured out? Nope. Researchers at Northwestern University say our genome has a geometric code, and we may be "living, breathing computational systems." 😲 H/T @kylemacquarrie.bsky.social @physgencenter.bsky.social @nuintmed.bsky.social kimbellard.medium.com/life-is-geom...
Life Is Geometry
In 2025, we’ve got DNA all figured out, right? It’s been over fifty years since Crick and Watson (and Franklin) discovered the double helix…
kimbellard.medium.com