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Mariana Pinho

@pinholab.bsky.social

Full Professor at ITQB NOVA. Microbiologist. Microscopist. Bacterial Cell Biologist. Mother of 3.

21 Posts842 Follower173 Folgt
Mariana Pinho@pinholab.bsky.social · last yr.

Check out this tour de force by Nils Meiresonne and colleagues, establishing FLIM-FRET as a reliable way to study protein interactions in live bacteria with spatiotemporal resolution! We open the door to exploring divisome protein interactions during cell division. www.biorxiv.org/content/10.1...

FtsW protein-protein interactions visualized in live Staphylococcus aureus cells by FLIM-FRET

The bacterial cell cycle relies on the coordinated and dynamic interactions between division proteins and those involved in peptidoglycan (PG) synthesis. However, visualizing these interactions in viv...

biorxiv.org

Ricardo Henriques@henriqueslab.bsky.social · last yr.

Why do lower-resolution images sometimes yield better results in deep learning for bioimaging analyses? 🤔📉 Mariana Ferreira's new preprint on #ReScale4DL explores this paradox and introduces optimal resolution design! @gomez-mariscal.bsky.social brainchild🧑‍🔬✨ Check: www.biorxiv.org/content/10.1...

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Estibaliz Gómez de Mariscal, PhD@gomez-mariscal.bsky.social · last yr.

Yay! Mariana Ferreira submitted!🙌🥳 ⚖️📐📸📊🔬

Mariana Pinho@pinholab.bsky.social · 2y ago

All you wanted to know about chromosome segregation in Staphylococcus aureus and were afraid to ask - check our new preprint! A great collaboration with Xindan Wang´s lab! www.biorxiv.org/content/10.1...

Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus

Research on chromosome organization and cell cycle progression in spherical bacteria, particularly Staphylococcus aureus, remains limited and fragmented. In this study, we established a working model ...

biorxiv.org

@davidroper2.bsky.social · 2y ago

Please repost!!!!! Abstraction submission for the next Great Wall Symposium is now open! Come to Sicily in September and learn the latest on bacterial cell wall biology. thegreatwall-symposium.org/abstract-sub...

Pre-registration and Abstract Submission - The Greatwall-symposium

Registration and abstract submission open on January 15th, 2025.The organizers will select the final list of participants based on abstract submission, particularly for young scientist, and the applic...

thegreatwall-symposium.org

Itai Yanai@itaiyanai.bsky.social · 2y ago

Can't wait for this new meeting on drug resistance and tolerance across species and diseases. A principle revealed in one system – maybe using different terminology – could be the big new idea when imported to another! Abstract deadline in January! s.embl.org/ees25-01 @EMBO/@embl.org

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Mariana Pinho@pinholab.bsky.social · 3y ago

Super nice work from Simon Schäper showing that septal peptidoglycan synthases in S. aureus are not driven by FtsZ treadmilling. Instead they follow a one track model and their processive movement is dependent on peptidoglycan synthesis. www.nature.com/articles/s41...

Cell constriction requires processive septal peptidoglycan synthase movement independent of FtsZ treadmilling in Staphylococcus aureus - Nature Microbiology

Single-molecule imaging reveals that peptidoglycan synthesis and synthase activity, rather than FtsZ treadmilling, are rate limiting and drive septum constriction in Staphylococcus aureus.

nature.com