Jobs: My fantastic membrane biologist colleague Satyajit Mayor (warwick.ac.uk/fac/sci/med/...) has a really exciting single molecule #biophysics PDRA position currently advertised based at @warwickmed.bsky.social warwick-careers.tal.net/vx/lang-en-G...

Fantastic opportunity to join a brilliant lab and wider collaborative team!

Georgia Isom@georgiaisom.bsky.social · 4w ago

Interested in joining our group in Oxford? We are looking for a PDRA with single particle Cryo-EM experience to help us figure out how sphingolipids are transported to the cell surface of Gram-negative bacteria. The deadline is 31st July. Informal enquires are welcome. Please share!

🔥Kind of a big advance in CryoEM - www.science.org/doi/10.1126/...

Laser phase plate improves structure determination of small proteins by cryo-EM

Phase plates can in principle overcome the poor image contrast in electron cryo–microscopy (cryo-EM) and the resulting limits on the structural reconstruction of small proteins. However, previous desi...

science.org

Hey #MicroSky, can anyone tell me offhand whether Klebsiella pneumoniae ATCC13883 has rough or smooth LPS please? My searches are failing. Thank you :)

Banker-type hippocampal neuron culture world championship

Erik Hane@erikhane.bsky.social · 2mo ago

Okay but What would YOUR totally gratuitous White House lawn event be, if YOU were the mad king of a dying superpower

Update on GeneFrame alternative for bacterial imaging. After discussion with us and others, SunJin lab have how launched a substitute for timelapse imaging in geneframes www.sunjinlab.com/product/ispa... Dimensions are very similar, price is reasonable ($105 for 250) #microsky

Séamus Holden 🔬🦠🧫@seamusholden.bsky.social · last yr.

Fellow bacterial cell biologists, message me if you use @thermofishersci.bsky.social Gene Frames for microscopy! Thermo are planning to discontinue these in September but have indicated they will look into this further. If I make list of labs using them Thermo might not kill the product Please RT🔬🦠

Still some time to apply for this faculty position at Warwick!

Séamus Holden 🔬🦠🧫@seamusholden.bsky.social · 4mo ago

Join us! We are recruiting an Associate/ Assistant Professor in quantitative, systems and engineering biology (QSEB) @warwicklifesci.bsky.social . warwick-careers.tal.net/vx/lang-en-G...

Just over a week left to apply for this #PhD #studentship on S-layers and #AMR! Please share and if you want to know more, get in touch!

Prof Paula Salgado@pssalgado.bsky.social · 3mo ago

🧫 #AMR #PhD open @newcastleuni.bsky.social! How does #Cdifficile protein "armour" help it resist antimicrobials? Join me and @henrikstrahl.bsky.social to find out using: 🔬 #Structuralbiology, #microbiology #microscopy #genetics 📅 Deadline 20 May 2026 #PhD #PhDLife Pls share! (UK home only)

🤔 Still wondering how smFRET works in practice - and how it complements your current techniques? Our handbook shows when and why to use it alongside existing methods to add dynamic, single-molecule insight. Download: buff.ly/CxuqL1A #smFRET #biophysics #biochemistry

🧫 #AMR #PhD open @newcastleuni.bsky.social! How does #Cdifficile protein "armour" help it resist antimicrobials? Join me and @henrikstrahl.bsky.social to find out using: 🔬 #Structuralbiology, #microbiology #microscopy #genetics 📅 Deadline 20 May 2026 #PhD #PhDLife Pls share! (UK home only)

C. difficile S-layer’s role in antimicrobial resistance at Newcastle University on FindAPhD.com

PhD Project - C. difficile S-layer’s role in antimicrobial resistance at Newcastle University, listed on FindAPhD.com

findaphd.com

There's more - we also have a broad call for 6 Assistant Professors in @warwicklifesci.bsky.social www.nature.com/naturecareer...

Assistant Professor x6 - Coventry, West Midlands (GB) job with The University of Warwick | 12858563

The School of Life Sciences (SLS) wishes to appoint six excellent and ambitious early career principal investigators

nature.com

Join us! We are recruiting an Associate/ Assistant Professor in quantitative, systems and engineering biology (QSEB) @warwicklifesci.bsky.social . warwick-careers.tal.net/vx/lang-en-G...

A review on Super-resolution Structured Illumination Microscopy (SIM) to study endocytosis: pubs.acs.org/doi/10.1021/... Featuring our live-cell SIM of proximal axons showing frozen clathrin-coated pits within clearing of the spectrin mesh (doi.org/10.1126/scie...)

1) The Herzik lab is excited to announce our newest preprint in collaboration with the Grotjahn lab! We have developed a surfactant cocktail that seeks to overcome one of the more nefarious problems in #cryoEM, Air-water interface (AWI)-induced damage and preferred orientation (PO).

Neat paper from Schwille lab. They demonstrate constriction of synthetic vesicles using important components of the bacterial cell division machinery, FtsZ and FtsN. They induce strong constriction of Z-rings in vesicles just by adding the cytoplasmic domain of FtsN www.nature.com/articles/s41...

Optimizing spatial organization of FtsZ rings for large-scale constriction in synthetic cells - Nature Communications

Spatially regulated membrane constriction is an important milestone in reconstituting minimal cell division. Here the authors engineer a truncated system where the cytosolic domain of FtsN forms large...

nature.com

3D-MINSTED nanoscopy and protein tracking in densely labelled living cells https://www.biorxiv.org/content/10.64898/2026.03.09.710616v1

Come work with us in Oxford! www.jobs.ac.uk/job/DQL601/p...

Postdoctoral Research Associates in the Molecular Analysis of Bacterial Outer Membrane Biogenesis at University of Oxford

An opportunity for an academic position as a Postdoctoral Research Associates in the Molecular Analysis of Bacterial Outer Membrane Biogenesis is available, as advertised on jobs.ac.uk. Apply now and ...

jobs.ac.uk

Syma Khalid@sykhalid.bsky.social · 5mo ago

Come work with Ben Berks FRS in Oxford 2 x PDRA posts: Molecular Analysis of Bacterial Outer Membrane Protein Biogenesis 2 complementary projects investigating bacterial outer membrane protein biogenesis. Building on our recent work (Nature (2015) 647: 479-487) my.corehr.com/pls/uoxrecru...

There's still time to apply for this PhD position!

Séamus Holden 🔬🦠🧫@seamusholden.bsky.social · 6mo ago

iCASE PhD project available in my lab, combining microscopy method development with high throughput screening of bacteria. Applications to antibiotic drug discovery and screening for new cell division proteins. Collaboration with Cairn Research #microsky #bioimaging www.findaphd.com/phds/project...

During her PhD, Jenny found something unexpected: biofilm-deficient P. aeruginosa mutants were just as tolerant to antibiotics as the WT when grown in our cystic fibrosis lung model. But why? #MicroSky 1/n

This is a nice one! Congratulations @carballido-lab.bsky.social et al! Nice to see you agree that this might lead to local enrichment of cell wall precursor lipids. Not easy to prove but I still think its an attractive model (to ensure high CW synthesis given low lipid II levels).

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 6mo ago

ATP-driven membrane binding and polymerization of bacterial actin MreB promotes local membrane fluidization https://www.biorxiv.org/content/10.64898/2026.02.13.705564v1

The demand for #ProkaryoticCellBio so far has been crazy! We received a record number of abstract & grant submissions, to which the conference chairs are busy reviewing! We predict poster slots & accommodation to begin filling up, don't wait until the deadline to register! More info ➡️ bit.ly/4raYCu

Preprint on the permeability of Gram+ bacterial cell wall from a few months ago. Intriguing findings, elegant methodology. Cell wall is largely impermeable to molecule sizes of mNeonGreen (27kDa) and above. How do larger secreted proteins get through? www.biorxiv.org/content/10.1... #microsky

A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends. www.jbc.org/article/S002...

Bacteriocin biophysics: From protein-protein interaction models to navigators of the bacterial cell envelope

Bacteriocins are toxins deployed by bacteria to kill their competitors. Here, I reflect on my laboratory’s work on protein bacteriocins and their immunity proteins from Gram-negative bacteria. We unco...

jbc.org

iCASE PhD project available in my lab, combining microscopy method development with high throughput screening of bacteria. Applications to antibiotic drug discovery and screening for new cell division proteins. Collaboration with Cairn Research #microsky #bioimaging www.findaphd.com/phds/project...

Image-based bacterial phenotyping and antimicrobial drug discovery using smart high-throughput super-resolution microscopy at University of Warwick on FindAPhD.com

PhD Project - Image-based bacterial phenotyping and antimicrobial drug discovery using smart high-throughput super-resolution microscopy at University of Warwick, listed on FindAPhD.com

findaphd.com

Finally comms from UKRI - on a Sunday evening. No mention of the hundreds of ECRs who will see their careers ended by these decisions and notably no explanation for MRC retrospectively applying cuts and wasting all the work that went into writing, reviewing and scoring applications - £millions

UK Research and Innovation@ukri.org · 6mo ago

Today, we're sharing an open letter from our Chief Executive, Professor Sir Ian Chapman, outlining changes to UKRI investment approach, and addressing concerns about research funding and the financial position of STFC. Read his letter here: www.ukri.org/news/open-le...

Happy to share a new preprint from the lab: Marko became interested in whether the disordered linker of FtsZ might influence how the protein organizes into the Z-ring. And this led to some surprising findings! Preprint: www.biorxiv.org/content/10.1...

Charge segregation in the C-terminal linker of FtsZ enables Z-ring scaling with prokaryotic cell width

Bacterial cytokinesis is orchestrated by the Z-ring, a cytoskeletal structure formed by treadmilling filaments of the tubulin-like GTPase FtsZ. During assembly, filament curvature must match the cell ...

biorxiv.org

I’m happy to share the main result of my PhD, which you can find on bioRxiv www.biorxiv.org/content/10.6.... If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10

SAVE THE DATE! The next instalment of the long-running Bacterial and Archaeal Cell Division Conference will take place at www.marriott.com/en-us/hotels..., Italy from the 20th to 23rd of April 2027. Organisers: me, @s-lab.bsky.social, @awehenkel.bsky.social. More info soon. #MicroSky

Our first lab paper is out. Large-scale testing of antimicrobial lethality at single-cell resolution predicts mycobacterial infection outcomes. From single cells to patients, across tuberculosis and M. abscessus. 👉 doi.org/10.1038/s415... 👇 Thread

Fabian was quicker :) But yes, we have an open postdoc position in bacterial bioenergetics and membrane biology, using on B. subtilis as the model. Come join us! @cbcb-newcastle.bsky.social is a great place to work, and we are a friendly, international lab. Visa+IHS fees covered. #microsky

Molecular Microbiology@molmicrounihoh.bsky.social · 7mo ago

PostDoc position in Newcastle upon Tyne: @henrikstrahl.bsky.social