Patrick Laing

@plaing94.bsky.social

Cognitive neuroscientist, Postdoc Fellow at UT Austin. Studying emotional learning & memory, PTSD, TBI, neuroimaging. Australian in Texas

New paper by Bruno Moses, Enzo Tagliazucchi, & me in which we critique the Entropic Brain Hypothesis & neural entropy metrics regarding what they can tell us about psychedelic fx. Lots of technical and theoretical points, but I'd like to highlight a few. 1/10 www.sciencedirect.com/science/arti...

A critical review of brain entropy as a biomarker of the psychedelic state

Serotonergic psychedelics induce profound alterations in consciousness, giving rise to an altered state commonly referred to as the psychedelic state.…

sciencedirect.com

This paper has been a long time coming. Instead of reanalyzing the same old resting-state fMRI datasets, we combined nearly all datasets around the world. Note that we didn't exactly find indisputable evidence for "default mode network disintegration." www.nature.com/articles/s41...

An international mega-analysis of psychedelic drug effects on brain circuit function - Nature Medicine

Analysis of neuroimaging datasets across five major psychedelics revealed a shared brain signature and provides a comprehensive insight into how these drugs reorganize brain architecture.

nature.com

New lab paper: "Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis." Across 17 different studies, fear conditioning consistently distorted temporal source memory for information encoded before and after. www.sciencedirect.com/science/arti...

Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis

Episodic memory allows us to remember when an event occurred by situating it within a coherent temporal context. Pavlovian fear conditioning, a widely…

sciencedirect.com

Excited to share a new paper w Dani Bassett on "Causation in neuroscience: keeping mechanism meaningful" in Nature Reviews Neuroscience We explore different meanings of mechanism in the field, the challenges this presents & how to move forward. 🧠 www.nature.com/articles/s41...

Causation in neuroscience: keeping mechanism meaningful - Nature Reviews Neuroscience

‘Mechanism’ is a frequently used causal concept in neuroscience but can have different meanings that are often not specified. In this Review, Ross and Bassett explore these different meanings and ...

nature.com