Awesome story on emergence of novelty! Years of work and endless perseverance, congratulations Alejandro and @jamesjulianross.bsky.social 💪 I'm also happy and proud to be a part of this project :)

Alejandro Burga@arburga.bsky.social · 3mo ago

🧬 New research from the Burga lab! We took a closer look at a rogue selfish protein and caught evolution in the act of turning something old into something radically new 💡 (a.k.a. neofunctionalization) @imbavienna.bsky.social www.biorxiv.org/content/10.6... Curious? Here’s a breakdown:

Reminder: PhD position in my lab is open for two more weeks. How do germ cells use their own private transcription factors? Come help us find out. Fully funded. Deadline May 1. Flyer attached — please boost! 🙏

Peter Andersen@germline.bsky.social · 4mo ago

Germ cells have their own versions of core transcription factors and fertility depends on them. We're hiring a PhD student to figure out how! 📢 Fly genetics + proteomics + genomics. Fully funded. Aarhus University 🇩🇰 Deadline May 1 👇 Please share with anyone who might be interested!

Nature News on the tantalising possibility of the first documented sex-ratio distorter in humans. www.nature.com/articles/d41...

Is a ‘selfish gene’ making a Utah family have twice as many boys as girls?

Genealogy study claims first conclusive case of sex ‘distortion’ in humans — but not all researchers are convinced.

nature.com

Cow Tools! We have lived alongside cows for nearly 10,000 years. We breed them and exploit them It is now, only now, that we have discovered THEY CAN USE TOOLS Here I describe our study (paper) www.sciencedirect.com/science/arti... in @currentbiology.bsky.social with @auersperga.bsky.social

Last Friday over dinner, we talked with @svenklumpe.bsky.social and @jnoms.bsky.social about this very creative paper—and quickly went off track. Why? Because, as Sven put it, Vaults ( #Vaults ) remain the “siren 🧜‍♀️ of cell biology 🔬” intriguing and attractive, but maddeningly hard to figure out. 1/3

Science Magazine@science.org · 7mo ago

The barrel-shaped structures found by the thousands in most animal cells are one of biology’s biggest mysteries. But although researchers haven’t figured out the function of these “vaults,” they now report a new use for the puzzling particles. Learn more: https://scim.ag/49pv8mB

Thrilled to share that I recently got a position of an Assistant Professor/SciLifeLab Fellow at Stockholm University, where I will continue my work on #lichen symbiosis. The lab opens in April 2026, and if you are interested in joining please get in touch! #newPI

Beautiful story on the evolutionary response to fly telomeres battling the genome they protect the ends of! Also, nice to see that the dream data clarity we all imagine when starting a project can actually materialize! www.science.org/doi/10.1126/... @sungyalin.bsky.social @levine-lab.bsky.social

Rapid compensatory evolution within a multiprotein complex preserves telomere integrity

Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...

science.org

Happy to share that my PhD project is finally published!🪱✨ Selfish genes are found across the tree of life. They can disrupt inheritance patterns and at the same time act as units for molecular innovation. Here we tried to answer one big question: how do selfish genes emerge in the first place?

Nature Ecology & Evolution@natecoevo.nature.com · 8mo ago

Recurrent evolution of selfishness from an essential tRNA synthetase in Caenorhabditis tropicalis 🧪 www.nature.com/articles/s41...

A new preprint from the lab. I won't do a tweetorial until this is peer reviewed, but I think it's a banger, led by @JedNzy. It's about Rubisco and what chaperones are really for. He's on the market, get him while you can. www.biorxiv.org/content/10.1...

Origin of chaperone dependence and assembly complexity in Rubisco biogenesis

Molecular chaperones assist with the folding and assembly of protein clients. Consequently, they are essential to diverse cellular functions. In most aerobic photosynthetic organisms such as B-cyanoba...

biorxiv.org

1/ How do animals develop immunity against a newly encountered transposable element from scratch? Our study reveals that the mobility of TEs is their Achilles heel, allowing hosts to develop a powerful small RNA-mediated silencing response. www.biorxiv.org/content/10.1...

Antisense transposon insertions into host genes trigger piRNA mediated immunity

Transposable elements pose a persistent threat to genome integrity, yet how host defense systems adapt to newly invading elements remains poorly understood. Here, we reveal how Drosophila melanogaster...

biorxiv.org

bioRxiv Genetics@biorxiv-genetic.bsky.social · last yr.

Antisense transposon insertions into host genes trigger piRNA mediated immunity https://www.biorxiv.org/content/10.1101/2025.07.28.667215v1

I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/ www.biorxiv.org/content/10.1...

Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium

Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...

biorxiv.org

Congratulations to Polina Tikanova on the completion of her PhD! Polina, a researcher in the Burga Lab, presented her work on “Molecular mechanisms of intra- and interspecific genomic conflict” at her PhD defense.