Prof Derek Connolly
@profderekconnolly.bsky.social
Cardiologist in Birmingham UK
Great "PCCS unscripted" podcast on CKD and cardiovascular disease with the wonderful Professor Kieran McCafferty and our own Dr Xenophon Kassianides well worth the listen 📻 open.spotify.com/episode/2Gy9... @pccs.bsky.social
Rethinking Kidney Care in Everyday Practice
Spotify video
open.spotify.com
🇬🇧Our UK substudy of the SANTORINI lipid lowering study shows that UK LDL levels remains suboptimal and don't reach NICE targets [which are already much more lax than @escardio targets] work to do ! bmjopen.bmj.com/content/16/4...
bmjopen.bmj.com
Fantastic to talk with my friend Prof Divaka Perera on the @MayoClinic / British Cardiovascular Society course with the amazing Rajiv Gulati, Malcolm Bell and Louise Buchanan The audience questions were excellent 👌🏻
We have a another way to lower LDL in Heterozygous FH The CETP inhibitor Obicetrapib lowers LDL −36.3%, apolipoprotein B −24.4%, non-HDL cholesterol −34.5% and lipoprotein(a) −45.9%, as well as increasing HDL +138.7% and no major adverse events nature.com/articles/s41...
Obicetrapib in patients with heterozygous familial hypercholesterolemia: the BROOKLYN randomized clinical trial - Nature Medicine
In a randomized trial enrolling 354 patients with heterozygous familial hypercholesterolemia on maximally tolerated lipid-lowering therapy, treatment with the cholesteryl ester transfer protein inhibi...
nature.com
The Midland Metropolitan University Hospital team have organised this excellent course on Coronary CT in guiding PCI Helped by @GeneralElectric Here is the link landing1.gehealthcare.com/AQLA-UKI-IMG... @BCIS_uk @BritishCardioSo @vinoda_sharma
CT Guided PCI Course - Registration Page
f47dac7e-5995-46e1-8ccd-ad3d1f2c3191
landing1.gehealthcare.com
NICE have caught up with science ! GIve metformin, SGLT2i and GLP-1s in CAD and DM www.nice.org.uk/guidance/ng2...
Initial medicines | Type 2 diabetes in adults: management | Guidance | NICE
nice.org.uk
Looking forward to helping with this webinar with a phenomenal faculty; use the QR code to register 💛Lipid-lowering therapy: how to improve adherence and achievement of treatment goals💛 Thursday 5 February 2026 from 18:00 CET 19:00 GMT
This is a truly excellent podcast My friend Prof Kosh Ray in the best of form Have a listen ! open.spotify.com/episode/6ieK...
Lipid Management MythBusters
PCCS Podcast · Episode
open.spotify.com
Truly amazing to be talking at the 4th World of Lipidology in the wonderful city of Vienna with some of my heroes and many of my friends
Preventive Cardiology is now centre stage Cardiometabolic medicine needs to be an independent Training theme for cardiologists in training Cardiologists should now be diabetologists, nephrologists, hypertension & obesity specialists and vice versa academic.oup.com/eurheartj/ad...
CardioMetabolic medicine: the advent of systems cardiology and the new cardiovascular generalist?
Abstract. Cardiometabolic medicine is centre stage currently as it integrates organ dysfunction in the pancreas, kidney, liver, and the heart induced by th
academic.oup.com
Preventing cardiovascular disease makes both moral and economic sense www.medscape.com/viewarticle/... @pccs.bsky.social
Experts Suggest NHS Heart Risk Checks From Age 25
Starting NHS heart health assessments at 25, not 40, could help tackle soaring lifetime cardiovascular risk and reduce preventable early deaths.
medscape.com
Well done team Our paper on “Advancing Cardiovascular, Kidney, and Metabolic Medicine: A Narrative Review of Insights and Innovations for the Future” is on line link.springer.com/article/10.1...
Advancing Cardiovascular, Kidney, and Metabolic Medicine: A Narrative Review of Insights and Innovations for the Future - Diabetes Therapy
Cardiovascular, kidney and metabolic (CKM) conditions are interrelated, significantly contributing to morbidity, mortality and healthcare burden. Despite therapeutic advances, traditional disease-spec...
link.springer.com
"The present meta-analysis suggests that individuals with AF symptoms have no difference in the hazard of all-cause mortality, CV mortality, thromboembolism, stroke, hospitalization, & MI compared to asymptomatic patients" very important! @pccs.bsky.social academic.oup.com/eurheartj/ar...
Major clinical outcomes in symptomatic vs. asymptomatic atrial fibrillation: a meta-analysis
AbstractBackground and Aims. Current guidelines suggest that asymptomatic atrial fibrillation (AF) is independently associated with increased risks of stro
academic.oup.com
Fascinating viewpoint on men’s health in the UK @bbchealth @PCCS_UK www.bbc.co.uk/news/article...
Why men are so unhealthy - and what can be done
Men are more likely to die prematurely than women - and worse at seeking care when they need it.
bbc.co.uk
Be aggressive with SBP in DM💥 In patients with type 2 diabetes & an🔼risk of CVD, the incidence of major cardiovascular events was lower with intensive treatment targeting a systolic blood pressure of <120 mmHg than with standard treatment of< 140 mmHg www.nejm.org/doi/full/10....
Intensive Blood-Pressure Control in Patients with Type 2 Diabetes | NEJM
Effective targets for systolic blood-pressure control in patients with type 2 diabetes are unclear. We enrolled patients 50 years of age or older with type 2 diabetes, elevated systolic blood press...
nejm.org
🌍 Our real-world paper shows GLP1s are associated with lower risk of MACE & less costs than DPP4s or insulin in T2DM at higher CV risk 💔 link.springer.com/article/10.1... @pccs.bsky.social @goggledocs.bsky.social @sabouretcardio.bsky.social @astonuniversity.bsky.social @swbhnhs.bsky.social
Real-World Comparisons Between Glucagon-Like Peptide-1 Receptor Agonists and Other Glucose-Lowering Agents in Type 2 Diabetes: Retrospective Analyses of Cardiovascular and Economic Outcomes in England...
Introduction Clinical trials have demonstrated that glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce the risk of major adverse cardiovascular events (MACE) in adults with type 2 diabetes (T...
link.springer.com
On my way back from a fantastic lecture tour in Arabia What a wonderful place with such friendly people 🇸🇦🌅
Coronary CT angiography-guided management of patients with stable chest pain helps triage patients The 10 year outcomes from the SCOT-HEART randomised controlled trial in Scotland show on going large benefits CTCA remains the diagnostic testing choice 🔗 hubs.li/Q033TWjt0
Coronary CT angiography-guided management of patients with stable chest pain: 10-year outcomes from the SCOT-HEART randomised controlled trial in Scotland
After 10 years, CCTA-guided management of patients with stable chest pain was associated with a sustained reduction in coronary heart disease death or non-fatal myocardial infarction. Identification o...
hubs.li
I often see GLP1s stopped in HF but in this study in patients with obesity-related HFpEF T2DM,Semaglutide improved HF & reduced BMI independent of baseline HbA1c with lower rates of hypoglycaemia than placebo. www.thelancet.com/journals/lan...
Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic o...
Semaglutide 2·4 mg improved heart failure-related symptoms and physical limitations, and reduced bodyweight in patients with obesity-related HFpEF and type 2 diabetes, all independently of baseline Hb...
thelancet.com
I am impressed at how Fergus Walsh has covered the science and benefits of #GLP1 on BBC Panorama tonight in the UK a very balanced, scientifically correct, review of weight loss therapies in the UK including the inequity Well done www.bbc.co.uk/iplayer/epis...
Panorama - Weight Loss Jabs and the NHS
The new generation of weight loss drugs is now available on the NHS and Panorama has exclusive access to one of the UK’s top hospitals as it rolls out Wegovy, also known as Ozempic.
bbc.co.uk
Just on the plane coming back to the UK from a mini lecture tour of India. My first time in this fantastically enthusiastic and friendly country 🇮🇳 Thank you for the kind invitation and amazing hospitality 🙏🏻 I will be back 🤞🏻
Chlorthalidone vs Hydrochlorothiazide & Kidney Outcomes in Patients With #Hypertension Secondary Analysis of a RCT #CardioSky #NephroSky #MedSky jamanetwork.com/journals/jam... @jama.com @vietheartpa.bsky.social @load-dependent.bsky.social @psatishmd.bsky.social
Have you seen the agenda for the PCCS 5th Spring Conference: Evidence into Practice? Check it out on our website now and register for free: pccsuk.org/events/64/pc...
There is clear evidence that commencing patients on combination therapies to lower LDL cholesterol makes enormous sense Read these articles and see why ! www.ecrjournal.com/articles/com... doi.org/10.1093/eurh... doi.org/10.1093/eurh...
Commencement of Atorvastatin and Ezetimibe Immediately in Patients Presenting with Acute Coronary Syndrome
Lipids are implicated in the development of coronary atherosclerosis. Achieving a significant reduction in lipid levels remains a crucial aspect of secondary prevention following an acute
ecrjournal.com
t's the time of the year for New Year Resolutions 🔔🗓️ If you smoke, just how how many years, and what percentage of your remaining life, will you lose if you keep smoking 🚬 this paper tells you www.ajpmonline.org/article/S074...
The Benefits of Quitting Smoking at Different Ages
Quantifying the impact of smoking on life expectancy and the potential benefits of smoking cessation is crucial for motivating people who smoke to quit. While previous studies have attempted to estimate these effects, they were conducted more than a decade ago and did not include a significant demographic, people over 65 years old who smoke.
ajpmonline.org
Automated Breast Arterial Calcium Score Is Associated With CV Outcomes & Mortality #CardioSky #RadSky #JACCAdvances www.jacc.org/doi/10.1016/... @csilvers.bsky.social @katehanneman.bsky.social @erinmichos.bsky.social @vietheartpa.bsky.social @drmarthagulati.bsky.social @jaccjournals.bsky.social
