After six months of repeated shear stress, prostate cancer cells were induced to survive circulation-like force. CALB2 rose in those cells, but it does not appear to explain all of the resistance. doi.org/hccg9f
New mechanoresistant cancer cells show how they survive high stress environments
When a cancer cell leaves the original tumor to spread to a new, faraway location, it first has to survive what most cells cannot: periodic high-force moments in the vessels and heart of up to 5,000 dynes per centimeter squared as it circulates throughout the body.
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